Plant-Based Drug Discovery
Unveiling Molecular Targets for Metabolic Conditions
- 1st Edition - September 1, 2025
- Imprint: Academic Press
- Editors: Mamta Bisht, Ajay Singh, Akhileshwar Kumar Srivastava
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 1 6 9 8 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 1 6 9 9 - 9
Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potent… Read more
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Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.
In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.
In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.
- Considers the therapeutic application of phytochemicals for the treatment of metabolic diseases, including cardiovascular disease, obesity, and type 2 diabetes
- Explores phytochemicals at the molecular level, covering signaling pathways of oxidative stress, mitophagy, inflammasomes, molecular chaperones, receptors, and how these mechanisms can be used to treat diseases
- Discusses the use of artificial intelligence and high-throughput omics technologies in plant-based drug discovery
Researchers and postgraduate/PhD students in the fields of molecular biology, biochemistry, pharmacology, phytochemistry, drug discovery, biotechnology and related fields
Section 1: Introduction
1. Overview of human metabolic diseases associated with lifestyle
Section 2: Phytochemicals and molecular targets
2. Significance of phytochemicals in metabolic disorders
3. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents
4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases
5. Plant‑derived bioactive peptides for treatment of metabolic disorders
6. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy
7. Phytochemicals as promising therapeutic approaches for inflammasome-related metabolic diseases
8. Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism
9. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailments
10. Molecular targets of plant nutraceuticals against obesity
11. Molecular insight to cure cardiovascular diseases through plants compounds
12. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus
Section 3: Nanotechnology methods
13. Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods
Section 4: Clinical study
14. Clinical evidences of phytochemicals in cure of metabolic diseases
Section 5: Technologies and challenges for plant-based drug discovery
15. Artificial intelligence in plant-based drug discovery against metabolic disorders
16. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases
17. Multi-targets drug design for screening of phytochemicals to cure of metabolic disorders
18. New opportunities and challenges for improving the druggability of plant product against metabolic disorders
1. Overview of human metabolic diseases associated with lifestyle
Section 2: Phytochemicals and molecular targets
2. Significance of phytochemicals in metabolic disorders
3. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents
4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases
5. Plant‑derived bioactive peptides for treatment of metabolic disorders
6. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy
7. Phytochemicals as promising therapeutic approaches for inflammasome-related metabolic diseases
8. Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism
9. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailments
10. Molecular targets of plant nutraceuticals against obesity
11. Molecular insight to cure cardiovascular diseases through plants compounds
12. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus
Section 3: Nanotechnology methods
13. Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods
Section 4: Clinical study
14. Clinical evidences of phytochemicals in cure of metabolic diseases
Section 5: Technologies and challenges for plant-based drug discovery
15. Artificial intelligence in plant-based drug discovery against metabolic disorders
16. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases
17. Multi-targets drug design for screening of phytochemicals to cure of metabolic disorders
18. New opportunities and challenges for improving the druggability of plant product against metabolic disorders
- Edition: 1
- Published: September 1, 2025
- Imprint: Academic Press
- Language: English
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Mamta Bisht
Dr. Mamta Bisht is presently working as an Assistant Professor in Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University (NAAC A+), Dehradun, Uttarakhand India. She is actively involved in the extraction, isolation, characterization of “Natural Products” obtained from the medicinal and aromatic plants with bioactivity since last 8 years. Besides this her analytical skill is in GC, GC-MS, HPLC, Prep- HPLC and HPTLC. Further, she is equally involved in the promotion of endangered and economically important species from the Youngest Himalayan region. She has been published more than fifteen papers in peer-reviewed international journal and seven book chapter. Further, she has been participated more than ten conferences including national and international. She is life time member of Indian Science Congress Association. Under her guidance many P.G. and U.G. student successfully completed her Project Thesis and some students are working with her. She is also guided the Ph. D students in the University.
Affiliations and expertise
Assistant Professor, Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University, Dehradun, Uttarakhand, IndiaAS
Ajay Singh
Prof (Dr.) Ajay Singh is currently working as Director SALS and Dean Research & Studies in Uttaranchal University, Dehradun, India. He has more than 20 years (including R&D industrial research) of research experience. He has published more than 70 research articles in reputed journals and several chapters during his research work. More than 5 patents and projects are also credited in his account. He has also written 2 academic books for UG and PG students. He has guided more than 50 students for Project thesis of U.G and P. G. students and awarded more than 5 Ph. D students and several are registered under him. He is the receipt of young Scientist award by Scientific Planet Society India and several other awards.
Affiliations and expertise
Professor and Dean, School of Applied and Life Sciences, Uttaranchal University, Dehradun, IndiaAS
Akhileshwar Kumar Srivastava
Dr. Mamta Bisht is presently working as an Assistant Professor in Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University (NAAC A+), Dehradun, Uttarakhand India. She is actively involved in the extraction, isolation, characterization of “Natural Products” obtained from the medicinal and aromatic plants with bioactivity since last 8 years. Besides this her analytical skill is in GC, GC-MS, HPLC, Prep- HPLC and HPTLC. Further, she is equally involved in the promotion of endangered and economically important species from the Youngest Himalayan region. She has been published more than fifteen papers in peer-reviewed international journal and seven book chapter. Further, she has been participated more than ten conferences including national and international. She is life time member of Indian Science Congress Association. Under her guidance many P.G. and U.G. student successfully completed her Project Thesis and some students are working with her. She is also guided the Ph. D students in the University.
Affiliations and expertise
CSIR-Central Food Technological Research Institute, Mysore, India