Pesticides and Neurotoxicant Exposures
Impacts of Neurodevelopment and Long-Term Brain Health
- 1st Edition - May 1, 2026
- Latest edition
- Editors: Neha Gogia, Prasann Kumar
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 4 4 2 8 7 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 4 4 2 8 8 - 9
Neurotoxicity and Pesticide Exposure explores the neuroscience research revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive declin… Read more
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Neurotoxicity and Pesticide Exposure explores the neuroscience research revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive decline. This volume synthesizes findings on the mechanisms of pesticide-induced neurotoxicity and its impact on brain health. Targeted at researchers, clinicians, and policymakers, the book highlights gaps in knowledge and the urgent need for improved regulation to protect vulnerable populations. By bridging scientific insights with public health, it aims to advance understanding and prevention of pesticide-related neurological disorders.
- Identifies the link between pesticides and neurological disorders
- Explores research, risk assessment tools, and practical strategies for understanding, monitoring, and mitigating pesticides' neurotoxic effects
- Provide a comprehensive and interdisciplinary approach to understanding pesticides and neurotoxicity
- Offers case studies, relating scientific research to real world applications
Section 1: Introduction to Pesticides and Neurotoxicity
1. Pesticides and Human Health: An Overview
2. Neurotoxic Effects of Pesticides: Mechanisms and Pathways
3. Classification of Pesticides and Their Neurotoxic Potential
4. Routes of Pesticide Exposure and Bioaccumulation
5. Epidemiological Evidence of Pesticide-Induced Neurotoxicity
Section 2: Pesticides Classes and Their Neurotoxic Effects
6. Organophosphates and Acetylcholinesterase Inhibition
7. Carbamates: Mechanisms of Neurotoxicity
8. Organochlorines and Their Impact on the Nervous System
9. Pyrethroids: Effects on Ion Channels and Neurotransmission
10. Neonicotinoids and Their Influence on the Central Nervous System
11. Herbicides and Neurodegeneration: The Case of Paraquat and Glyphosate
12. Fungicides and Neurotoxicity: A Neglected Risk?
13. Rodenticides and Their Impact on Brain Function
14. Biopesticides: Safer Alternatives or Hidden Neurotoxins?
Section 3: Cellular and Molecular Mechanisms of Pesticide-Induced Neurotoxicity
15. Oxidative Stress, Reactive oxygen species and Mitochondrial Dysfunction in Pesticide Toxicity
16. Neuroinflammation and Glial Cell Activation in Pesticide Exposure
17. Neurotransmitter Dysregulation Induced by Pesticides
18. Epigenetic Modifications in Pesticide-Induced Neurotoxicity
19. Blood-Brain Barrier Disruption Mechanisms by Pesticides
20. Autophagy, Apoptosis, and Cell Death Pathways in Pesticide Toxicity
Section 4: Pesticides and Neurodevelopmental Disorders
21. Prenatal and Early-Life Pesticide Exposure: Impacts on Brain Development
22. Pesticides and Autism Spectrum Disorders: Evidence and Mechanisms
23. Attention Deficit Hyperactivity Disorder (ADHD) and Pesticide Exposure
24. Pesticides and Cognitive Impairments in Children
Section 5: Pesticides and Neurodegenerative Diseases
25. Pesticides and Alzheimer’s Disease: Risk Factors and Mechanisms
26. Parkinson’s Disease and Pesticide Exposure: A Strong Association?
27. Amyotrophic Lateral Sclerosis (ALS) and Neurotoxicity of Pesticides
28. Multiple Sclerosis and Pesticides: Possible Links
Section 6: Biomarkers and Detection of Pesticide-Induced Neurotoxicity
29. Biomarkers of Pesticide Exposure in the Nervous System
30. Neuroimaging, Computational and Artificial Intelligence Approaches in Pesticide Toxicity Assessment
31. Advances in Toxicogenomics for Evaluating Pesticide-Induced Neurotoxicity
Section 7: Mitigation Strategies and Future Directions
32. Precision agriculture and Artificial Intelligence driven pest management to reduce pesticide dependency
33. Detoxification Pathways and Neuroprotection Against Pesticides
34. Dietary and Nutritional Interventions for Reducing Neurotoxic Effects
35. Regulatory Policies and Risk Assessment of Neurotoxic Pesticides
36. Eco-Friendly Alternatives: Reducing the Neurotoxic Burden of Pesticides
37. Public Awareness and Education on Pesticide Neurotoxicity
38. Novel Therapeutic Strategies for Pesticide-Induced Neurotoxicity
39. Innovations in Pesticide Formulation for Reduced Neurotoxicity
40. Artificial Intelligence and Big Data in Neurotoxicology Research
41. Future Perspectives on Pesticide Use and Neurotoxic Risks
1. Pesticides and Human Health: An Overview
