Pediatric Gastrointestinal and Liver Disease
- 7th Edition - June 11, 2025
- Editors: Robert Wyllie, Jeffrey S. Hyams, Marsha Kay
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 6 0 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 9 1 - 6
Accessible, practical, and focused on diagnosis and treatment, Pediatric Gastrointestinal and Liver Disease, Seventh Edition, covers the entire spectrum of pediatric GI, hepatic,… Read more
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Accessible, practical, and focused on diagnosis and treatment, Pediatric Gastrointestinal and Liver Disease, Seventh Edition, covers the entire spectrum of pediatric GI, hepatic, and nutritional disorders. This popular reference offers definitive guidance from experienced editors Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay, as well as globally renowned contributors who share their knowledge and expertise on complex issues. Full-color illustrations, review questions online, real-world case studies, and detailed instruction on performing key procedures ensure that this updated edition remains your reference of choice in this fast-changing area.
- Includes significantly updated coverage of the gut microbiome; new biologic therapies for the treatment of pediatric inflammatory bowel diseases; advancements in the treatment of pediatric liver diseases, including metabolic-associated fatty liver disease (MAFLD); and new diagnostic imaging techniques
- Features a robust art program with full-color anatomical figures, clinical photos, and other illustrations throughout the text
- Details key procedures such as esophagogastroduodenoscopy and related techniques; colonoscopy and polypectomy; endoscopic retrograde cholangiopancreatography and endoscopic ultrasound; capsule endoscopy and small bowel enteroscopy; GI motility procedures; and more
- Prepares you for certification and recertification with more than 400 board-style review questions, answers, and rationales online
- Contains numerous algorithms that provide quick and easy retrieval of diagnostic, screening, and treatment information, as well as detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes
- An ideal everyday resource for pediatric gastroenterologists and hepatologists, pediatric dieticians and nutritionists, pediatricians, family medicine practitioners, PAs, and NPs
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Pediatric Gastroenterologists and Hepatologists. Pediatric Nutritionists
SECTION 1 Biologic Aspects of Gastrointestinal Function
1 Development of the Gastrointestinal Tract
2 Basic Aspects of Digestion and Absorption
3 Bile Acid Physiology and Alterations in the Enterohepatic Circulation
4 The Gut Microbiome in Pediatrics
SECTION 2 Clinical Problems
5 Gastrointestinal Mucosal Immunology and Mechanisms of Inflammation
6 Chronic Abdominal Pain of Childhood and Adolescence
7 Approach to the Child With a Disorder of Gut-Brain Interaction
8 Vomiting and Nausea
9 Diarrhea
10 Colic and Gastrointestinal Gas
11 Functional Constipation and Fecal Incontinence
12 Growth Faltering (Failure to Thrive)
13 Gastrointestinal Hemorrhage
14 Obesity
15 Eating Disorders in Children and Adolescents
16 Jaundice: Unconjugated Hyperbilirubinemia
17 Ascites
18 Caustic Ingestion and Foreign Bodies
SECTION 3 The Esophagus
19 Developmental Anatomy and Physiology of the Esophagus
20 Congenital Malformations of the Esophagus
21 Gastroesophageal Reflux
22 Achalasia and Other Motor Disorders
23 Other Diseases of the Esophagus
SECTION 4 The Stomach
24 Developmental Anatomy and Physiology of the Stomach
25 Congenital Anomalies and Surgical Disorders of the Stomach
26 Gastritis, Gastropathy, and Ulcer Disease
27 Helicobacter pylori in Childhood
28 Gastric Motility Disorders
29 Bezoars
SECTION 5 The Small and Large Intestine
30 Anatomy and Physiology of the Small and Large Intestines
31 Maldigestion and Malabsorption
32 Protracted Diarrhea
33 Protein-Losing Enteropathy
34 Celiac Disease
35 Short Bowel Syndrome
