Pharmacology of Purine and Pyrimidine Receptors

1. The structure of the adenosine receptors: implications for drug discovery

J. Robert Lane, Veli-Pekka Jaakola, Adriaan P. IJzerman

2. Adenosine Receptors in Health and Disease

Stefania Gessi, Stefania Merighi, Katia Varani, and Pier Andrea Borea

3. Adenosine and the Regulation of Metabolism and Body Temperature

Bertil Fredholm, Stina M. Johansson and Ying-Qing Wang

4. Regulation of Leukocyte Function by Adenosine Receptors

Joel Linden

5. Role of Adenosine A2B Receptors in Inflammation

Igor Feoktistov and Italo Biaggioni

6. Interplay of Hypoxia and A2B Adenosine Receptors in Tissue Protection

Michael Koeppen, Tobias Eckle, and Holger Eltzschig

7. Allosteric Modulation of Purine and Pyrimidine Receptors

Kenneth Jacobson, Zhan-Guo Gao, Aniko Göblyös, and Adriaan IJzerman

8. Molecular Mechanisms of Purine and Pyrimidine Nucleotide Release

Eduardo R. Lazarowski, Juliana I. Sesma, Lucia Seminario-Vidal, and Silvia M. Kreda

9. Impact of Ectoenzymes on Purinergic Signalling

Filip Kukulski, Sébastien A. Lévesque, and Jean Sévigny

10. Ectonucleotidases as Regulators of Purinergic Signaling in Inflammation and Thrombosis

Simon C. Robson and Silvia Deaglio

11. P2X Receptors in Health and Disease

Geoffrey Burnstock and Charles Kennedy

12. Molecular Pharmacology, Physiology, and Structure of the P2Y Receptors

Ivar von Kügelgen and T. Kendall Harden²

13. P2Y Receptors in Health and Disease

David Erlinge

14. P2 Receptor Signaling in Neurons and Glia of the Central Nervous System

Laszlo Köles Anna Leichsenring, Patrizia Rubini and Peter Illes

15. Role of Purinergic Receptors in Neuroprotection

Tozaki-Saitoh Hidetoshi, Makoto Tsuda, and Kazuhide Inoue