Progress in Medicinal Chemistry
- 1st Edition, Volume 42 - April 15, 2004
- Imprint: Elsevier
- Author: F.D. King
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 4 - 5 1 1 4 3 - 0
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 1 5 1 9 - 9
This volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of an… Read more
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Request a sales quoteThis volume includes information on recent advances in five important areas: an account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis; and a survey of semi-synthetic and totally synthetic antibiotics and anti-HIV agents and their sites of interaction; the development of inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) for the treatment of hypercholesterolemia; a description of recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action; and information on inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), (required for vital replication) as one of the most attractive targets for HCV infections.
- Edition: 1
- Volume: 42
- Published: April 15, 2004
- No. of pages (Hardback): 0
- Imprint: Elsevier
- Language: English
- Hardback ISBN: 9780444511430
- eBook ISBN: 9780080515199
FK
F.D. King
Affiliations and expertise
SmithKIine Beecham Pharmaceuticals
New Frontiers Science Park (North)
Third AvenueRead Progress in Medicinal Chemistry on ScienceDirect