Pediatric Bone
Biology and Diseases
- 3rd Edition - November 1, 2029
- Latest edition
- Editors: Francis H. Glorieux, John M. Pettifor
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 5 3 8 7 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 5 3 8 8 - 8
Pediatric Bone, Third Edition illustrates how bone mass attained in childhood and adolescence is an important determinant of lifelong skeletal health. The health habits formed in… Read more
Purchase options
Pediatric Bone, Third Edition illustrates how bone mass attained in childhood and adolescence is an important determinant of lifelong skeletal health. The health habits formed in childhood can make, or literally break, bones as the skeleton ages. Since the publication of the second edition, advances continue to be made in our understanding of the mechanisms and factors controlling the growth and development of bone. The use of novel non-invasive imaging modalities has also become more widespread, giving researchers and clinicians a more comprehensive understanding of the growing skeleton. The third edition expands on the already broad coverage of bone physiology, mineral homeostasis, and pathophysiological development of bone diseases.
Researchers in all areas bone biology, physiology, and biochemistry will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays. For those clinical researchers who are also MDs, correct diagnosis - and therefore correct treatment - of bone diseases depends on a strong understanding of the molecular basis for the disease.
- Deals exclusively with bone development and diseases of children and each chapter written by a leader in the field
- Fully referenced with hundreds of references per chapter, along with nearly 300 figures, over 100 x-rays, and many helpful tables
- Provides a common language for bone biologists, pediatricians, rheumatologists, and orthopedic surgeons to discuss the development of bone cells and their interactions in the development of pediatric disease
Biomedical researchers, research clinicians, graduate students, and fellows in the fields of endocrinology, bone biology, osteology, and rheumatology
1. Bone Cell Biology: Osteoclasts, Osteoblasts, Osteocytes
2. Bone Matrix and Mineralization
3. Prenatal Bone Development
4. Postnatal Bone Growth: Growth Plate Biology, Bone Formation, and Remodeling
5. Dental Development and Maturation, from the Dental Crypt to the Final Occlusion
6. Parathyroid Hormone and Calcium Homeostasis
7. Phosphate Homeostasis Regulatory Mechanisms
8. Vitamin D Biology
9. Peak Bone Mass and Its Regulation
10. Pregnancy and Lactation
11. Fetal Mineral Homeostasis
12. Radiology
13. Non-invasive Techniques for Bone Mass Measurement
14. Assessment of Maturation: Bone Age and Pubertal Assessment
15. Biochemical Markers of Bone Meabolism
16. Pediatric Bone Histomorphometry
17. A Diagnostic Approach to Skeletal Dysplasias
18. The Spectrum of Pediatric Osteoporosis
19. Osteogenesis Imperfecta
20. Sclerosing Bone Dysplasias
21. Parathyroid Disorders
22. Fibrous Dysplasia
23. Nutritional Rickets
24. Metabolic Bone Disease in the Neonatal Period and its Later Sequelae
25. Rickets Due to Hereditary Abnormalities of Vitamin D Synthesis or Action
26. Familial Hypophosphatemia and Related Disorders
27. Hereditary Tubular Disorders of Mineral Handling
28. Hypophosphatasia
29. Chronic Kidney Disease Mineral and Bone Disorder
30. Extraskeletal Bone Formation
- Edition: 3
- Latest edition
- Published: November 1, 2029
- Language: English
FG
Francis H. Glorieux
Affiliations and expertise
Professor of Surgery, Pediatrics and Human Genetics, McGill University; Adjunct Professor of Pediatrics, University of Montreal; Director of Research, Shriners Hospital for Children, Montreal, QC CanadaJP
John M. Pettifor
Affiliations and expertise
Honorary Professorial Researcher and Clinical Professor, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa