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RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways

  • 1st Edition, Volume 449 - December 15, 2008
  • Editors: Lynne E. Maquat, Megerditch Kiledjian
  • Language: English
  • Hardback ISBN:
    9 7 8 - 0 - 1 2 - 3 7 4 5 8 4 - 2
  • eBook ISBN:
    9 7 8 - 0 - 0 8 - 0 9 2 3 3 2 - 1

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic… Read more

RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways

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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.