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Nucleic acid associated mechanisms in immunity and disease
- 1st Edition, Volume 161 - May 20, 2024
- Editors: Jayanta Chaudhuri, Uttiya Basu
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 8 8 9 4 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 8 8 9 5 - 4
Advances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of aut… Read more
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Request a sales quoteAdvances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding and respected serial on the subject matter
- Focuses on recent advances in immunology
Immunologists and infectious disease specialists, cell biologists and hematologists
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Chapter One: Mechanisms and functions of lncRNAs linked to autoimmune disease risk alleles
- Abstract
- 1 Introduction
- 2 Lnc13 in CeD and T1D
- 3 Carinh in IBD
- 4 IL21-AS1 in SLE
- 5 H19 in RA
- 6 Gas5 in MS
- 7 Discussion
- Acknowledgments
- References
- Chapter Two: Innate immune sensing of macromolecule homeostasis
- Abstract
- 1 Introduction
- 2 Innate immune sensing of protein homeostasis
- 3 Innate Immune Sensing of Host RNA Homeostasis
- 4 Innate Immune Sensing of DNA Homeostasis
- 5 Concluding Remarks and Prospectives
- References
- Chapter Three: The Sixth Sense: Self-nucleic acid sensing in the brain
- Abstract
- 1 Introduction
- 2 RIG-I and MDA5
- 3 PKR
- 4 TLR3
- 5 TLR 7/8
- 6 cGAS
- 7 AIM2 inflammasome
- 8 TLR9
- 9 Discussion
- Acknowledgments
- References
- Chapter Four: Post-transcriptional (re)programming of B lymphocyte development: From bench to bedside
- Abstract
- 1 Orchestration of hematopoiesis throughout ontogeny by gene expression programs
- 2 B-1a cells
- 3 LIN28B and B-1a cell development
- 4 Clinical relevance of LIN28B
- Acknowledgements
- References
- Chapter Five: Alternative DNA structures in hematopoiesis and adaptive immunity
- Abstract
- 1 Introduction
- 2 Alternative DNA structures and hematopoiesis
- 3 Alternative DNA structures and defects in early hematopoiesis
- 4 Alternative DNA structures and development of adaptive immune cells
- 5 Alternative DNA structures in adaptive immune responses
- 6 Concluding remarks
- Acknowledgments
- References
- Chapter Six: AID in non-Hodgkin B-cell lymphomas: The consequences of on- and off-target activity
- Abstract
- Abbreviations
- 1 Introduction to AID
- 2 Introduction to GC B cell-derived non-Hodgkin lymphomas
- 3 Consequences of AID activity in B-cell lymphoma
- 4 Expression of AID in lymphoma
- 5 Exposures affecting the lymphomagenic activities of AID
- 6 Therapeutic targeting of AID in lymphoma
- 7 Conclusions
- Acknowledgments
- References
- No. of pages: 198
- Language: English
- Edition: 1
- Volume: 161
- Published: May 20, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780443188947
- eBook ISBN: 9780443188954
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