Neuroreceptors
Physiology, Pathology, and Therapeutic Targeting
- 1st Edition - February 1, 2027
- Latest edition
- Editors: Deepa S. Mandlik, Mithun Singh Rajput
- Language: English
Neuroreceptors: Physiology, Pathology, and Therapeutic Targeting offers an in-depth exploration of the cellular and molecular mechanisms underlying brain receptor function and th… Read more
Description
Description
Neuroreceptors: Physiology, Pathology, and Therapeutic Targeting offers an in-depth exploration of the cellular and molecular mechanisms underlying brain receptor function and their critical roles in health and disease. This authoritative reference addresses ionotropic, metabotropic, receptor tyrosine kinases, and nuclear receptors, detailing their structures, signaling pathways, and physiological functions. The book emphasizes how receptor malfunctions contribute to neurological and psychiatric conditions such as Parkinson’s disease, Alzheimer’s, schizophrenia, and epilepsy, bridging fundamental biology with clinical relevance. Through comprehensive coverage of experimental methodologies—including imaging, electrophysiology, and molecular pharmacology—it equips researchers and clinicians with practical insights for investigating receptor dynamics and developing targeted therapies. The final sections focus on innovative therapeutic strategies, including gene editing, receptor modulation, and personalized medicine approaches, reflecting current advances in translational neuroscience. This resource is designed to serve as a vital tool for scientists, healthcare professionals, and students seeking a cohesive understanding of receptor biology and its therapeutic potential, fostering progress in neuropharmacology and neurotherapeutics
Key features
Key features
- Examines detailed mechanisms of brain receptors and their roles in neurological disorders
- Integrates molecular, cellular, and clinical perspectives for comprehensive understanding
- Presents current experimental techniques and translational therapeutic strategies
- Highlights receptor dysfunction in neurodegenerative and psychiatric diseases
- Provides a unified resource supporting research, education, and clinical practice
Readership
Readership
Neuroscience researchers and clinicians
Table of contents
Table of contents
Part I – Foundations
1. Introduction to Neuroreceptors: Structure, Function, and Diversity
2. Techniques in Receptor Biology: From Molecular to Systems Neuroscience
3. Neurotransmission and Receptor Dynamics in Health
Part II – Receptor Families in the Nervous System
4. Ionotropic Receptors: Gatekeepers of Fast Synaptic Transmission
5. Metabotropic Receptors: G-Protein Coupling and Intracellular Cascades
6. Receptor Tyrosine Kinases and Neurotrophic Signaling
7. Nuclear Receptors in the Brain: Modulators of Gene Expression and Neuroprotection
Part III – Receptor Dysfunction in Disease
8. Excitotoxicity, Cholinergic Dysfunction, and Neurodegeneration
9. Dopamine and Serotonin Receptors in Psychiatric and Movement Disorders
10. Autoimmunity and Channelopathies: Receptor Targets in Neuromuscular and Central Nervous System Diseases
11. Receptor Mechanisms in Pain, Migraine, and Sensory Disorders
Part IV – Translational Medicine
12. Pharmacological Modulation of Neuroreceptors: Current Therapies and Limitations
13. Emerging Therapies: Gene Editing, Biologics, and Receptor-Targeted Nanomedicine
14. Future Directions: Personalized Medicine and Neuroreceptor-Based Therapeutics
1. Introduction to Neuroreceptors: Structure, Function, and Diversity
2. Techniques in Receptor Biology: From Molecular to Systems Neuroscience
3. Neurotransmission and Receptor Dynamics in Health
Part II – Receptor Families in the Nervous System
4. Ionotropic Receptors: Gatekeepers of Fast Synaptic Transmission
5. Metabotropic Receptors: G-Protein Coupling and Intracellular Cascades
6. Receptor Tyrosine Kinases and Neurotrophic Signaling
7. Nuclear Receptors in the Brain: Modulators of Gene Expression and Neuroprotection
Part III – Receptor Dysfunction in Disease
8. Excitotoxicity, Cholinergic Dysfunction, and Neurodegeneration
9. Dopamine and Serotonin Receptors in Psychiatric and Movement Disorders
10. Autoimmunity and Channelopathies: Receptor Targets in Neuromuscular and Central Nervous System Diseases
11. Receptor Mechanisms in Pain, Migraine, and Sensory Disorders
Part IV – Translational Medicine
12. Pharmacological Modulation of Neuroreceptors: Current Therapies and Limitations
13. Emerging Therapies: Gene Editing, Biologics, and Receptor-Targeted Nanomedicine
14. Future Directions: Personalized Medicine and Neuroreceptor-Based Therapeutics
Product details
Product details
- Edition: 1
- Latest edition
- Published: February 1, 2027
- Language: English
About the editors
About the editors
DM
Deepa S. Mandlik
Dr. Deepa S. Mandlik is an Associate Professor of Pharmacology with more than 18 years of experience in teaching, research, and academic administration. She is currently serving in the Department of Pharmacology at the Bharati Vidyapeeth (Deemed to be University) Poona College of Pharmacy, Pune, Maharashtra, India. Dr. Mandlik completed her Bachelor of Pharmacy (B. Pharm.) from the University of Pune, where she secured First Rank in the university. She subsequently obtained her Master of Pharmacy (M. Pharm.) in Pharmacology from the University of Pune and earned her Ph.D. in Pharmaceutical Sciences. An accomplished academician and researcher, Dr. Mandlik has published more than 88 research papers in reputed national and international peer-reviewed journals. Her research has received widespread recognition, with an h-index of 20 and more than 1,850 citations. She has authored more than seven pharmaceutical books and contributed over twenty book chapters published by internationally renowned publishers.
Dr. Mandlik is a recognized postgraduate and Ph.D. research supervisor. She has successfully guided several postgraduate and doctoral research scholars and has received research grants from various funding agencies in support of her scientific work. Her research interests encompass preclinical evaluation of herbal medicines, inflammation and immunology, cancer, diabetes, osteoporosis, rheumatoid arthritis and inflammatory bowel disease. Her work focuses on the development and pharmacological evaluation of novel therapeutic strategies and the translation of scientific discoveries into clinically relevant healthcare solutions. In addition to her research contributions, Dr. Mandlik has actively participated in curriculum development, academic administration, and professional training, contributing significantly to pharmaceutical education and research in India.
Affiliations and expertise
Bharati Vidyapeeth, Poona College of Pharmacy, IndiaMR
Mithun Singh Rajput
Dr. Mithun Singh Rajput works with the Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India as Assistant Professor. He has expertise in neuropharmacology and received his doctoral degree from the Faculty of Medicine, M.G.M. Medical College, Indore, India. He is a recipient of two years’ National Postdoctoral Fellowship from SERB, Department of Science and Technology, India and is associated with the research project as principal investigator. He has overall teaching and research experience of twelve years. His areas of interest include the diagnosis and mitigation strategies for various neurodegenerative disorders like Alzheimer’s disease and cerebral ischemia, diabetes associated cognitive impairment, etc. He has received five research grants from government agencies and universities. Dr. Rajput has two patents, published three book chapters and has edited four books. Dr. Rajput is credited with thirty-two publications in peer reviewed indexed journals. He has served many government funding agencies, and journals as a reviewer and editorial board member.
Affiliations and expertise
Assistant Professor, Department of Pharmacology, Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India