Process Safety Management offers comprehensive and practical guidance for developing and implementing process safety in design, operations, and maintenance of existing facilities by the concepts of process safety management (PSM) through detailed definitions, examples, historic perspectives and case-studies related to process safety. This book is the natural successor to Sutton's 'Process Risk and Reliability Management' to offer updates and a deep dive into the crucial aspects of process safety. Across Twenty-Five Chapters, Process Safety Management provides guidance is provided for process safety elements, encompassing hazards analysis, incident investigation, operating procedures, training, and audits. The book outlines how to enhance safety but also emphasizes the improvement of operational integrity, equipment reliability, and system availability, with a focus on the integration of a process safety program into overall operational excellence. This book includes an overview of process safety regulations and standards, along with information on proposed updates to process safety standards by regulatory bodies such as OSHA and the EPA, while exploring how generative AI such as Chat GPT can be applied to PSM. Finally, this book includes discussion on net-zero initiatives and how process safety measures can be implemented to help work towards sustainable processes. This book will be a valuable resource for graduate students taking courses on process safety and risk engineering, such as courses are offered by Chemical Engineering; Industrial Engineering; and Process Engineering Disciplines. The book is also contains experimental guidance and will be very useful for practicing engineers in design house, consultancy, and operation. Process Safety Management will serve as reference book to develop, evaluate, and improve process safety management practices across multiple industries, and provide guidance to the members of regulatory agencies such as CSB, OSHA, API, NFPA, US EPA, and others.