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Polymeric Materials for Biomedical Implants
Characterization, Properties, and Applications
- 1st Edition - October 3, 2023
- Editors: Sabu Thomas, Abhimanyu Tharayil
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 6 9 0 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 6 9 1 - 4
Polymeric Materials for Biomedical Implants: Characterization, Properties, and Applications offers a comprehensive guide to the various polymers utilized in the developme… Read more
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Request a sales quotePolymeric Materials for Biomedical Implants: Characterization, Properties, and Applications offers a comprehensive guide to the various polymers utilized in the development and application of biomedical implants. These materials possess unique properties which make them ideal for use in biomedical implants, including their high degree of flexibility, ease of fabrication, non-magnetic and radio transparent properties for medical imaging, and ease of engineering for biocompatibility. The book thoroughly reviews the properties, characterization and a broad range of applications of polymeric materials in biomedical implants, bringing all key information on this important topic together under a single reference.
The book's chapters cover vital topics for the development of polymeric biomedical implants, including biomaterial-tissue interactions, mechanical and surface property requirements for different implants, as well as market and ethical issues. This will be a useful reference for academics and researchers working in materials science, biomedical engineering, regenerative medicine and pharmacology, as well as R&D groups developing biomedical implants.
- Helps the reader make an informed choice when selecting polymeric materials for use in biomedical implants
- Covers a broad range of applications of biomedical implants, including cancer therapy, orthopedics, cardiovascular, biosensing and wound healing
- Emphasizes the importance of biocompatibility, with chapters covering toxicity and degradation aspects, as well as biomaterial-tissue interactions and the foreign body response
Researchers and academics in the fields of materials science, biomedical engineering, pharmacology and regenerative medicine, R&D groups developing biomedical implants
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter 1: Introduction to polymer materials for implants
- Abstract
- 1.1: Introduction
- 1.2: Polymers
- 1.3: Conclusion
- References
- Chapter 2: Characterization of polymer nanocomposites in biomedical implants
- Abstract
- 2.1: Introduction
- 2.2: Characterization techniques
- References
- Chapter 3: Polymer nanocomposites in biomedical implants
- Abstract
- 3.1: Introduction
- 3.2: Polymers
- 3.3: Nanocomposites
- 3.4: Fabrication
- 3.5: Application
- 3.6: Conclusion of studies
- References
- Chapter 4: Introduction to immune responses toward medical implants
- Abstract
- Graphical abstract
- 4.1: Introduction
- 4.2: Provisional matrix formation
- 4.3: Acute inflammation
- 4.4: Chronic inflammation
- 4.5: Conclusion
- References
- Chapter 5: Polymer implants for gene and drug delivery
- Abstract
- Acknowledgments
- 5.1: Introduction
- 5.2: Polymers in implantable drug/gene delivery systems
- 5.3: Biomedical applications of polymeric implants
- 5.4: Conclusion
- References
- Chapter 6: Polymers in wound dressing
- Abstract
- 6.1: Introduction
- 6.2: Polymers used in wound management
- 6.3: Physicochemical characterization and the biological studies
- 6.4: Conclusions and future trends
- References
- Chapter 7: Polymers as medical adhesives and sutures
- Abstract
- 7.1: Introduction
- 7.2: Polymer-based surgical sutures
- 7.3: Polymer-based tissue adhesives
- 7.4: Conclusion
- References
- Chapter 8: Polymeric nanoparticles in cancer therapy
- Abstract
- 8.1: Introduction
- 8.2: Polymeric nanoparticles in cancers
- 8.3: Challenges in polymeric nanoparticle-based cancer therapy
- 8.4: Regulatory issues
- 8.5: Clinical and preclinical studies
- 8.6: Conclusions
- References
- Chapter 9: Polymers in dentistry
- Abstract
- 9.1: Introduction
- 9.2: Polymers in dental adhesion
- 9.3: Restorative composite resin polymers
- 9.4: Denture base polymers
- 9.5: Polymers for treatment of dental caries
- 9.6: Polymers for assisted remineralization of carious dentin
- 9.7: Digital dentistry polymers
- 9.8: Conclusion
- References
- Chapter 10: Polymers for IOL systems
- Abstract
- 10.1: Introduction
- 10.2: Polymeric materials in IOL
- 10.3: Future perspective
- References
- Chapter 11: Polymer implants for cardiovascular application
- Abstract
