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Nuclear Medicine in Clinical Diagnosis and Treatment

2-Volume Set

  • 3rd Edition - July 15, 2004
  • Latest edition
  • Authors: Peter J. Ell, Sam Gambhir
  • Language: English

This definitive and comprehensive 2 volume text-reference book is essential reading for those who are primarily involved in the practice of nuclear medicine. Over 180… Read more

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Description

This definitive and comprehensive 2 volume text-reference book is essential reading for those who are primarily involved in the practice of nuclear medicine. Over 180 contributors, all of them internationally recognized authorities, focus on current and newly available radionuclide techniques and directly apply them to clinical practice. Covering all of the major body systems and organs in which nuclear medicine procedures are used, the book takes a disease oriented approach and this new edition features the latest advances in diagnostic and therapeutic modalities used in the detection and treatment of cancer, heart disease, neurologic disorders, trauma and other common and less common diseases. There are major revisions/ new chapters in the areas of brain imaging, movement disorders, stroke, lymphoma therapy, bone density, non-neurologic drug discovery, molecular imaging, cost/benefit analysis.

Key features

  • Features over 4,400 high quality images depicting a full range of both common and rare diseases and abnormalities.
  • Emphasizes how to perform and interpret a test rather than the technical aspects of the procedure, and focuses on how to solve the diagnostic problems that occur in day-to-day practice.
  • Addresses practical considerations such as image interpretation, image optimization techniques, and pitfalls in image acquisition, and interpretation.
  • Offers state-of-the art global perspectives from an international team of editors and authors.

Readership

Nuclear Medicine specialists ( practitioners and trainees) There are 4,500 nuclear medicine specialists in the USA
Departments of Radiology ( I would not expect individual radiologists to buy this text)

