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SERS for Point-of-care and Clinical Applications
- 1st Edition - August 12, 2022
- Editor: Andrew Fales
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 0 5 4 8 - 8
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 0 9 1 0 - 3
SERS for Point-of-care and Clinical Applications focuses on the use of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in clinical… Read more
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Request a sales quoteSERS for Point-of-care and Clinical Applications focuses on the use of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in clinical and point-of-care settings. Sections provide an overview of SERS biomedical applications, providing in-depth information about point-of-care and clinical applications of SERS using specific examples from current literature. These applications are not always immediately evident to newcomers in the field, as Raman and SERS are often introduced as analytical methods for chemical analysis. This book offers a concise introduction to the biomedical applications of SERS for graduate students, scientists and researchers in all related fields.
- Highlights point-of-care applications for SERS
- Covers the recent biomedical applications of SERS carried out by leaders in the field
- Includes chapters on SERS probes and labels and label-free uses of SERS
Scientists, researchers, and graduate students using Surface-Enhanced Raman Spectroscopy (SERS) in the fields of chemistry, biology, biophotonics, nanotechnology, and physics who are interested applying SERS in clinical and point-of-care settings
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Editor biography
- Chapter 1. Data analysis in SERS diagnostics
- Introduction
- General data processing workflow
- Data preprocessing
- Models
- Verification of results
- Hyperparameter optimization
- Concluding remarks
- Chapter 2. Label-free SERS techniques in biomedical applications
- Introduction
- Oncological diseases
- Neurological diseases
- Infectious diseases
- Future challenges and perspectives
- Chapter 3. SERS probes and tags for biomedical applications
- Introduction
- Design considerations
- Chapter 4. SERS biosensors for point-of-care infectious disease diagnostics
- Introduction
- Antibody-based SERS biosensors
- Aptamer-based SERS biosensors
- Nucleic acid–based SERS biosensors
- SERS biosensors without bioreceptor
- Conclusion
- Chapter 5. SERS-based molecular sentinel nanoprobes for nucleic acid biomarker detection
- Introduction
- Development of the iMS nanoprobe for label-free homogenous biosensing
- Detection of miRNA biomarkers within biological samples
- Multiplexed detection of miRNA biomarkers
- Conclusion
- Chapter 6. SERS detection of oral and gastrointestinal cancers
- Introduction
- Oral cancer
- Esophageal cancer
- Stomach cancer
- Intestinal cancer
- Concluding remarks
- Chapter 7. In vivo imaging with SERS nanoprobes
- Introduction
- Raman imaging with SERS nanoprobes
- In vivo imaging with SERS nanoparticles—multiplexing potential
- Biological barriers and opportunities
- Passive tumor targeting
- Opsonization/sequestration by the mononuclear phagocyte system
- Sequestration based on physicochemical properties
- Blood–brain barrier
- Molecular targeting
- Ex vivo SERS-based molecular imaging
- In vivo molecular imaging with SERS nanoprobes
- Multimodal imaging using SERS nanoprobes
- The future of in vivo Raman imaging
- Imaging deeper
- SERS and endoscopy
- Spatially offset optics
- Imaging faster
- Nanoprobe administration
- Conclusion
- Index
- No. of pages: 256
- Language: English
- Edition: 1
- Published: August 12, 2022
- Imprint: Elsevier
- Paperback ISBN: 9780128205488
- eBook ISBN: 9780128209103
AF
Andrew Fales
Andrew Fales is a Staff Fellow in Biomedical Engineer and works in the Division of Biomedical Physics, Office of Science and Engineering Laboratories at the Center for Devices and Radiological Health, U.S. Food and Drug Administration.
Affiliations and expertise
Staff Fellow, Biomedical Engineer, Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug AdministrationRead SERS for Point-of-care and Clinical Applications on ScienceDirect