Protein Interactions as Targets in Drug Discovery
- 1st Edition, Volume 121 - April 17, 2020
- Latest edition
- Editor: Rossen Donev
- Language: English
Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interacti… Read more
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Description
Description
Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interactions. Chapters in this new release include Trends in structure based drug design with protein targets, From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD), Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis, Aromatic-aromatic interactions in protein-drug and protein-protein interactions, Role of protein-protein interaction in allosteric drug design within the human methyltransferome, and much more.
Key features
Key features
- Integrates experimental and computational methods for studying protein interactions and their modulation by potential therapeutics
- Contains timely chapters written by well-renown authorities in their field
- Covers information that is well supported by a number of high quality illustrations, figures and tables
- Targets a very wide audience of specialists, researchers and students
Readership
Readership
This volume would be of great interest to a very wide audience - protein chemists, molecular cell biologists, immunologists, structural biologists, computational biochemists, medical doctors, pharmacologists and other researchers working in the field of protein interactions. Articles published here would also be of considerable benefit to medical, biology and pharmacology students specializing in this field
Table of contents
Table of contents
1. Latest trends in structure based drug design with protein targets
Angshuman Bagchi
2. From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD)
Stefano Moro
3. Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis
M. Michael Gromiha
4. Aromatic-aromatic interactions in protein-drug and protein-protein interactions
Adrian Gustavo Turjanski
5. Role of protein-protein interaction in allosteric drug design within the human methyltransferome
Guang Hu
6. Protein-Protein Interactions as the Basis for Cyclin-Dependent Kinase Inhibition
Mark Klein
7. Targeting FOXP3 complex ensemble in drug discovery
Bin Li
8. Targeting arrestin interactions with its partners for therapeutic purposes
Vsevolod V. Gurevich
9. Protein interactomics in kidney stone research
Visith Thongboonkerd
10. Human oral microbiome protein-protein interaction a cross-talk with health systemic implications
Marlene M.T. Barros
11. Protein-protein complexes as targets for drug discovery against infectious diseases
Yusuf Akhter
12. Therapeutic intervention of protein-protein interactions in innate immunity
Kevin J. Lumb
13. Physicochemical determinants of antibody-protein interactions
Sibel Kalyoncu Uzunlar
Product details
Product details
- Edition: 1
- Latest edition
- Volume: 121
- Published: April 18, 2020
- Language: English
About the editor
About the editor
RD