Ord and Cd in Chemistry and Biochemistry

1st Edition - January 1, 1972
Author: Pierre Crabbe
Language: English
Hardback ISBN:
9 7 8 - 0 - 1 2 - 1 9 4 6 5 0 - 0
Paperback ISBN:
9 7 8 - 0 - 1 2 - 4 3 3 6 2 5 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 5 9 4 1 - 8

ORD and CD in Chemistry and Biochemistry: An Introduction essentially presents the necessary foreword and theoretical foundation for the useful application of optical rotatory… Read more

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ORD and CD in Chemistry and Biochemistry: An Introduction essentially presents the necessary foreword and theoretical foundation for the useful application of optical rotatory dispersion (ORD) and circular dichroism (CD) to certain common chemical problems. This book emphasizes the precision of ORD and CD data in terms of stereochemical information. The book begins with some historical references and a concise review of basic principles on stereochemistry. It further delves onto the phenomena of optical activity. Also included are the definitions and units commonly used in ORD and CD. The book also discusses optical properties of polymers, organometallic, and inorganic derivatives; and some of the aspects of magnetic optical rotator dispersion (MORD) and magnetic circular dichroism (MCD). A table that presents wavelength range of the Cotton effects of most chromophoric groupings concludes the book. This monograph is a helpful reference to students as well as professionals from both chemistry and biochemistry fields of science.

Preface

I. Basic Principles, Definitions, and Units

I-1. Historical Aspects

I-2. Structure, Configuration, Conformation

I-3. Optical Rotatory Dispersion—Cotton Effect

I-4. Circular Dichroism—Rotational Strength

I-5. Comparison between ORD and CD Curves

I-6. Theoretical Aspects

II. ORD and CD of Organic Functional Groups

II-1. Classification of Chromophores

II-2. Halogenoalkanes

II-3. Isolated Double Bonds

II-4. Dienes

II-5. Alienes

II-6. Alcohols

II-7. Saturated Ketones and Aldehydes

II-8. α-Cyclopropyl, α-Epoxyketones, Vicinal Effects

II-9. α,β-Unsaturated Ketones

II-10. β,γ-Unsaturated Ketones

II-11. Carboxylic Acids, Esters, Lactones, Lactams, Imides, Anhydrides

II-12. α-Hydroxy and α-Amino Acids

II-13. Oximes

II-14. Aromatic Chromophores

a) The Aromatic Quadrant Rule

b) The Aromatic Sector Rule

c) The Benzoate Sector Rule

d) The Dibenzoate Chirality Rule

e) The Modified Sector Rule

f) The Styrene Chirality Rule

II-15. Episulfides, Thiocarbonates and Thionocarbonates

II-16. Amines and Derivatives

II-17. Dithiocarbamates and Dithiourethanes

II-18. Azides

II-19. Azomethines, Nitrasoamines, N-Chloroamines, Nitro-, Nitryloxy-Derivatives, Aziridines, Pyrazolines

II-20. The Thiocyanate Chromophore

II-21. Other Sulfur Derivatives, Disulfides, Sulfoxides, Phosphorus Containing Chromophores, Etc.

II-22. Ethers, Ozonides, Nitrones, Nitroxides, Imines, C-Nitroso Compounds, Polyenes, etc.

III. Solvent and Temperature Effects

IV. Amides, Peptides, Nucleosides, Nucleotides, Pigments, and Porphyrins

IV-1. Amides, Small Peptides, Diketopiperazines

IV-2. Nucleosides, Nucleotides

IV-3. Pigments, Porphyrins, and Related Substances

V. Optically Active Polymers

V-1. Naturally Occurring Polymers

V-2. Synthetic High Polymers

VI. Metallic Complexes

VII. Magnetic Optical Rotatory Dispersion and Magnetic Circular Dichroism

Appendix

Problems

Tables

Table of Rules Presently Available in ORD-D

Table of Compounds, Functional Groups, and Chromophores

Author Index

Subject Index