36 Surgical Management of Pediatric Gut Failure: Decades of Innovation and Integration With Rewarding Long-Term Outcomes
37 Allergic and Eosinophilic Gastrointestinal Disease
38 Infectious Diarrhea
39 Enteric Parasites
40 Gastrointestinal Manifestations of Immunodeficiency
41 Pediatric Polyposis Syndromes
42 Crohn’s Disease
43 Ulcerative Colitis in Children and Adolescents
44 Chronic Intestinal Pseudo-Obstruction
45 Neonatal Necrotizing Enterocolitis
46 Disorders of the Anorectum Fissures, Fistulas, Prolapse, Hemorrhoids, Tags
47 Neoplasms of the Gastrointestinal Tract
48 Neoplasms of the Liver
49 Other Diseases of the Small Intestine and Colon
50 Appendicitis
SECTION 6 Pediatric Surgical Disorders
51 Intussusception in Infants and Children
52 Inguinal Hernias and Hydroceles
53 Meckel Diverticula and Omphalomesenteric Duct Remnants
54 Hirschsprung Disease
55 Imperforate Anus
56 Abnormal Rotation and Fixation of the Intestine
57 Small and Large Bowel Stenosis and Atresias
58 Newborn Abdominal Wall Defects
59 Gastrostomy, Jejunostomy, and Stomas of the Small and Large Intestine
SECTION 7 Gastrointestinal Procedures
60 Esophagogastroduodenoscopy and Related Techniques
61 Colonoscopy, Polypectomy, and Related Techniques
62 Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound
63 Capsule Endoscopy and Small Bowel Enteroscopy
64 Gastrointestinal Motility Procedures
65 Gastrointestinal Pathology
66 Liver Pathology
67 Anesthesia and Sedation for Pediatric Gastroenterology Procedures and Patients
SECTION 8 The Liver and Bile Ducts
68 Structural and Functional Development of the Hepatobiliary System
69 Neonatal Hepatitis
70 Biliary Atresia and Neonatal Disorders of the Bile Ducts
71 Pediatric Cholestatic Liver Disease
72 Mitochondrial Hepatopathies: Disorders of Fatty Acid Oxidation and the Respiratory Chain
73 Abnormalities of Hepatic Protein Metabolism
74 Abnormalities of Carbohydrate Metabolism and the Liver
75 Nonalcoholic Fatty Liver Disease
76 Acute and Chronic Hepatitis
77 Portal Hypertension
78 Liver Failure
79 Liver Transplantation in Children
80 Diseases of the Gallbladder
SECTION 9 The Pancreas
81 Pancreatic Development
82 Cystic Fibrosis and Congenital Anomalies of the Exocrine Pancreas
83 Pancreatitis
84 Total Pancreatectomy With Islet Autotransplantation
85 Pancreatic Neuroendocrine Tumors
SECTION 10 Nutrition
86 Infant and Toddler Nutrition
87 Nutritional Assessment
88 Tubes for Enteric Access
89 Parenteral Nutrition
90 Enteral Nutrition
91 Management of Diarrhea
92 Effects of Digestive Diseases on Bone Metabolism
93 Nutrition and Feeding for Children With Developmental Disabilities
94 Fecal Transplant
1 Development of the Gastrointestinal Tract
2 Basic Aspects of Digestion and Absorption
3 Bile Acid Physiology and Alterations in the Enterohepatic Circulation
4 The Gut Microbiome in Pediatrics
SECTION 2 Clinical Problems
5 Gastrointestinal Mucosal Immunology and Mechanisms of Inflammation
6 Chronic Abdominal Pain of Childhood and Adolescence
7 Approach to the Child With a Disorder of Gut-Brain Interaction
8 Vomiting and Nausea
9 Diarrhea
10 Colic and Gastrointestinal Gas
11 Functional Constipation and Fecal Incontinence
12 Growth Faltering (Failure to Thrive)
13 Gastrointestinal Hemorrhage
14 Obesity
15 Eating Disorders in Children and Adolescents
16 Jaundice: Unconjugated Hyperbilirubinemia
17 Ascites
18 Caustic Ingestion and Foreign Bodies
SECTION 3 The Esophagus
19 Developmental Anatomy and Physiology of the Esophagus
20 Congenital Malformations of the Esophagus
21 Gastroesophageal Reflux
22 Achalasia and Other Motor Disorders
23 Other Diseases of the Esophagus
SECTION 4 The Stomach
24 Developmental Anatomy and Physiology of the Stomach
25 Congenital Anomalies and Surgical Disorders of the Stomach
26 Gastritis, Gastropathy, and Ulcer Disease
27 Helicobacter pylori in Childhood
28 Gastric Motility Disorders
29 Bezoars
SECTION 5 The Small and Large Intestine
30 Anatomy and Physiology of the Small and Large Intestines
31 Maldigestion and Malabsorption
32 Protracted Diarrhea
33 Protein-Losing Enteropathy
