Organic Chemistry in Action
The Design of Organic Synthesis
- 2nd Edition, Volume 51 - May 9, 1996
- Latest edition
- Authors: F. Serratosa, J. Xicart
- Language: English
The first edition of this book was welcomed with great enthusiasm by teachers and students. It therefore seemed opportune to publish a second, revised, updated and extended ed… Read more
The first edition of this book was welcomed with great enthusiasm by teachers and students. It therefore seemed opportune to publish a second, revised, updated and extended edition. Unfortunately, Professor Fèlix Serratosa died before he could complete this task. Some new material has been added, the more significant changes being:. The book has been restructured into two well-differentiated sections: Part A, dealing with conventional organic synthesis, and Part B, devoted exclusively to computer-assisted organic synthesis and based on the former Chapter 11 and Appendices 2, 3 and 4 of the first edition. As decided in advance, Part B was to be the sole responsibility of Dr. Josep Xicart, who prepared the first versions of the CHAOS (Computerisation and Heuristics Applied to Organic Synthesis) program under the direction of Professor Serratosa.
Part A. The Design of Organic SynthesisHeuristics and Organic SynthesisPure substancesReferencesAppendix A-1. Graph theoryMolecular Complexity IndicesReferencesThe Reactivity of Organic MoleculesReferencesMethodologiesSynthesis treeReferencesSynthetic Structural AnalysisSimplification. Heterolytic Disconnections: Heuristic PrinciplesReferencesSynthesis of Dissonant Systems. ReferencesMonocyclic and Polycyclic SystemsReferencesSystems with Unusual Structural Features: Quaternary Carbon Atoms, Medium-sized Rings and Bridged SystemsReferencesStereochemical Control in Monocyclic and Polycyclic SystemsReferencesAcyclic StereoselectionI. Stereocontrolled Aldol Condensations. ReferencesAcyclic StereoselectionII. Asymmetric Epoxidation and Dihydroxylation of Olefinic Double BondsReferencesChirality in Nature and Industry: The Present and the FutureEnzymes and Antibodies. ReferencesControl ElementsSummaryReferencesSelected Organic SynthesesReferences
Part B. Computer-Assisted Organic SynthesisComputers, Computation, Computerisation and Artificial Intelligence, the "Exploration Tree"References
Appendix: B-1. UGI's Theory of Chemical Constitution: EROS and IGORAppendix B-2. Instructions for the Use of the Chaos and Chaosbase ProgramsAppendix B-3. Chaos: Tables of Disconnection GroupsAppendix B-4 Suggested Exercises to be Solved by Chaos
- Edition: 2
- Latest edition
- Volume: 51
- Published: May 9, 1996
- Language: English
FS
F. Serratosa
Affiliations and expertise
Formerly at the University of Barcelona, Barcelona, Spain (Part A)JX
J. Xicart
Affiliations and expertise
University of Barcelona, Barcelona, Spain (Part B)Read Organic Chemistry in Action on ScienceDirect