- 11.1: Type of cardiovascular implants
- 11.2: Cardiovascular biomaterials
- 11.3: Risk factors for developing cardiovascular device-associated infections (CVDAI)
- 11.4: Microbial agents and pathogenesis in CVDAI
- 11.5: Biofilm
- 11.6: Microorganisms most commonly involved in CVDAI
- References
- Chapter 12: Polymers in maxillofacial prosthodontics
- Abstract
- 12.1: Introduction
- 12.2: History of maxillofacial prosthetic reconstruction
- 12.3: Maxillofacial materials
- 12.4: Testing procedures of silicone polymers
- 12.5: Digital maxillofacial prosthodontics
- References
- Chapter 13: Polymers for burn dressings and skin substitutes
- Abstract
- 13.1: Introduction
- 13.2: Nonpolymeric burn treatment
- 13.3: Polymers in burns wound dressings and skin substitutes
- 13.4: Conclusions
- References
- Chapter 14: Polymers for implantable bioartificial pancreas
- Abstract
- Acknowledgments
- Declaration of interests
- 14.1: Introduction
- 14.2: Polymers for fabricating a bioartificial pancreas
- 14.3: Functionalization of polymeric materials to boost bioactivity and biocompatibility
- 14.4: Different designs of polymeric constructs for a BAP
- 14.5: Conclusion
- References
- Chapter 15: Polymers and composites for peripheral nerve repair
- Abstract
- 15.1: Clinical challenge: Peripheral nerve injury (PNI)
- 15.2: Nerve anatomy and progression of PNI
- 15.3: PNI treatment strategies
- 15.4: Functional recovery of PNI
- 15.5: Conclusions
- References
- Chapter 16: Polymer interactions with blood
- Abstract
- 16.1: Introduction
- 16.2: Polymer-blood components interactions
- 16.3: Platelets
- 16.4: Plasma components
- 16.5: Architecture of polymers and effects on blood interactions
- 16.6: Specific blood compatibility tests
- 16.7: Nanofibers and microparticulate-type polymeric devices
- 16.8: Physicochemistry and degradability of polymers related to blood compatibility
- 16.9: Polymeric devices with increased blood compatibility
- 16.10: Final considerations
- References
- Chapter 17: Market access of implants: Regulatory framework and ethical issues
- Abstract
- 17.1: Introduction
- 17.2: Global regulatory framework
- 17.3: Market access of implants in the European Union
- 17.4: Market access of implants in the United States of America
- 17.5: Ethical issues of implants
- 17.6: Conclusions
- References
- Chapter 18: Additive manufacturing of polymeric implants
- Abstract
- 18.1: Introduction
- 18.2: Additive-manufactured implants
- 18.3: 3D Printing of bio-structures
- 18.4: Conclusions
- References
- Chapter 19: Strategies for the sterilization of polymeric biomaterials
- Abstract
- Acknowledgments
- 19.1: Introduction
- 19.2: Sterilization techniques
- 19.3: Sterilization of polymeric biomaterials
- 19.4: Supercritical CO2 sterilization
- References
- Chapter 20: Toxicity and degradation of polymeric implants
- Abstract
- 20.1: Introduction
- 20.2: Polymeric implants
- 20.3: Types of polymeric implants
- 20.4: Toxicity and degradation assessments of polymeric implants in different applications
- 20.5: Conclusion
- References
- Further reading
- Index
- No. of pages: 640
- Language: English
- Edition: 1
- Published: October 3, 2023
- Imprint: Woodhead Publishing
- Paperback ISBN: 9780323996907
- eBook ISBN: 9780323996914
ST
Sabu Thomas
Sabu Thomas is a Senior Professor of Mahatma Gandhi University, Kottayam, Kerala, India, and also Chairman of the TrEST Research Park, Trivandrum, India. He is known for his outstanding contributions in polymer science and nanotechnology.
Affiliations and expertise
Professor and Director, International and Interuniversity Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, IndiaAT
Abhimanyu Tharayil
Abhimanyu Tharayil completed his Ph. D from IIT Kanpur, India in the field of medical implants. Prior to his doctoral studies he worked on electrospinning of polymers in his Master’s. He has published research articles, review articles in peer reviewed journals and book chapters with reputed publishers. He has given invited lectures in the field of biomaterials and has conducted and attended conferences in that field. He is also an independent and certified operator of SEM, XRD, DMA, Micro injection molding, UTM, Electrospinning apparatus etc. He has served as the student president of Indian Institute of metals, Kanpur chapter during his doctoral studies. Presently, he is working as a researcher with Dr Sabu Thomas. His specialized areas of research are biomaterials for medical implants, polymer synthesis, polymer nanocomposites and electrospinning.
Affiliations and expertise
Postdoc Researcher, Mahatma Gandhi University, Kottayam, IndiaRead Polymeric Materials for Biomedical Implants on ScienceDirect