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Pancreatic Disease, An Issue of Gastroenterology Clinics of North America
- 1st Edition, Volume 54-1 - February 1, 2025
- Editor: Guru Trikudanathan
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 7 9 4 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 7 9 5 - 3
In this issue of Gastroenterology Clinics, guest editor Dr. Guru Trikudanathan brings his considerable expertise to the topic of Pancreatic Disease. Top multidiscipli… Read more
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Request a sales quoteIn this issue of Gastroenterology Clinics, guest editor Dr. Guru Trikudanathan brings his considerable expertise to the topic of Pancreatic Disease. Top multidisciplinary experts provide state-of-the-art information on the advances in the diagnosis and management of acute pancreatitis, autoimmune pancreatitis, pancreatic cysts, surgical and endoscopic step-up approaches to necrotizing pancreatitis, and much more.
- Contains 14 relevant, practice-oriented topics, including organ failure and prediction of severity in acute pancreatitis; clinical and investigative approach to recurrent acute pancreatitis; management of pancreatic duct leak, strictures, and disconnected pancreatic duct syndrome; pathophysiology, assessment, and management of pain associated with chronic pancreatitis; early detection and screening for pancreatic cancer; and more
- Provides in-depth clinical reviews on pancreatic disease, offering actionable insights for clinical practice
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Gastroenterologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- Organ Failure and Prediction of Severity in Acute Pancreatitis
- Key points
- Introduction
- Definition of organ failure
- Characterization of organ failure in acute pancreatitis
- Prediction of severity of the disease
- Pathophysiology of organ failure
- Organ failure type, clinical trajectory, and implication for management
- Organ failure and its impact on mortality
- Treatment of organ failure and future direction
- Clinics care points
- Supplementary data
- Initial Management of Acute Pancreatitis
- Key points
- Introduction
- Early prognosis
- Fluid resuscitation
- Management of symptoms
- Nutrition
- Antibiotics and antifungal therapy
- Endoscopic retrograde cholangiopancreatography
- Etiology assessment
- Summary
- Clinics care points
- Endoscopic Step-Up Approach in Management of Necrotizing Pancreatitis
- Key points
- Introduction
- Concept and evolution of step-up approach
- Step-up approach
- “Endoscopic step-up approach” versus “surgical step-up approach”
- Endoscopic step-up approach
- Step 1: EUS-guided drainage of pancreatic fluid collection
- Step 2: direct endoscopic necrosectomy (DEN)
- Step 3: additional sessions of direct endoscopic necrosectomy (DEN)
- Step 4: per-cutaneous drainage (PCD) or surgery
- Step-up approach versus primary DEN
- Summary
- Clinics care points
- Surgical Step-Up Approach in Management of Necrotizing Pancreatitis
- Key points
- Introduction
- Incidence and etiology
- Pathophysiology and treatment considerations
- Definitions
- Clinical course
- Intervention in necrotizing pancreatitis
- Timing of cholecystectomy
- Outcomes including long-term sequelae
- Summary
- Clinics care points
- Management of Pancreatic Duct Strictures, Leaks, and Disconnected Pancreatic Duct Syndrome
- Key points
- Pancreatic duct stricture
- Pancreatic duct leaks
- Disconnected pancreatic duct syndrome
- Summary
- Clinics care points
- Updates in Post–Endoscopic Retrograde Cholangiopancreatography Pancreatitis
- Key points
- Introduction
- Pathogenesis of post–endoscopic retrograde cholangiopancreatography pancreatitis
- Definition of post–endoscopic retrograde cholangiopancreatography pancreatitis
- Risk factors of post–endoscopic retrograde cholangiopancreatography pancreatitis
- Prevention of post–endoscopic retrograde cholangiopancreatography pancreatitis
- Endoscopic techniques
- Summary
- Clinics care points
- Funding
- Clinical and Investigative Approach to Recurrent Acute Pancreatitis
- Key points
- Introduction
- Pathogenesis of acute pancreatitis recurrence
- Etiology
- Evaluation
- Endoscopic sphincterotomy for recurrent acute pancreatitis
- Future directions
- Summary
- Clinics care points
- Pathophysiology, Assessment, and Management of Pain Associated with Chronic Pancreatitis
- Key points
- Introduction
- Pathophysiology of pancreatic pain
- Pain assessment
- Pain management
- Pharmacologic treatments
- Interventional therapy
- Experimental treatment
- Summary
- Clinics care points
- Updates in the Diagnosis of Chronic Pancreatitis: Current Approaches and New Possibilities
- Key points
- Introduction and background
- Advances in diagnostic approaches
- Summary
- Clinics care points
- Updates in the Management of Chronic Pancreatitis: Navigating Through Recent Advances
- Key points
- Introduction and background
- Updates in management strategies
- Summary
- Clinics care points
- Risk Factors and Mechanisms for Diabetes in Pancreatitis
- Key points
- The scope of the problem: diabetes is a common complication of pancreatitis, often underrecognized, and underdiagnosed
- Mechanisms underlying the development of diabetes
- Risk factors for diabetes in acute and chronic pancreatitis
- Management and treatment of diabetes mellitus
- Diabetes in children with pancreatitis
- Summary
- Clinics care points
- What Is the Latest in Pancreatic Cysts?
- Key points
- Introduction
- Approach to pancreatic cysts
- Endoscopic ultrasound, carcinoembryonic antigen, and cytology in the diagnosis of a pancreatic cyst
- Contrast-enhanced endoscopic ultrasound
- Role of through-the-needle biopsy forceps
- Needle confocal laser endomicroscopy
- Cyst fluid molecular markers
- Endoscopic ultrasound–fine needle aspiration and antibiotics
- Pancreatic cyst management: data on ablation
- Pancreatic cyst management: stopping surveillance
- Pancreatic cyst management: the newest guidelines
- Postsurgical surveillance
- Impact of family history or germline genetic mutations on surveillance
- Summary
- Clinics care points
- Pancreatic Cancer: Screening and Early Detection
- Key points
- Introduction
- High-risk groups
- How do screening principles apply to pancreatic cancer?
- Current recommendations
- Future directions
- Summary
- Clinics care points
- Updates in the Surgical Management of Pancreatic Ductal Adenocarcinoma
- Key points
- Introduction
- Patient selection for surgical management
- Determining resectability
- Current perspectives on chemotherapy, radiation, and the timing of surgery
- Updates in surgical technique and considerations
- Post-surgical management
- Summary
- Clinics care points
- What Is the Latest in Autoimmune Pancreatitis
- Key points
- Introduction
- Clinical presentation, imaging features, and histology
- Medical management of autoimmune pancreatitis
- Future directions
- Summary
- Clinics care points
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 54-1
- Published: February 1, 2025
- Imprint: Elsevier
- Hardback ISBN: 9780443297946
- eBook ISBN: 9780443297953
GT
Guru Trikudanathan
Affiliations and expertise
Associate Professor of Medicine Division of Gastroenterology, Hepatology and Nutrition Section Lead, Advanced Endoscopy University of Minnesota Minneapolis, MN, USA