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Principles and Applications of Molecular Diagnostics
- 1st Edition - June 13, 2018
- Editors: Nader Rifai, A. Rita Horvath, Carl T. Wittwer, Jason Park
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 6 0 6 1 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 6 0 6 2 - 6
Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis… Read more
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Request a sales quotePrinciples and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments.
- Explains the principles and tools of molecular biology
- Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results
- Provides a detailed description of current molecular applications used to solve diagnostics tasks
Chemists working in clinical laboratories (hospitals and commercial labs), pharmaceutical researchers, biotech researchers, government agencies (CDC, NIST, EPA) and standardization groups, forensic scientists and criminologists, biodefense and bioterrorism researchers, mass spec manufacturers
1. Principles of molecular biology
Howe
2. Genomes and variants
Wittwer, Park
3. Nucleic acid isolation
Thatcher
4. Nucleic acid techniques
Wittwer, Makrigiorgos
5. Molecular microbiology
Nolte
6. Genetics
Vnencak-Jones, Best
7. Solid tumor genomics
Mardis
8. Genetic aspects of hematopoietic malignancies
Kelley, Patel
9. Circulating tumor cells
Lianidou, Hoon
10. Circulating nucleic acids for prenatal diagnostics
Chiu, Lo
11. Pharmacogenetics
McMillin, Wadelius, Pratt
12. Identity testing
Weedn, Gettings, Podini
- No. of pages: 422
- Language: English
- Edition: 1
- Published: June 13, 2018
- Imprint: Elsevier
- Paperback ISBN: 9780128160619
- eBook ISBN: 9780128160626
NR
Nader Rifai
Affiliations and expertise
Professor Department of Pathology Harvard Medical School; The Louis Joseph Gay-Lussac Chair in Laboratory Medicine Boston Children's Hospital; Director of Clinical Chemistry Laboratory Medicine Boston Children's Hospital Boston, MassachusettsAH
A. Rita Horvath
Andrea Rita Horvath’s key research interests include evidence-based laboratory medicine (EBLM) including evidence-based monitoring, guideline development, and evaluation of new biomarkers and overdiagnosis. She holds advisory roles on test utilization and reimbursement policy at the National Prescribing Service of Australia and Medicare. She has published 160 research papers and 16 book chapters and has been an invited speaker at over 100 international conferences. Her national and international leadership positions include Chair of the IFCC Committee on EBLM (2003-2008); European Communities Confederation of Clinical Chemistry and Laboratory Medicine (EC4) Secretary (2005-2007); President of the Hungarian Society (2005-2008) and the Hungarian College of Laboratory Medicine (2008-2009); President-Elect (2007-2009), President (2009-2011) and Past President (2012-2013) of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM); chair of the EFLM working group on Test Evaluation (2011-2015) and member of the Board of Directors of the American Association of Clinical Chemistry (2014-2016).
Affiliations and expertise
Professor, School of Medical Sciences, University of New South Wales, Sydney, AustraliaCW
Carl T. Wittwer
Affiliations and expertise
Professor Emeritus,Pathology,University of Utah ,Salt Lake City, UtahJP
Jason Park
Affiliations and expertise
Associate Professor of Pathology, University of Texas Southwestern Medical Center
Director of Advanced Diagnostics Laboratory
Children’s Medical Center
Dallas, TX USARead Principles and Applications of Molecular Diagnostics on ScienceDirect