34 Celiac Disease
35 Short Bowel Syndrome
36 Surgical Management of Pediatric Gut Failure: Decades of Innovation and Integration With Rewarding Long-Term Outcomes
37 Allergic and Eosinophilic Gastrointestinal Disease
38 Infectious Diarrhea
39 Enteric Parasites
40 Gastrointestinal Manifestations of Immunodeficiency
41 Pediatric Polyposis Syndromes
42 Crohn’s Disease
43 Ulcerative Colitis in Children and Adolescents
44 Chronic Intestinal Pseudo-Obstruction
45 Neonatal Necrotizing Enterocolitis
46 Disorders of the Anorectum Fissures, Fistulas, Prolapse, Hemorrhoids, Tags
47 Neoplasms of the Gastrointestinal Tract
48 Neoplasms of the Liver
49 Other Diseases of the Small Intestine and Colon
50 Appendicitis
SECTION 6 Pediatric Surgical Disorders
51 Intussusception in Infants and Children
52 Inguinal Hernias and Hydroceles
53 Meckel Diverticula and Omphalomesenteric Duct Remnants
54 Hirschsprung Disease
55 Imperforate Anus
56 Abnormal Rotation and Fixation of the Intestine
57 Small and Large Bowel Stenosis and Atresias
58 Newborn Abdominal Wall Defects
59 Gastrostomy, Jejunostomy, and Stomas of the Small and Large Intestine
SECTION 7 Gastrointestinal Procedures
60 Esophagogastroduodenoscopy and Related Techniques
61 Colonoscopy, Polypectomy, and Related Techniques
62 Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound
63 Capsule Endoscopy and Small Bowel Enteroscopy
64 Gastrointestinal Motility Procedures
65 Gastrointestinal Pathology
66 Liver Pathology
67 Anesthesia and Sedation for Pediatric Gastroenterology Procedures and Patients
SECTION 8 The Liver and Bile Ducts
68 Structural and Functional Development of the Hepatobiliary System
69 Neonatal Hepatitis
70 Biliary Atresia and Neonatal Disorders of the Bile Ducts
71 Pediatric Cholestatic Liver Disease
72 Mitochondrial Hepatopathies: Disorders of Fatty Acid Oxidation and the Respiratory Chain
73 Abnormalities of Hepatic Protein Metabolism
74 Abnormalities of Carbohydrate Metabolism and the Liver
75 Nonalcoholic Fatty Liver Disease
76 Acute and Chronic Hepatitis
77 Portal Hypertension
78 Liver Failure
79 Liver Transplantation in Children
80 Diseases of the Gallbladder
SECTION 9 The Pancreas
81 Pancreatic Development
82 Cystic Fibrosis and Congenital Anomalies of the Exocrine Pancreas
83 Pancreatitis
84 Total Pancreatectomy With Islet Autotransplantation
85 Pancreatic Neuroendocrine Tumors
SECTION 10 Nutrition
86 Infant and Toddler Nutrition
87 Nutritional Assessment
88 Tubes for Enteric Access
89 Parenteral Nutrition
90 Enteral Nutrition
91 Management of Diarrhea
92 Effects of Digestive Diseases on Bone Metabolism
93 Nutrition and Feeding for Children With Developmental Disabilities
94 Fecal Transplant
- Edition: 7
- Published: June 11, 2025
- Language: English
RW
Robert Wyllie
Robert Wyllie is Chief of Medical Operations, Associate Chief of Staff at Cleveland Clinic, Professor of Pediatrics, Lerner College of Medicine at Case Western Reserve University, Cleveland, Ohio.
Affiliations and expertise
Chief of Medical Operations, Associate Chief of Staff, Cleveland Clinic, Professor of Pediatrics, Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, USAJH
Jeffrey S. Hyams
Jeffrey S. Hyams is Head, Division of Digestive Diseases, Hepatology, and Nutrition at Connecticut Children's Medical Center, Hartford, Connecticut; Professor of Pediatrics at University of Connecticut School of Medicine, Farmington, Connecticut.
Affiliations and expertise
Head, Division of Digestive Diseases, Hepatology, and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut; Professor of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut, USAMK
Marsha Kay
Marsha Kay is Chair in the Department of Pediatric Gastroenterology and Nutrition, Director, Pediatric Endoscopy at Cleveland Clinic Children’s Hospital, Cleveland, Ohio.
Affiliations and expertise
Chair, Department of Pediatric Gastroenterology and Nutrition, Director, Pediatric Endoscopy, Cleveland Clinic Children’s Hospital, Cleveland, Ohio, USARead Pediatric Gastrointestinal and Liver Disease on ScienceDirect