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Elsevier

Oligomerization in Health and Disease

  • 1st Edition, Volume 117 - May 7, 2013
  • Latest edition
  • Editors: Jesus Giraldo, Francisco Ciruela
  • Language: English

This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and… Read more

Description

This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.

Key features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field

Readership

Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine

Table of contents

Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization

  1. Evolutionary, Physico-Chemical and Functional Mechanisms of Protein Homooligomerization

  • Structural, Evolutionary and Assembly Principles of Protein Oligomerization

    •

  • Physico-Chemical Principles of Protein Aggregation

    •

  • Structural Aspects of Amyloid Formation

    •

    Section II. Oligomerization in Seven-Transmembrane Receptors

  • Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers

    •

  • Challenges in the Development of Heteromer-GPCR-Based Drugs

    •

  • Oligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"

    •

  • G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders

    •

  • Disease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of Abuse

    •

    Section III. Oligomerization in Ion Channels

  • Social Networking among Voltage-Gated Potassium Channels

    •

  • Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy

    •

  • Consequences of Dimerization of the Voltage Gated Proton Channel

    •

  • Receptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate Receptors

    •

    Section IV. Oligomerization in Enzymes

  • The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase

    •

  • Oligomerization of Dynamin Superfamily Proteins in Health and Disease

    •

  • Multimerization of the Dnmt3a DNA Methyltransferase and its Functional Implications

    •

  • Oligomerization in Endoplasmic Reticulum Stress Signaling

    •

    Section V. Oligomerization in Regulatory Proteins

  • Toll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive Immunity

    •

  • Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease

    •

  • Chemokine Oligomerization in Cell Signaling and Migration

    •

  • Oligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking

    • Review quotes

    Praise for the series:
    "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." —British Medical Journal

    Product details

    • Edition: 1
    • Latest edition
    • Volume: 117
    • Published: May 30, 2013
    • Language: English

    About the editors

    JG

    Jesus Giraldo

    Dr.Jesús Giraldo currently teaches at Universitat Autònoma de Barcelona in Barcelona, Spain.
    Affiliations and expertise
    Universitat Autonoma de Barcelona, Spain

    FC

    Francisco Ciruela

    Dr. Francisco Ciruela currently teaches at University of Barcelona, Barcelona, Spain.
    Affiliations and expertise
    University of Barcelona, Spain

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