Sleep and The Maturing Nervous System

List of ParticipantsPrefaceThe Maturation of Neural Elements 1 Principles of Synaptogenesis and Their Application to Ontogenetic Studies of Mammalian Cerebral Cortex Comparative Neuronal Morphogenesis and Synaptogenesis in Immature Cerebral Cortex: Functional Implications Excitability Properties of Dendrites of Immature Cortical Neurons Correlation Synaptogenesis and Evoked Potentials of Immature Cerebral Cortex Comments References 2 The Development of Synapses in the Rat Cerebellar Cortex Text References Invited Discussion (Chapter 1 and 2) by Guenter H. Rose References General Discussion (Chapter 1 and 2) References 3 Maturing Neuronal Subsystems: The Dendrites of Spinal Motorneurons Techniques Results Discussion Conclusion References Invited Discussion by Paul D. Coleman References General Discussion ReferencesNeurochemical Factors in the Maturation of Sleep Behavior 4 Coordination between Excitation and Inhibition: Development of the GABA System Introduction Cerebellum The GABA System in the Cerebellum of the Developing Chick GABA in Other Vertebrate Neuronal Systems Comment References General Discussion 5 Contributions of Differential Housing to Brain Development: Some Implications for Sleep Behavior Text References General Discussion 6 The Role of Biogenic Amines in Sleep Text References General Discussion References 7 Developmental Changes in Neurochemistry during the Maturation of Sleep Behavior Text References General Discussion References 8 Maturation of Neurobiochemical Systems Related to the Ontogeny of Sleep Behavior Text ReferencesDevelopment of EEG and Activity Patterns in Relation to Sleep 9 Development of Wakefulness-Sleep Cycles and Associated EEG Patterns in Mammals Interspecies Similarities Interspecies Differences References 10 The Basic Rest-Activity Cycle and Sleep: Developmental Considerations in Man and Cats Text Discussion References 11 Development of States in Infants Components of State Development of State Variables Development of Sleep States Sleep and Waking States Animal Studies Conclusions References Invited Discussion: by Nathaniel Kleitman Reference Invited Discussion by David R. Metcalf References General Discussion ReferencesDevelopment of Reflex Patterns in Sleep 12 The Somatosensory Cerebral Evoked Potentials of the Sleeping Human Newborn Immaturity of the Human Brain at Birth Evoked Potentials in REMS and SWS Comparison with Vertex Responses Amplitude of Evoked Potentials in Sleep States The Effect of Intervals Between Stimuli Conclusions and Summary References Invited Discussion by Mortimer G. Rosen References General Discussion 13 Patterns of Reflex Excitability during the Ontogenesis of Sleep and Wakefulness Introduction Brain Stem Reflex Activity in the Kitten Discussion References Invited Discussion by Dennis J. McGinty References Development of Early Motor Activity in the Monkey Selected Bibliography General Discussion References 14 Patterns of Reflex Behavior Related to Sleep in the Human Infant The Definition of State Statement of the Problem Proprioceptive and Vestibular Reflexes Exteroceptive Skin Reflexes Acoustic Orienting Response Discussion References Invited Discussion by F. J. Schulte References Invited Discussion by Elliot D. Weitzman Reference General Discussion ReferenceDevelopmental Aspects of Normal and Abnormal Sleep Behavior 15 Sleep Deprivation and the Organization of the Behavioral States Independent Processes in the States of Vigilance The Dynamism of Sleep States and Total Sleep Deprivation Selective Deprivation on Rapid Eye Movement Sleep Dissociative Aspects of Sleep and Wakefulness: Implications for Selective and Total Sleep Deprivation Conclusions References Invited Discussion by Howard P. Roffwarg Reference General Discussion References 16 Development of Sleep Patterns in Autistic Children Clinical Considerations Neurophysiological Considerations Developmental Considerations Sleep Studies in Normal Subjects Sleep Studies in Autistic Children Central Vestibular Mechanisms Conclusion Summary References 17 Sleep in Mental Retardation Quantitative Variations of the Sleep Stages Relationship of Etiology to Sleep Variables in the Mentally Retarded Qualitative Variations Genetic Aspects of Sleep The Eye Movements of Sleep Summary References 18 Maternal Toxemia, Fetal Malnutrition, and Bioelectric Brain Activity of the Newborn Subjects Methods Results Discussion Summary References General Discussion References 19 Summary and Concluding Remarks Historical Background Some Attempted Definitions Some Comments on Works in This Volume Some General Comments ReferencesSubject Index