
Samaranayake’s Essential Microbiology for Dentistry
- 6th Edition - January 29, 2024
- Imprint: Elsevier
- Author: Lakshman Samaranayake
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 2 1 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 8 2 1 - 0
A sound knowledge of microbiology is essential for all dental professionals – it’s the key to understanding major oral pathologies, from tooth decay to gum disease, as well as the… Read more

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Request a sales quoteA sound knowledge of microbiology is essential for all dental professionals – it’s the key to understanding major oral pathologies, from tooth decay to gum disease, as well as the regimentation of infection control in a successful dental practice. Samaranayake’s Essential Microbiology for Dentistry once again, provides a comprehensive coverage of the basics of clinical oral microbiology and immunology and their relevance to oral disease, as well as the cotemporary discoveries of the oral microbiome, and the constituent flora. Both the novice student, as well as the experienced professionals are guided, in a stepwise manner, through a tour of the microbial world and how they impact oral health. The reasoned, bare bones approach to the essential elements of the subject is, as in previous editions fresh, lucid and logical. The sixth edition of this popular book, now translated into four different languages, has been fully revised and reformatted and includes brand new sections on emerging topics such as COVID-19 and infection control.
- Latest evidence throughout, updated to incorporate discoveries appertaining to the oral microbiome, and the international guidelines on infection control.
- Ample artwork and clinical pictures to explain complex structures, intricate pathological processes, and disease management principles.
- Friendly accessible writing style that helps students better understand and retain key information.
- Self-assessment tasks to monitor progress and prepare for graduate and postgraduate examinations
- Easy to follow - highlighted important information, and helpful summaries of key facts.
- A comprehensive glossary and a list of abbreviations
- An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud
- Cover image
- Title page
- Copyright
- Contents
- Preface
- Online Study for Students
- Part 1 General microbiology
- 1 Why Study Microbiology?
- A Note on Emerging and Re-emerging Infections
- About This Book
- Further Reading
- 2 Bacterial Structure and Taxonomy
- Eukaryotes and Prokaryotes
- Morphology
- Taxonomy
- Review Questions (Answers on p. 388)
- Further Reading
- 3 Bacterial Physiology and Genetics
- Bacterial Physiology
- Bacterial Genetics
- Recombinant DNA Technology in Microbiology
- The Era of ‘-omics’
- Review Questions (answers on p. 388)
- Further Reading
- 4 Viruses and Prions
- Structure
- Taxonomy
- Viral Replication
- Pathogenesis of Viral Infections
- Cellular Antiviral Response
- Prions and Prion Diseases
- Review Questions (answers on p. 388)
- Further Reading
- 5 Pathogenesis of Microbial Disease
- General Aspects of Infection
- Pathogenesis of Bacterial Disease
- Pathogenesis of Viral Disease
- Pathogenesis of Fungal Disease
- Koch’s Postulates
- Review Questions (Answers on p. 388)
- Further Reading
- 6 Diagnostic Microbiology and Laboratory Methods
- Diagnostic Microbiology
- Laboratory Methods
- Bacterial Identification
- Immunological Methods
- Laboratory Investigations Related to Antimicrobial Therapy
- Appropriate Specimens in Medical Microbiology
- Laboratory Isolation and Identification of Viruses
- Diagnosis of Fungal Infections
- Review Questions (Answers on p. 388)
- Further Reading
- 7 Antimicrobial Chemotherapy
- Bacteriostatic and Bactericidal Antimicrobial Agents
- Principles of Antimicrobial Therapy
- Pharmacodynamics of Antimicrobials
- Failure of Antimicrobial Therapy
- Antimicrobials Commonly Used in Dentistry
- Antibacterial Agents
- Antifungal Agents
- Antiviral Agents
- Review Questions (Answers on p. 388)
- Further Reading
- Part 2 Basic immunology
- 8 The Immune System and the Oral Cavity
- The Immune System: General Considerations
- The Innate Immune System
- The Adaptive Immune System
- Cells of the Immune System
- Oral Defence Mechanisms
- Innate Immune Mechanisms
- The Oral Mucosal Epithelium
