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Protein Modules and Protein-Protein Interactions

  • 1st Edition, Volume 61 - November 12, 2002
  • Latest edition
  • Editor: Joël Janin
  • Language: English

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein… Read more

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Description

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.

Key features

  • Comprehensive overview of different facets of macromolecule interactions
  • Computational and bioinformatics aspects of analyzing protein modules and their interactions
  • Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes

Readership

Biochemists, biophysicists, molecular biologists, immunologists

Table of contents

Protein Modules and Protein-Protein Interaction: Toward a Global View
Structural Basis for Affinity and Specificity in Macromolecular Recognition
Sequence Analysis of Multidomain Proteins: Past Perspectives and Future Directions
Identification of Transiently Interacting Proteins and of Stable Protein Complexes
Molecular Recognition in Antibody-Antigen Complexes Molecular Recognition by SH2 Domains
How SH3 Domains Recognize Proline
Structural Biology of eIF4F: mRNA Recognition and Preparation in Eukaryotic Translation Initiation

Review quotes

PRAISE FOR THE SERIES:
"The authority, originality, and editing of the reviews are first class." —NATURE

"The Advances in Protein Chemistry series has been a major factor in the education of protein chemists."—JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Product details

  • Edition: 1
  • Latest edition
  • Volume: 61
  • Published: November 12, 2002
  • Language: English

About the editor

JJ

Joël Janin

Affiliations and expertise
Laboratoire d'Enzymologie et Biochemie Structurales, France

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