Oxidative Stress and Dietary Antioxidants in Neurological Diseases

1st Edition - June 11, 2020
Editors: Colin R Martin, Victor R Preedy
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 7 8 0 - 8
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 1 7 7 8 1 - 5

Oxidative Stress and Dietary Antioxidants in Neurological Diseases provides an overview of oxidative stress in neurological diseases and associated conditions, including behaviora… Read more

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Oxidative Stress and Dietary Antioxidants in Neurological Diseases provides an overview of oxidative stress in neurological diseases and associated conditions, including behavioral aspects and the potentially therapeutic usage of natural antioxidants in the diet. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. The book examines basic processes of oxidative stress—from molecular biology to whole organs—relative to cellular defense systems, and across a range of neurological diseases.

Sections discuss antioxidants in foods, including plants and components of the diet, examining the underlying mechanisms associated with therapeutic potential and clinical applications. Although some of this material is exploratory or preclinical, it can provide the framework for further in-depth analysis or studies via well-designed clinical trials or the analysis of pathways, mechanisms, and components in order to devise new therapeutic strategies. Very often oxidative stress is a feature of neurological disease and associated conditions which either centers on or around molecular and cellular processes. Oxidative stress can also arise due to nutritional imbalance during a spectrum of timeframes before the onset of disease or during its development.

ForewordUna Macleod

Part I: Oxidative stress and neurological diseases

1. The role of reactive oxygen species in the pathogenic pathways of depressionMasakazu Ibi and Chihiro Yabe-Nishimura

2. The relationship between the blood-brain barrier, degenerative neuropathy, and oxidative stressDavid Fisher and Olufemi A. Alamu

3. Neuroinflammatory processes and oxidative stressTameka A. Clemons, Na’Taki Osborne Jelks, L. Monique Vance, and Kimberly Williams

4. Revisiting the oxidative stress theory of aging: Molecular mechanisms underlying brain agingJoana C. d’Avila

5. Neuroblastoma and oxidative stress: From pathogenesis to in vitro models of neurodegenerationAnthea Di Rita and Flavie Strappazzon

6. Oxidative stress in epileptogenesis: Febrile seizures, chemoconvulsant pilocarpine, and electrical stimulationDavid Agustin León Navarro, María Crespo, and Mairena Martín

7. DJ-1 in astrocytic neuroprotection to oxidative stressAmanda J. Edson, Helena A. Hushagen, and Kari E. Fladmark

8. Oxidative stress markers in seizures and epilepsy: Methods and applications to modelsLaura Medina-Ceja, Kenia Pardo-Peña, and Alberto Morales-Villagrán

Part II: Antioxidants and neurological diseases

9. Antioxidant therapy, oxidative stress, and blood-brain barrier: The road of dietary antioxidantsMiguel Pinto, Sofia Benfeito, Carlos Fernandes, and Fernanda Borges

10. Antioxidant and neuroprotective properties of Mediterranean oils: Argan oil, olive oil, and milk thistle seed oilAsmaa Badreddine, Amira Zarrouk, Wiem Meddeb, Thomas Nury, Leila Rezig, Meryam Debbabi, Fatima Zohra Bessam, Fatiha Brahmi, Anne Vejux, Mondher Mejri, Boubker Nasser, and Gérard Lizard

11. Aromatic plants: A source of compounds with antioxidant and neuroprotective effectsSandra Gonc¸alves, Inês Mansinhos, and Anabela Romano

12. The elderly, use of antioxidants and memoryWilliam K. Summers

13. Aspidosperma pyrifolium Mart. antioxidants features and neuronal tissuesDayane Pessoa de Araújo and Glauce Socorro de Barros Viana

14. Berberine neuroprotection and antioxidant activityMohsen Imenshahidi and Hossein Hosseinzadeh

15. Carnosic acid and carnosol: Neuroprotection and the mitochondriaMarcos Roberto de Oliveira

16. Coconut oil and antioxidative neuroprotectionSiong Meng Lim, Nur Syafiqah Rahim, and Kalavathy Ramasamy

17. Antioxidant effects of Curcuma longa and its active constituent, curcumin, for the therapy of neurological disordersBibi Marjan Razavi and Hossein Hosseinzadeh

18. Neuroprotective mechanisms of Ginkgo biloba against oxidative stressHoi Man Cheung and David Tai Wai Yew

19. Morinda citrifolia Linn. (Noni) fruit, antioxidant effects, and neuroprotectionVijayapandi Pandy, Srinivasa Reddy Bonam, Anji Reddy Raya, and Rama Rao Nadendla

20. Naringin and naringenin in neuroprotection and oxidative stressPauline Maciel August and Bernardo Gindri dos Santos

21. Nigella sativa L. and thymoquinone as neuroprotective antioxidantsAlireza Tavakkoli and Hossein Hosseinzadeh

22. Dietary antioxidants, epigenetics, and brain aging: A focus on resveratrolChristian Griñán-Ferré, Vanesa Izquierdo, and Mercè Pallàs

23. The role of saffron and its main components on oxidative stress in neurological diseases: A reviewMarjan Nassiri-Asl and Hossein Hosseinzadeh

24. Sulforaphane and its modulation of brain redox status: The mitochondria as a targetMarcos Roberto de Oliveira

25. Recommended resources for oxidative stress and dietary antioxidants in neurological diseasesRajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy

Index

Colin R Martin

Colin R. Martin RN, BSc, MSc, PhD, MBA, YCAP, FHEA, C.Psychol, AFBPsS, C.Sci is Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director of the Institute of Health and Wellbeing at the University of Suffolk, UK. He is a Chartered Health Psychologist and a Chartered Scientist. He also trained in analytical biochemistry, this aspect reflecting the psychobiological focus of much of his research within mental health. He has published or has in press well over 300 research papers and book chapters. He is a keen book author and editor having written and/or edited more than 50 books. These outputs include the prophetic insight into the treatment of neurological disease, Handbook of Behavior, Food and Nutrition (2011), Nanomedicine and the Nervous System (2012), Oxidative Stress and Dietary Antioxidants in Neurological Disease (2020), Zika Virus Impact, Diagnosis, Control and Models (2021), Factors Affecting Neurodevelopment: Genetics, Neurology, Behavior and Diet (2021), Diagnosis and Treatment of Spinal Cord Injury (2022), The Neurobiology, Physiology, and Psychology of Pain (2022) and The Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging (2023). Professor Martin is particularly interested in all aspects of the relationship between underlying physiological substrates and behavior, particularly in how these relationships manifest in both acute and chronic psychiatric disorder. He has published original research germane to significant mental health disorders including the areas of schizophrenia, anxiety, depression, self-esteem, alcohol and drug dependency, high secure forensic mental health and personality disorder. He has a keen interest in the impact of postviral illness and is actively involved in clinical research post-Covid pandemic and in particular, the impact of Long Covid on psychological, neurological, physiological and social functioning. He is involved in collaborative International research with many European and Non-European countries.

Affiliations and expertise

Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing, University of Suffolk, Ipswich, UK

Victor R Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

Affiliations and expertise

Professor, Department of Clinical Biochemistry, King’s College Hospital, London, UK; Emeritus Professor, Faculty of Life Sciences and Medicine, King’s College London, UK Visiting Professor, University of Hull, UK

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