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New Frontiers in Thoracic Pathology, An Issue of Surgical Pathology Clinics
- 1st Edition, Volume 17-2 - May 3, 2024
- Editor: Alain Charles Borczuk
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 0 8 5 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 0 8 6 - 1
In this issue of Surgical Pathology Clinics, guest editor Dr. Alain Borczuk brings his considerable expertise to the topic of New Frontiers in Thoracic Pathology. Top experts provi… Read more
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Request a sales quoteIn this issue of Surgical Pathology Clinics, guest editor Dr. Alain Borczuk brings his considerable expertise to the topic of New Frontiers in Thoracic Pathology. Top experts provide new insights into emerging technology that will affect thoracic pathology in both neoplastic and non-neoplastic disease. This issue covers updates in the utilization of molecular testing in surgical pathology of lung cancer and mesothelioma, highlights uncommon tumors in the differential of common tumors, and shares new approaches to non-neoplastic disease, including new clinicopathologic entities.
- Contains 13 relevant, practice-oriented topics including silicosis and non-asbestos associated pneumoconiosis; pathology of COVID-19 lung disease; salivary gland type lung cancer; microsatellite instability, mismatch repair and tumor mutation burden in lung cancer; artificial intelligence in lung pathology; and more.
- Provides in-depth clinical reviews on new frontiers in thoracic pathology, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Pathologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Preface
- Smoking-Related Interstitial Lung Disease: Historical Perspective and Advances in the Twenty-first Century
- Overview
- Pulmonary Langerhans cell histiocytosis
- Respiratory bronchiolitis-interstitial lung disease
- Desquamative interstitial pneumonia
- Smoking-related interstitial fibrosis
- Combined pulmonary fibrosis and emphysema
- Summary
- Clinics care points
- Sources of support and funding
- Conflict of interest declaration:
- Granulomatous Lung Diseases: A Practical Approach and Review of Common Entities
- Overview
- Infectious causes of granulomatous lung disease
- Noninfectious causes of granulomatous lung disease
- Summary
- Clinics care points
- Update on Silicosis
- Overview
- Current populations at risk
- Clinical and radiologic classification of silicosis
- Pathologic features of silicosis
- Pathologic differential diagnosis
- Silica exposure and tuberculosis
- Silica exposure and lung cancer
- Silica exposure and connective tissue disease
- Silica and vasculitis
- Functional effects, treatment, and prognosis
- Pathology of COVID-19 Lung Disease
- Overview
- Clinical features of COVID-19 disease
- Pathology of acute COVID-19 pneumonia
- Pathogenesis
- Long COVID-19
- Summary
- Clinics care points
- Interstitial Lung Abnormalities
- Overview
- Background
- Definition of interstitial lung abnormalities
- Risk factors for interstitial lung abnormalities
- Significance of interstitial lung abnormalities and progression to interstitial lung disease
- Impact of coronavirus disease 2019 pandemic
- Interstitial lung abnormalities and lung cancer
- Histologic correlates
- What does this mean for the pathologist?
- Background lung findings correlating with interstitial lung abnormalities
- Knowledge gaps/future directions
- Summary
- Clinics care points
- Evolving Diagnostic Approach of Pulmonary Salivary Gland-type Tumors
- Background: need for review
- Classification of pulmonary salivary gland-type tumors
- Diagnostic challenges with limited biopsy samples
- Unique clinicopathological features of individual pulmonary salivary gland-type tumors
- Pattern based approach to diagnose salivary gland-type tumors on lung biopsy
- Summary
- Clinics care points
- Funding sources
- Sarcoma of the Lung and Mediastinum
- Introduction
- Synovial sarcoma
- Liposarcoma
- Intimal sarcoma
- Inflammatory myofibroblastic tumor
- Epithelioid hemangioendothelioma
- Primary pulmonary myxoid sarcoma
- Other sarcomas
- Clinics care points
- Nonmesothelial Spindle Cell Tumors of Pleura and Pericardium
- Overview
- Gross features, including radiological features
- Microscopic features
- Primary pleural tumors
- Desmoid fibromatosis
- Metastases
- Summary
- Clinics care points
- Invasion and Grading of Pulmonary Non-Mucinous Adenocarcinoma
- Overview
- Invasion and pathologic stage
- Gross and microscopic measurements of invasion
- Microscopic measurement of invasion
- Differential diagnosis: mimickers of invasion
- Summary (invasion)
- Tumor grading: background
- A new grading system
- The proposed grading system
- Tumor grade: pitfalls
- Prospective applications of grading
- Summary
- Clinics care points
- Pathologic Response Evaluation in Neoadjuvant-Treated Lung Cancer
- Introduction
- Gross features
- Microscopic features
- Differential diagnosis
- Practical applications
- Summary
- Clinics care points
- Microsatellite Instability, Mismatch Repair, and Tumor Mutation Burden in Lung Cancer
- Background
- Microsatellite instability/mismatch repair deficiency
- Microsatellite instability/mismatch repair testing methodology
- Tumor mutation burden
- Tumor mutation burden testing methodology
- Tumor mutation burden and human leukocyte antigen
- Current National Comprehensive Cancer Network guidelines insight
- Mutations in non-small cell lung cancer and immune checkpoint inhibitors
- Microsatellite instability/mismatch repair deficiency, tumor mutation burden, and programmed death ligand 1 relationship
- Summary and future avenues
- Molecular Testing in Lung Cancer: Recommendations and Update
- Overview
- Tissue stewardship
- Use of molecular tests in the diagnosis of lung cancer
- Use of molecular tests in staging
- Use of molecular tests in therapeutic prediction
- Summary
- Clinics care points
- Applications of Artificial Intelligence in Lung Pathology
- Introduction
- Definitions
- Applications
- Regulatory
- Reimbursement
- Deployment
- Discussion
- Clinics care points
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 17-2
- Published: May 3, 2024
- Imprint: Elsevier
- Hardback ISBN: 9780443130854
- eBook ISBN: 9780443130861
AB
Alain Charles Borczuk
Affiliations and expertise
Professor of Pathology and Vice chairperson for Anatomic, Pathology, Northwell Health