Ribonucleases
Structures and Functions
- 1st Edition - February 11, 1997
- Latest edition
- Editors: Giuseppe D'Alessio, James F. Riordan
- Language: English
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 4 0 5 9 - 7
Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently… Read more
Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently undergone a resurgence in popularity for the recognition of an extended ribonuclease superfamily with functions ranging from tumour growth and inhibition to self-recognition and neurotoxicity. This volume highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes.
* Never before has discussion of the entire family of ribonucleases and related enzymes been covered in a single volume
* Core chapters focus on the latest structures and functions of pancreatic-type ribonucleases
* Structures and functions of intracellular ribonucleases and nondigestive members of the family are also covered
* How ribonucleases continue to serve as excellent systems with which to uncover the secrets of protein chemistry is demonstrated
* Core chapters focus on the latest structures and functions of pancreatic-type ribonucleases
* Structures and functions of intracellular ribonucleases and nondigestive members of the family are also covered
* How ribonucleases continue to serve as excellent systems with which to uncover the secrets of protein chemistry is demonstrated
Escherichia Coli Ribonucleases: Paradigms for Understanding Cellular RNA Metabolism and Regulation. Barstar and Barnase. Rnase T1/Rnase T2 Family Rnases. Structures and Mechanism of Action of Cytotoxic Ribonuclease I-Sarcin. Plant Ribonucleases. S-Rnases and Other Plant Extracellular Ribonucleases. Evolutionary Reconstructions in the Ribonuclease Family. Evolution of Vertebrate Ribonucleases: Ribonuclease a Superfamily. Pancreatic Ribonucleases. Crystallographic Studies of Ribonuclease Complexes. NMR Solution Structures of Ribonuclease a and Its Complexes with Mono- And Dinucleotides. Seminal Ribonuclease: The Importance of Diversity. Eosinophil-Associated Ribonucleases. Structure and Function of Angiogenin. Antitumor Rnases. 2-5A-Dependent Rnase L: A Regulated Endoribonuclease in the Interferon System. RNA Processing Rnases in Mammalian Cells. Messenger RNA Ribonucleases and Mrna Turnover in Saccharomyces Cerevisae. Ribonuclease Inhibitor. Subject Index.
- Edition: 1
- Latest edition
- Published: February 11, 1997
- Language: English
JR
James F. Riordan
Affiliations and expertise
Harvard Medical School, Boston, Massachusetts, U.S.A.Read Ribonucleases on ScienceDirect