Slow Brain Oscillations of Sleep, Resting State and Vigilance

Preface

Acknowledgments

Slow brain oscillations of sleep, resting state, and vigilance

Introduction

Slow oscillations of sleep: When, where, who, and why?

Even slower: The when, where, who, and why of ISOs

Conclusion

Electrophysiological correlates of sleep homeostasis in freely behaving rats

Behavior and brain activity in waking and sleep

Global and local regulation of sleep

Homeostatic sleep pressure is reflected in the amplitude and slopes of sleep slow waves

Homeostatic sleep pressure is reflected in slopes of the early and late components of electrically evoked cortical responses

Increased homeostatic sleep pressure affects cortical plasticity

Homeostatic sleep pressure is reflected in synchronization of cortical neurons

Concluding remarks

Acknowledgments

Involvement of cytokines in slow wave sleep

Introduction

IL1β and TNFα in sleep regulation

Upstream and downstream events in the cytokine sleep regulatory cascade

Brain organization of sleep

Sleep function

Acknowledgments

Genetic determination of sleep EEG profiles in healthy humans

Introduction

Sleep–wake regulation

Heritability of waking EEG

Trait-like nature of sleep and sleep EEG characteristics

Heritability of sleep EEG

Genetic polymorphisms affecting sleep and sleep EEG

Concluding remarks

Acknowledgments

Developmental aspects of sleep slow waves

Abbreviations

Introduction

Characteristics of slow waves

Development of slow waves—disparities in infants, children and adolescents

Developmental aspects and their relation to the function of slow waves

Slow waves and their relation to behavior

Discussion of the inverted U-shape time course of SWA

Conclusion and future perspectives

Acknowledgment

Phasic modulation of cortical high-frequency oscillations by pedunculopontine neurons

Abbreviations

Introduction

The firing of PPN neurons during sleep

Subcortical modulation of slow oscillations: A specific role of the PPN or a widespread mechanism in the reticular-activating system?

Is timing important in neuromodulatory systems?

The gating hypothesis

Acknowledgment

Slow oscillations orchestrating fast oscillations and memory consolidation

Introduction

A model of active system consolidation taking place during slow-wave sleep

Inducing slow oscillations by electrical stimulation

Slow oscillations grouping spindles

Fast spindles versus slow spindles

Slow oscillations grouping hippocampal ripples and memory reactivations

Spindle–ripple events

Conclusion

Acknowledgments

Spontaneous neural activity during human non-rapid eye movement sleep

Introduction

Slow waves

Spindles

Conclusions

Acknowledgments

Neuronal plasticity and thalamocortical sleep and waking oscillations

Abbreviations

Introduction

Sleep and waking oscillations

Neuronal plasticity

Yin and Yang of brain oscillations and plasticity

Acknowledgments

Infraslow (<0.1Hz) oscillations in thalamic relay nuclei

Introduction

Properties and mechanisms of an ISO that is present in acute slices of thalamic relay nuclei maintained in vitro

Concluding remarks

Acknowledgments

Hippocampal–cortical interactions and the dynamics of memory trace reactivation

Cortical modular organization and memory indexing

Sparse versus distributed coding to maximize storage capacity

Basic data structure and analysis of ensemble recordings

Using place cells to study memory

Coherent reactivation of memory traces in hippocampus and neocortex

Memory trace reactivation dynamics during slow-wave sleep

Acknowledgments

Long-range correlation of the membrane potential in neocortical neurons during slow oscillation

Abbreviations

Introduction

Methods: simultaneous intracellular recording from neocortical neurons

Detection of active and silent states

Correlated occurrence of active and silent states in neocortical neurons during slow oscillation

Long-range correlation of membrane potential changes during slow oscillation

Dynamics of the membrane potential correlation: high correlation during the transitions between active and silent states but low correlation within states

Long-range membrane potential correlation: slow rhythm is correlated, but fast fluctuations are not

Summary and conclusions: what is synchronous in neurons during the synchronized EEG?

Acknowledgments

Temporal dynamics of cortical sources underlying spontaneous and peripherally evoked slow waves

Introduction

Where are slow waves?

Are slow waves synchronous?

Are K-complexes nonspecific responses to peripheral stimulation?

Conclusion

Acknowledgments

Sleep and developmental plasticity

Abbreviations

Historical approaches to neonatal sleep function

Sleep and subcortical development in central visual pathways

Sleep and ocular dominance plasticity

Summary

Evoked electrical and cerebral vascular responses during sleep and following sleep deprivation

Abbreviations

Introduction

Methods

Results

Discussion

Conclusion

Acknowledgments

Reduction of nocturnal slow-wave activity affects daytime vigilance lapses and memory encoding but not reaction time or implicit learning

Introduction

Methods

Results

Discussion

Acknowledgments

Spectral characteristics of resting state networks

Introduction

FMRI RSNs across the frequency spectrum

RSN spectra after correcting for the effects of HRF blurring

RSN spectra from perfusion FMRI

Discussion

Acknowledgments

Modulation of the brain’s functional network architecture in the transition from wake to sleep

Introduction

Methods

Results

Discussion

Acknowledgments

Spontaneous fMRI activity during resting wakefulness and sleep

Abbreviations

Introduction

What is spontaneous fMRI activity?

Nonneuronal contributions to the BOLD fMRI signal

Neuronal correlates of the BOLD fMRI signal

Spontaneous fMRI activity during sleep

Origin and role of spontaneous fMRI activity

Use of spontaneous fMRI to study brain connectivity

Hypnotic modulation of resting state fMRI default mode and extrinsic network connectivity

Introduction

Methods

Results

Discussion

Acknowledgments

Multimodal neuroimaging in patients with disorders of consciousness showing “functional hemispherectomy”

Abbreviations

Introduction

Data acquisition and analysis

Results

Multimodal imaging

Discussion

Acknowledgments

Roles of multiscale brain activity fluctuations in shaping the variability and dynamics of psychophysical performance

Abbreviations

Introduction

Infraslow spontaneous brain activity fluctuations in fMRI

Correlation of BOLD-signal fluctuations with behavioral dynamics

Electrophysiological characterization of infraslow fluctuations

Zooming-in on neuronal oscillations

Direct effects of oscillation phase on behavioral dynamics

Amplitude dynamics link neuronal oscillations and ISFs

Cross-scale binding by CF phase-amplitude and phase–phase interactions

Dissection of causal from correlated

Conclusion

Acknowledgments