- Adaptive Immunity in Oral Health and Disease
- Review Questions (Answers on p. 388)
- Further Reading
- 9 The Immune Response
- Antibodies
- Cytokines
- B Cell Activation
- Antigen Processing and Presentation
- T-Helper Subsets
- Target Cell Killing
- Activation of Macrophages
- Regulation of the Immune Response
- Immunological Memory
- Review Questions (Answers on p. 389)
- Further Reading
- 10 Immunity and Infection
- Immunity to Bacteria
- Immunity to Viruses
- Immunity to Parasites
- Immunity to Fungi
- Vaccination
- ‘-omics’ Developments Impacting Oral Immunology
- Review Questions (Answers on p. 389)
- Further Reading
- Part 3 Microbes of relevance to dentistry
- 11 Streptococci, Staphylococciand Enterococci
- Streptococci
- Staphylococci
- Enterococci
- Micrococci
- Review Questions (Answers on p. 389)
- Further Reading
- 12 Lactobacilli, Corynebacteria and Propionibacteria
- Lactobacilli
- Corynebacteria
- Propionibacteria
- Review Questions (Answers on p. 389)
- Further Reading
- 13 Actinomycetes, Clostridia and Bacillus Species
- Actinomycetes
- Nocardia
- Clostridia
- Bacillus
- Review Questions (Answers on p. 389)
- Further Reading
- 14 Neisseriaceae, Veillonella, Parvobacteria and Capnocytophaga
- Neisseriaceae
- Veillonella
- Parvobacteria
- Haemophilus Species
- Bordetella
- Review Questions (Answers on p. 389)
- Further Reading
- 15 Enterobacteria
- General Characteristics of Enterobacteria
- Eschericheae
- Salmonellae
- Shigellae
- Klebsielleae
- Pseudomonads
- Review Questions (Answers on p. 389)
- Further Reading
- 16 Vibrios, Campylobacters and Wolinella
- Vibrios
- Campylobacters
- Wolinella
- Review Questions (Answers on p. 390)
- Further Reading
- 17 Bacteroides, Tannerella, Porphyromonas and Prevotella
- Bacteroides
- Tannerella
- Porphyromonas
- Prevotella
- Review Questions (Answers on p. 390)
- Further Reading
- 18 Fusobacteria, Leptotrichia and Spirochaetes
- Fusobacteria
- Leptotrichia
- Spirochaetes
- Treponema
- Borrelia
- Leptospira
- Review Questions (Answers on p. 390)
- Further Reading
- 19 Mycobacteria and Legionellae
- Mycobacteria
- Legionella
- Further Reading
- Review Questions (Answers on p. 390)
- 20 Chlamydiae, Rickettsiae and Mycoplasmas
- Chlamydiae
- Rickettsiae
- Mycoplasmas
- Further Reading
- Review Questions (Answers on p. 390)
- 21 Viruses of Relevance to Dentistry
- DNA Viruses
- RNA Viruses
- Viruses and Cancer
- Further Reading
- Review Questions (Answers on p. 390)
- 22 Fungi of Relevance to Dentistry
- Morphology
- Reproduction
- Classification
- Cultural Requirements
- Pathogenicity
- Human Mycoses
- Yeasts
- Filamentous and Dimorphic Fungi and Oral Disease
- Review Questions (Answers on p. 390)
- Further Reading
- Part 4 Systemic Infections of relevance to dentistry
- 23 Infections of the Respiratory Tract
- Normal Flora
- Important Pathogens of the Respiratory Tract
- Infections of the Upper Respiratory Tract
- Infections of the Paranasal Sinuses and the Middle Ear
- Infections of the Trachea and Bronchi
- Lung Infections
- Severe Acute Respiratory Syndrome (SARS) and Coronavirus Disease 2019 (COVID-19)
- Fungal Infections of the Lower Respiratory Tract
- Respiratory Infections and Dentistry
- Review Questions (Answers on p. 390)
- Further Reading
- 24 Infections of the Cardiovascular System
- Bacteraemia, Septicaemia and Sepsis Syndrome
- Infections of the Heart
- British and US Guidelines on Prophylaxis Against Infective Endocarditis in Patients Undergoing Interventional Procedures
- Dental Procedures That Need Antibiotic Prophylaxis
- Review Questions (Answers on p. 390)
- Further Reading
- 25 Infections of the Central Nervous and Locomotor Systems
- Infections of the Central Nervous System
- Infections of the Locomotor System
- Arthroplasties and Antibiotic Prophylaxis for Dental Procedures
- Review Questions (Answers on p. 391)
- Further Reading
- 26 Infections of the Gastrointestinal Tract
- Normal Flora
- Common Diarrhoeal Diseases
- Less Common and Uncommon Diarrhoeal Diseases
- Nonbacterial Causes of Diarrhoea
- Review Questions (Answers on p. 391)
- Further Reading
- 27 Infections of the Genitourinary Tract
- Normal Flora and the Natural Defences of the Genitourinary Tract
- Sexually Transmitted Infections
- Urinary Tract Infections
- Dentistry and Genitourinary Infections
- Review Questions (Answers on p. 391)
- Further Reading
