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Robotics for Cell Manipulation and Characterization
- 1st Edition - April 20, 2023
- Editors: Changsheng Dai, Guanqiao Shan, Yu Sun
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 5 2 1 3 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 2 1 4 - 9
Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advanc… Read more
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Request a sales quoteRobotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers’ comprehension and pinpoint challenges and opportunities for biological and biomedical research.
- Focuses on, and comprehensively covers, robotics for cell manipulation and characterization
- Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization
- Provides insightful outlooks on future challenges and opportunities
Researchers and practitioners who are interested in small-scale robotic systems for cell manipulation and characterization, Healthcare professionals interested in nanoscale, microscale, milli-scale robotic techniques for disease diagnosis and clinical cell surgeries, Undergraduate students who are interested in learning the area of robotics applied to manipulating and characterizing biological cells
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Part I: Robotic cell manipulation
- Chapter 1: Introduction of robotics for cell manipulation and characterization
- Abstract
- 1: Introduction
- 2: Robotic cell manipulation
- 3: Robotic cell characterization
- 4: Summary and outlook
- References
- Chapter 2: Robotic cell injection with force sensing and control
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Microinjection of adherent cells
- 3: Microinjection of suspended cells
- 4: Microforce sensors for cell microinjection
- 5: Current challenges of cell microinjection and future development
- 6: Conclusion
- References
- Chapter 3: Robotic orientation control and enucleation of cells
- Abstract
- 1: Introduction
- 2: Robotic orientation control of cells
- 3: Robotic enucleation of cells
- 4: Conclusion and perspectives
- References
- Chapter 4: Robotic cell manipulation for in vitro fertilization
- Abstract
- 1: Introduction
- 2: Robotic end-effector alignment for sperm immobilization
- 3: Robotic rotation of sperm as deformable linear objects
- 4: Robotic orientation control of deformable oocyte
- 5: Robotic cell penetration with piezo drill
- 6: Summary
- References
- Chapter 5: Robotic cell transport for tissue engineering
- Abstract
- Acknowledgment
- 1: Introduction
- 2: Robotic transport for cell isolating and positioning
- 3: Robotic transport for fabrication and assembly of cellular modules
- 4: Summary
- References
- Chapter 6: Robotic cell biopsy for disease diagnosis
- Abstract
- 1: Introduction
- 2: Generic small cell biopsy system
- 3: Cell biopsy process
- 4: Experiments
- 5: Conclusions
- References
- Chapter 7: 3D force-feedback optical tweezers for experimental biology
- Abstract
- 1: Robotic bio-manipulation
- 2: Optical micromanipulation
- 3: 3D real-time force sensing in optical manipulation
- 4: Evaluation of tracking
- 5: 3D haptic experiments on biologic samples
- References
- Chapter 8: Magnetically driven robots for clinical treatment
- Abstract
- 1: Introduction
- 2: Actuating microrobots using magnetic fields
- 3: Clinical applications for microrobots
- 4: Conclusion
- References
- Part II: Robotic cell characterization
- Chapter 9: Robotic cell electrophysiological characterization for drug discovery
- Abstract
- 1: Introduction
- 2: Discussion
- References
- Chapter 10: Automated cell aspiration for genetic and mechanical analysis
- Abstract
- 1: Introduction
- 2: Automated cell aspiration for mechanical analysis
- 3: Automated cell aspiration for genetic analysis
- 4: Conclusion and outlook
- References
- Chapter 11: Cell characterization by nanonewton force sensing
- Abstract
- 1: Introduction
- 2: Techniques for sensing cell-generated forces
- 3: Internal molecular sensors for detecting cell-generated forces
- 4: Concluding remarks
- References
- Chapter 12: Cellular mechanical measurement by magnetic micro/nanorobots
- Abstract
- 1: Introduction
- 2: Principles of magnetic actuation
- 3: Magnetic systems for magnetic actuation
- 4: Magnetic measurement of cellular and intracellular structure mechanics
- 5: Summary and outlook
- References
- Chapter 13: Nanorobotics for investigating cell mechanics based on atomic force microscopy
- Abstract
- Acknowledgments
- 1: Background
- 2: Atomic force microscopy (AFM)-based nanomanipulator
- 3: Methodology of characterizing cellular mechanics by AFM nanomanipulator
- 4: Applications of AFM nanomanipulator in detecting cell mechanics
- 5: Combining AFM nanorobotics with micropipette for precise drug-induced cellular mechanical analysis
- 6: Summary
- References
- Chapter 14: Robotic manipulation of zebrafish larvae for disease therapy
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Robotic transportation
- 3: Robotic immobilization
- 4: Robotic orientation
- 5: Robotic injection
- 6: Conclusion
- References
- Chapter 15: Acoustic field techniques for cell characterization in health monitoring
- Abstract
- 1: Introduction
- 2: Acoustic techniques
- 3: Cell analysis
- 4: Current challenges and future direction
- References
- Chapter 16: Separation and characterization of cells using electrical field
- Abstract
- Acknowledgments
- 1: Introduction
- 2: Theoretical background
- 3: Cell sorting using the electric field
- 4: Cell characterization
- 5: Conclusion and future perspectives
- References
- Index
- No. of pages: 400
- Language: English
- Edition: 1
- Published: April 20, 2023
- Imprint: Academic Press
- Paperback ISBN: 9780323952132
- eBook ISBN: 9780323952149
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Changsheng Dai
Changsheng Dai is currently a professor at Dalian University of Technology. His research focuses on robotic cell manipulation and medical image analysis. Dr. Dai has published over 20 peer-reviewed papers in premium journals and international conference proceedings such as Nature Reviews Urology, IEEE Transactions on Robotics, and IEEE Transactions on Medical Imaging, and has received the Best Paper Award in Automation at 2019 IEEE International Conference on Robotics and Automation (ICRA), Connaught International Scholarship, William Dunbar Memorial Scholarship in Mechanical Engineering, and Weber and Mariano Scholarship in Biomedical Engineering from the University of Toronto. He served as a peer reviewer for several journals such as IEEE Transactions on Robotics and IEEE Robotics and Automation Letters.
Affiliations and expertise
Professor, Dalian University of Technology, ChinaGS
Guanqiao Shan
Guanqiao Shan is currently a Postdoctoral Fellow at the University of Toronto. His research interests include robotic cell manipulation and characterization, automation at micro-nano scales, intelligent control systems, and medical robotics
Affiliations and expertise
Postdoctoral Fellow, University of Toronto, CanadaYS
Yu Sun
Dr. Sun is a Professor at the University of Toronto. He is a Tier I Canada Research Chair and the Director of Robotic Institute, University of Toronto. His Advanced Micro and Nanosystems Laboratory specializes in developing innovative robotic and AI technologies for reproductive medicine. He was elected Fellow of ASME (American Society of Mechanical Engineers), IEEE (Institute of Electrical and Electronics Engineers), AAAS (American Association for the Advancement of Science), NAI (US National Academy of Inventors), and AIMBE (American Institute of Medicine and Biomedical Engineering) for his work on micro/nano devices, robotic systems and AI technologies.
Affiliations and expertise
Professor, Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada