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RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay

1st Edition, Volume 448 - December 15, 2008

Editors: Lynne E. Maquat, Megerditch Kiledjian

Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 3 7 4 3 7 8 - 7
eBook ISBN:
9 7 8 - 0 - 0 8 - 0 9 2 2 0 7 - 2

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic… Read more

RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay

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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.