2. Neurotoxic Effects of Pesticides: Mechanisms and Pathways
3. Classification of Pesticides and Their Neurotoxic Potential
4. Routes of Pesticide Exposure and Bioaccumulation
5. Epidemiological Evidence of Pesticide-Induced Neurotoxicity
Section 2: Pesticides Classes and Their Neurotoxic Effects
6. Organophosphates and Acetylcholinesterase Inhibition
7. Carbamates: Mechanisms of Neurotoxicity
8. Organochlorines and Their Impact on the Nervous System
9. Pyrethroids: Effects on Ion Channels and Neurotransmission
10. Neonicotinoids and Their Influence on the Central Nervous System
11. Herbicides and Neurodegeneration: The Case of Paraquat and Glyphosate
12. Fungicides and Neurotoxicity: A Neglected Risk?
13. Rodenticides and Their Impact on Brain Function
14. Biopesticides: Safer Alternatives or Hidden Neurotoxins?
Section 3: Cellular and Molecular Mechanisms of Pesticide-Induced Neurotoxicity
15. Oxidative Stress, Reactive oxygen species and Mitochondrial Dysfunction in Pesticide Toxicity
16. Neuroinflammation and Glial Cell Activation in Pesticide Exposure
17. Neurotransmitter Dysregulation Induced by Pesticides
18. Epigenetic Modifications in Pesticide-Induced Neurotoxicity
19. Blood-Brain Barrier Disruption Mechanisms by Pesticides
20. Autophagy, Apoptosis, and Cell Death Pathways in Pesticide Toxicity
Section 4: Pesticides and Neurodevelopmental Disorders
21. Prenatal and Early-Life Pesticide Exposure: Impacts on Brain Development
22. Pesticides and Autism Spectrum Disorders: Evidence and Mechanisms
23. Attention Deficit Hyperactivity Disorder (ADHD) and Pesticide Exposure
24. Pesticides and Cognitive Impairments in Children
Section 5: Pesticides and Neurodegenerative Diseases
25. Pesticides and Alzheimer’s Disease: Risk Factors and Mechanisms
26. Parkinson’s Disease and Pesticide Exposure: A Strong Association?
27. Amyotrophic Lateral Sclerosis (ALS) and Neurotoxicity of Pesticides
28. Multiple Sclerosis and Pesticides: Possible Links
Section 6: Biomarkers and Detection of Pesticide-Induced Neurotoxicity
29. Biomarkers of Pesticide Exposure in the Nervous System
30. Neuroimaging, Computational and Artificial Intelligence Approaches in Pesticide Toxicity Assessment
31. Advances in Toxicogenomics for Evaluating Pesticide-Induced Neurotoxicity
Section 7: Mitigation Strategies and Future Directions
32. Precision agriculture and Artificial Intelligence driven pest management to reduce pesticide dependency
33. Detoxification Pathways and Neuroprotection Against Pesticides
34. Dietary and Nutritional Interventions for Reducing Neurotoxic Effects
35. Regulatory Policies and Risk Assessment of Neurotoxic Pesticides
36. Eco-Friendly Alternatives: Reducing the Neurotoxic Burden of Pesticides
37. Public Awareness and Education on Pesticide Neurotoxicity
38. Novel Therapeutic Strategies for Pesticide-Induced Neurotoxicity
39. Innovations in Pesticide Formulation for Reduced Neurotoxicity
40. Artificial Intelligence and Big Data in Neurotoxicology Research
41. Future Perspectives on Pesticide Use and Neurotoxic Risks
- Edition: 1
- Latest edition
- Published: May 1, 2026
- Language: English
NG
Neha Gogia
Dr. Gogia is a Post-Doctoral Associate at Yale. Having completed her PhD degree at the University of Dayton, and Cornell University’s International Agriculture and Rural Development Program (IARD) she was awarded the Gerald L. Willis Award of Excellence for Outstanding Teaching in 2019. Her current work focuses on understanding cellular and molecular mechanisms underlying polyglutamine diseases, namely the identification and validation of genetic modifiers which can serve as potential therapeutic targets and can ameliorate the onset or progression of neurodegenerative diseases.
Affiliations and expertise
Post-Doctoral Associate, Yale University, Connecticut, USAPK
Prasann Kumar
Dr. Prasann Kumar, assistant professor cum research intensive faculty in the
Department of Agronomy, School of Agricultural (ICAR-Accredited), Lovely
Professional University, Punjab, specializes in stress physiology, plant tissue culture,
physiology of plantmicrobe/pathogen interaction, and biodiversity management.
Dr. Kumar has completed the International Agricultural Rural Development
Programme from Cornell University, Ithaca, New York, United States. He has
received a doctorate from Banaras Hindu University, Varanasi. He also has
authored 40 books published by national and international publishers, which find
a place in national as well as various Overseas Institutions’ libraries. He has
guided 19 MSc students for their thesis.
Affiliations and expertise
Assistant Professor, Department of Agronomy, School of Agricultural (ICAR-Accredited), Lovely Professional University, Punjab, India