Retinoid Signaling Pathways
- 1st Edition, Volume 637 - April 29, 2020
- Editor: Ehmke Pohl
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 0 1 4 4 - 2
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 0 1 4 7 - 3
Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by le… Read more
Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Methods in Enzymology series
- Includes the latest information on retinoid signaling pathways
Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists
- Vitamin A and its natural derivatives
- Post-natal all-trans-retinoic acid biosynthesis
- Retinoid metabolism and functions mediated by retinoid binding-proteins
- Generation and isolation of recombinant retinoid oxidoreductase complex
- Sample preparation for structural and functional analyses of the STRA6 receptor for retinol-binding protein
- Use of fixatives for immunohistochemistry and their application for detection of retinoic acid synthesizing enzymes in the central nervous system
- Classical pathways of gene regulation by retinoids
- Protein-protein interactions in the regulation of RAR–RXR heterodimers transcriptional activity
- Natural ligands of RXR receptors
- DNA recognition by retinoic acid nuclear receptors
- Noncanonical retinoic acid signaling
- Retinoic acid and microRNA
- Analysis of vitamin A and retinoids in biological matrices
- Effects of vitamin A and retinoic acid on mouse embryonic stem cells and their differentiating progeny
- Identifying vitamin A signaling by visualizing gene and protein activity, and by biochemical isolation of vitamin A metabolites
- Whole mount in situ hybridization and immunohistochemistry for studying retinoic acid signaling in developing amphioxus
- Design of synthetic retinoids
- Application of human organotypic skin raft cultures for analysis of retinoid metabolism, retinoic acid signaling, and screening of bioactive rexinoids
- Tissue localization of retinoic acid receptor (RAR) active drugs
- The development of methodologies for high-throughput retinoic acid binding assays in drug discovery and beyond
- Using the human CYP26A1 gene promoter as a suitable tool for the determination of RAR-mediated retinoid activity
Chris P.F. Redfern
Joseph L. Napoli
Joseph L. Napoli and Hong Sik Yoo
Mark K. Adams, Olga V. Belyaeva and Natalia Y. Kedishvili
Brianna K. Costabile, Youn-Kyung Kim, Yunting Chen, Oliver B. Clarke, Loredana Quadro and Filippo Mancia
Azita Kouchmeshky and Peter McCaffery
Ehmke Pohl and Charles W.E. Tomlinson
Albane le Maire, Pierre Germain and William Bourguet
Patricia García, Paula Lorenzo and Angel R. de Lera
Carole Peluso-Iltis, Judit Osz and Natacha Rochel
Jennifer Nhieu, Yu-Lung Lin and Li-Na Wei
Lijun Wang, Atharva Piyush Rohatgi and Yu-Jui Yvonne Wan
Lindsay C. Czuba, Guo Zhong, King Yabut and Nina Isoherranen
Mary Ann Asson-Batres and Christopher W. Norwood
Stephen R. Shannon, Jianshi Yu, Amy E. Defnet, Danika Bongfeldt, Alexander R. Moise, Maureen A. Kane and Paul A. Trainor
Matteo Bozzo, Simona Candiani and Michael Schubert
David R. Chisholm and Andrew Whiting
Alla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili and Olga V. Belyaeva
Azita Kouchmeshky, Timothy Goodman, Andy Whiting and Peter McCaffery
Charles W.E. Tomlinson and Andrew Whiting
Reza Zolfaghari, Floyd J. Mattie, Cheng-Hsin Wei, David R. Chisholm, Andrew Whiting and A. Catharine Ross
- Edition: 1
- Volume: 637
- Published: April 29, 2020
- Language: English
EP
Ehmke Pohl
Ehmke Pohl is at Durham University, Durham, UK
Affiliations and expertise
Durham University, Durham, UKRead Retinoid Signaling Pathways on ScienceDirect