Table of contents

Section 1: Nuclear medicine in tumor diagnosis and therapy

Part A: Diagnosis


1. Tumor-seeking radiopharmaceuticals: nature and mechanisms


2 Radionuclide imaging of hepatic tumors


3 PET in lymphoma and malignant melanoma


4 Parathyroid imaging


5 Adrenocortical scintigraphy


6 Gallium scintigraphy in tumor diagnosis and management


7 Thallium-201 chloride: a tumor imaging agent


8 MIBG in the diagnosis of neuroendocrine tumors


9 Peptide receptor scintigraphy in oncology


10 The diagnostic role of radiolabeled antibodies in cancer


11 Cancer cell biology basis for nuclear oncology


12 Differentiated thyroid carcinoma


13 Medullary thyroid cancer


14 Breast scintigraphy


15 Pediatric tumors


16 Functional analysis of cancer therapy effects in other organs


17 The use of intraoperative probes in surgical oncology


18 The sentinel lymph node in surgical oncology


19 FDG PET Imaging of Head and Neck Cancer


20 External Beam Radiotherapy Treatment Planning with PET


21 PET in aerodigestive tumors


22 PET in gynecological tumors (breast, cervical and ovarian)


23 Nuclear medicine imaging in pediatric oncology


24 Positron Emission Tomography (PET) in genitourinary tumors: prostate, bladder, testicular and renal cancer


25 Future clinical applications of PET (amino acid and nucleoside imaging)


26 PET imaging of brain tumors


Section 1: Nuclear medicine in tumor diagnosis and therapy

Part B: Radionuclide therapy


27 Principles of radionuclide therapy


28 Dosimetric and radiobiological considerations: The MIRD concept


29 Dosimetric and radiobiological considerations: Patient-individual dosimetry


30 Radioiodine therapy of the thyroid: Treatment of benign thyroid diseases


31 Radioiodine therapy of the thyroid: Treatment of thyroid malignancies


32 Phosphorus-32 therapy in myeloproliferative disorders


33 Palliation of bone pain


34 Radioimmunotherapy of hematologic neoplasms


35 Radioimmunotherapy of solid tumors


36 MIBG therapy


37 Receptor-targeted radiopeptide therapy


38 Use of radiolipiodol in the treatment of hepatic tumours


39 Alternative approaches to targeting therapy


40 New developments: Nuclear gene therapy


41 Atlas 1: PET and PET/CT


42 Atlas 2: SPET and SPET/CT


Section 2: Nuclear medicine in disorders of bones and joints


43 Bone scintigraphy: the procedure and interpretation


44 Evaluation of primary bone tumors


45 The evaluation of malignancy: metastatic bone disease


46 Assessment of infection


47 Radionuclide assessment of the painful joint prosthesis


48 Vascular manifestations


49 Bone scintigraphy in trauma


50 Bone scintigraphy in sports medicine


51 Growth and metabolic disorders


52 Arthritis: current status of scintigraphy and future trends


53 Radiation synovectomy


Section 3: Quantitative studies of gastrointestinal function


54 Salivary gland disorders


55 Esophageal function (transport and motility)


56 Gastric motility


57 Intestines: evaluation of absorption


58 Studies of small bowel and colonic transit


59 Hepatobiliary function: biliary kinetics


60 Scintigraphic measurement of hepatic function


Section 4: Nuclear medicine in acute care


61 Nuclear cardiology and cardiac transplantation


62 Cardiovascular conditions: venous thrombosis


63 Pulmonary embolism


64 Non-embolic disease of the lungs


65 Gastrointestinal bleeding


66 Cholescintigraphy


67 Neonatal hyperbilirubinemia


68 Nuclear medicine in acute care of neurological patients


69 Radiolabeled agents for the localization of infection and inflammation


70 Undiagnosed fever


71 Inflammatory bowel disease


72 Nuclear imaging in cardiovascular infection and cardiac transplant rejection


73 The immunocompromised patient


Section 5: Nuclear cardiology


74 Radiopharmaceuticals for the study of the heart


75 Radionuclide ventriculography and the assessment of impaired ventricular function


76 Infarct avid imaging and myocardial perfusion scintigraphy techniques using single photon radiotracers


77 Cardiac positron emission tomography


78 Cardiac stress


79 The detection of coronary artery disease


80 Assessment of prognosis in patients with known or suspected coronary artery disease


81 Assessment after myocardial revascularization


82 Assessment of myocardial viability in dysfunctional myocardium


83 Myocardial infarction: the assessment of thrombolysis


84 Congenital heart disease


85 Single-photon imaging of myocardial metabolism: the role of iodine 123 fatty acids and fluorine-18 deoxyglucose


86 Clinical applications of PET


87 Myocardial innervation: imaging and quantification


88 Nuclear medicine techniques in the assessment of human thrombosis and atheroma


Section 6: Nuclear medicine in neurological and psychiatric diagnosis


89 The blood-brain barrier


90 Lipophilic tracers: the amines


91 Lipophilic tracers for the study of regional cerebral blood flow


92 Ligands for neuroreceptor imaging by positron or single photon emission tomography


93 PET tracers for brain scanning


94 Neuroactivation


95 Image analysis in brain SPECT and PET


96 SPECT brain imaging in cerebrovascular disease


97 Nuclear medicine in the management of a patient with epilepsy


98 Nuclear medicine and the management of patients with Parkinson’s movement disorders


99 Anxiety disorders and affective disorders


100 Addictions


101 The management of patients with schizophrenia


102 PET and SPECT imaging in evaluating Alzheimer’s disease and related dementias


103 Nuclear medicine and drug studies in the brain


104 Cerebrospinal fluid physiology, clearance flow studies and cerebrospinal fluid shunt studies


105 Atlas 3: PET brain atlas


Section 7: Nuclear medicine in renal disorders


106 Overview of renal nuclear medicine


107 Radiopharmaceuticals: their intrarenal handling and localization


108 Dynamic static renal imaging


109 Quantitative evaluation of clearance


110 Measurement and interpretation of renal transit times


111 The role of PET in renal nuclear medicine


112 Renal infection


113 Pediatric aspects of radionuclides in nephrourology


114 Nuclear medicine in the clinical diagnosis and treatment of obstructive uropathy


115 Vascular disorders, with emphasis on hypertension


116 Renal failure


117 Space-occupying lesions and trauma


118 Renal transplant evaluation


119 The genital tract


Sction 8: Basic sciences


120 Fundamental molecular/cell biology


121 Radioisotope production


122 Radiochemistry


123 Radiopharmacy


124 Basic physics and detection of radiation


125 Nuclear medicine imaging instrumentation


126 Nuclear medicine computers: Basic principles


127 Nuclear medicine computers: Applications


128 Single photon emission computed tomography (SPECT)


129 Positron emission tomography (PET)


130 Primer on molecular imaging


131 Radiation protection and dosimetry in clinical practice


132 Clinical decision making: an introductory, quantitative approach to diagnostic investigations


133 ecision analysis fundamentals

Review quotes

"The new third edition of this textbook is unquestionably the ultimate reference book of this evolving specialty...I recommend 'Nuclear Medicine in Clinical Diagnosis & Treatment' as the definitive reference for the practice of clinical nuclear medicine." JAMA March 2005 p.1267

Product details

  • Edition: 3
  • Latest edition
  • Published: July 15, 2004
  • Language: English

About the authors

PE

Peter J. Ell

Affiliations and expertise
Professor of Nuclear Medicine, University College London, London, UK

SG

Sam Gambhir

Affiliations and expertise
Director, Molecular Imaging Program at Stanford; Professor of Radiology and Bio-X Program; Chief, Division of Nuclear Medicine, Stanford University School of Medicine, Stanford, CA, USA