- 28 Skin and Wound Infections
- Normal Flora
- Skin Infections
- Wound Infections
- Review Questions (Answers on p. 391)
- Further Reading
- 29 Viral Hepatitis
- Signs and Symptoms of Hepatitis
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D (Delta Hepatitis)
- Hepatitis E
- Hepatitis Viruses of Unclear Pathogenicity
- Review Questions (Answers on p. 391)
- Further Reading
- 30 Human Immunodeficiency Virus Infection, AIDS and Infections in Compromised Patients
- Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome
- Human Immunodeficiency Virus
- Acquired Immune Deficiency Syndrome
- Prevention of HIV Infection
- Infections in Compromised Patients
- Xerostomia and Infection
- Review Questions (Answers on p. 391)
- Further Reading
- Part 5 Oral microbiota and oral infections
- 31 Oral Microbiota and the Oralome
- Oral Microbiome and the Oral Microbiota
- Oral Microbiota
- Oral Bacteriome
- Oral Mycobiome
- Oral Virome
- Oral Phageome
- Oral Archaeome
- Oral Protozome
- The Oral Ecosystem
- The Plaque Biofilm
- Review Questions (Answers on p. 391)
- Further Reading
- 32 Microbiology of Dental Caries
- Epidemiology
- Classifications
- Diagnosis
- Aetiology
- Management of Dental Caries
- Review Questions (Answers on p. 392)
- Further Reading
- 33 Microbiology of Periodontal Disease
- The Periodontium
- Classification of Periodontal Disease
- The Progression From Gingivitis to Periodontitis
- Relationship Between Chronic Marginal Gingivitis and Periodontitis
- Acute Necrotizing Ulcerative Gingivitis (ANUG)
- Pericoronitis
- Peri-implant Microbiology
- Clinical Implications of Microbiological Tests in Periodontal Disease
- Review Questions (Answers on p. 392)
- Further Reading
- 34 Dentoalveolar and Endodontic Infections
- Natural History of Dentoalveolar Infections
- Source of Microorganisms
- Apical Dentoalveolar Abscess
- Ludwig’s Angina
- Pericoronitis (See Chapter 33.)
- Periodontal Abscess
- Suppurative Osteomyelitisof the Jaws
- Cervicofacial Actinomycosis
- Facial Lacerations
- Endodontic Infections
- Review Questions (answers on p. 392)
- Further Reading
- 35 Oral Mucosal and Salivary Gland Infections
- Oral Mucosal Infections
- Oral Manifestations of Systemic Mycoses
- Oral Viral Infections
- Oral Manifestations of Bacterial Infections
- Salivary Gland Infections
- Review Questions (Answers on p. 392)
- Further Reading
- Part 6 Cross-infection and control
- 36 General Principles of Infection Control, Standard Precautions and Transmission-Based Precautions
- General Principles of Infection Control
- Routes of Infection
- Standard Infection Control Precautions
- Review Questions (Answers on p. 392)
- Further Reading
- 37 Standard Infection Control Procedures in Dentistry Part I: Personal Protection, Sharps Injuries Protocol and Immunization
- Practice Management and Staff Development
- Infection Control: Specific Practical Features
- Review Questions (Answers on p. 392)
- Further Reading
- 38 Standard Infection Control Procedures in Dentistry Part II: Sterilization, Disinfection and Antisepsis, with a Summary of Transmission-Based Infection Control Procedures
- Sterilization, Disinfection and Antisepsis
- Decontamination
- Decontamination of Instruments
- Sterilization
- Disinfection
- Step 1
- Step 2
- Environmental Disinfection
- Dental Unit Water Lines: Disinfection and Management
- Recommendations on Care of Handpieces and Other Devices Attached to Air and Water Lines
- Dental Radiology
- Laboratory Asepsis
- Office/Surgery Design and Maintenance
- Instrument Recirculation and Office Design
- Disposal of Clinical Waste
- Transmission-Based Precautions
- Contact Precautions: For Ambulatory Clinic Settings
- Droplet Precautions: For Ambulatory Clinic Settings
- Airborne Precautions: For Ambulatory Clinic Settings
- Review Questions (Answers on p. 392)
- Further Reading
- Answers to Review Questions
- Glossary of Terms and Abbreviations
- Index
- Edition: 6
- Published: January 29, 2024
- Imprint: Elsevier
- No. of pages: 424
- Language: English
- Paperback ISBN: 9780443117213
- eBook ISBN: 9780443118210
LS
Lakshman Samaranayake
Affiliations and expertise
Professor of Oral Microbiomics and Infection, School of Dentistry, University of Queensland, Australia; Professor Emeritus, University of Hong Kong; Professor – King James IV, Royal College of Surgeons of Edinburgh (2013).