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Neuroparasitology and Tropical Neurology
- 1st Edition, Volume 114 - July 3, 2013
- Editors: Hector H. Garcia, Herbert B. Tanowitz, Oscar H. Del Brutto
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 4 - 5 3 4 9 0 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 4 - 5 3 4 9 9 - 6
Neuroparasitology and Tropical Neurology, a new volume in The Handbook of Clinical Neurology, provides a comprehensive and contemporary reference on parasitic infections of the hu… Read more
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Request a sales quoteNeuroparasitology and Tropical Neurology, a new volume in The Handbook of Clinical Neurology, provides a comprehensive and contemporary reference on parasitic infections of the human nervous system. Parasitic infections are varied and some are resolved by the host’s immune system, other infections may become established even though unnoticed, and some cause severe disease and death. In our modern world, neuroparasitoses are no longer geographically isolated and these infections now appear worldwide. Outside of a very few well understood pathologies, most parasitic infections have been neglected in the neurological literature and most neurologists have never diagnosed such an infection. This volume details how, with the advent of modern neuroimaging techniques, improved diagnostic applications of molecular biology, more accurate immunodiagnosis, and minimally invasive neurosurgery, human nervous system parasitoses are now diagnosed and treated, with increasing frequency. The book is divided into six sections, and begins with an introduction to the mechanisms of infection, diagnosis, and pathology of parasitic diseases. Subsequent chapters detail protozoan diseases and a section covering each of the major classes of human-infecting helminths: nematodes (roundworms), trematodes (flukes), and cestodes (tapeworms). The final section contains chapters on other important areas of tropical clinical medicine including the neurological complications of venomous bites and tropical nutritional deficiencies. Neuroparasitology and Tropical Neurology will be of interest to neurologists, neurosurgeons and other health professionals encountering patients with parasitic infections.
- A comprehensive reference resource on the diagnosis and treatment of parasitic infections of the human nervous system
- Focuses on the impact of modern neuroimaging techniques, improved diagnostic applications of molecular biology, more accurate immunodiagnosis, and minimally invasive neurosurgery to diagnose parasitoses
- International list of contributors including the leading workers in the field
Clinical and research neurologists, neurosurgeons, and medical professionals involved in the diagnosis and treatment of parasitic infections
Handbook of Clinical Neurology 3rd Series
Foreword
Preface
Contributors
Section 1: Introduction
Chapter 1. Neurological aspects of neglected tropical diseases: an unrecognized burden
Introduction
Tropical diseases with neurological implications: an attempt at classification
The unrecognized burden of tropical neurology
The challenge of assessing the burden of tropical neurological diseases
Epilepsy: the silent epidemic
The challenge of ensuring that all those in need are reached by the national health services
A public health strategy to reduce the burden of tropical neurological diseases
References
Section 2: Pathophysiology and characteristics of parasitic infections
Chapter 2. Mechanisms of CNS invasion and damage by parasites
Introduction
Mechanisms of CNS invasion by parasites
Mechanisms of CNS structural and/or functional damage by parasites
Concluding remarks and future directions
Acknowledgments
References
Chapter 3. Immunodiagnosis of CNS parasitic infections
Introduction
Diseases that are localized primarily in the CNS
Other parasitic diseases of the CNS
Conclusions
Acknowledgment
References
Chapter 4. Imaging of parasitic infections of the central nervous system
Protozoa
Nematodes
Trematodes
Cestodes
Conclusion
References
Chapter 5. Pathology of CNS parasitic infections
Introduction
Protozoal Infections
Metazoal infections
References
Section 3: Protozoa
Chapter 6. Cerebral malaria
Introduction
Pathophysiology
Clinical manifestations
Pediatric patients
Adult patients
Treatment
Neurological sequelae
Epidemiology
Malaria in travelers
Prevention strategies and future directions
Conclusion
References
Chapter 7. American trypanosomiasis
Introduction and epidemiology
Transmission and natural cycle of t. Cruzi
Clinical symptoms and stages of the infection
Acute reactivation of chagas disease
Cerebrovascular complications of chagas disease
Diagnosis of American trypanosomiasis
Treatment
Concluding remarks
References
Chapter 8. Toxoplasmosis
Toxoplasma gondii: brief history and overview
The parasite and its life cycle
Transmission
Epidemiology
Immune response
Toxoplasmosis: clinical aspects
Summary
References
Chapter 9. Entamoeba histolytica brain abscess
Introduction
Microbiology
Pathogenesis
Epidemiology
Clinical presentations of amebiasis
Therapy
References
Chapter 10. Infections with free-living amebae
Introduction
Historical perspective
Taxonomy and classification
Acanthamoeba
Balamuthia mandrillaris
Naegleria fowleri
Sappinia pedata
Conclusions
References
Further-reading
Chapter 11. Human African trypanosomiasis
Introduction, transmission, and epidemiology
Pathogenesis and neuropathology
Clinical features
Diagnosis
Treatment
Control and prevention
Future developments
References
Chapter 12. Microsporidiasis
Introduction
Life cycle and pathogenesis
Clinical manifestations
Diagnosis
Treatment
Prevention
References
Chapter 13. Neurological manifestations of human leishmaniasis
Introduction to neurological manifestations of leishmaniasis
Peripheral demyelinating immune-mediated neuropathy in visceral leishmaniasis
Peripheral neuropathy in cutaneous leishmaniasis patients by direct or close parasite involvement
Central nervous system involvement in visceral leishmaniasis
Neuropathy induced by leishmanicidal treatments
Conclusion
References
Chapter 14. Neurological manifestations of human babesiosis
Introduction
Evidence in an animal model of neurological manifestations associated with Babesia infection
Human neurological manifestations associated with Babesia infection
Diagnosis
Treatment and prevention
Conclusions
Acknowledgment
References
Section 4: Nematoda
Chapter 15. Eosinophilic meningitis
Introduction
Angiostrongylus cantonensis
Gnathostoma spinigerum
Taenia solium
References
Chapter 16. Toxocariasis
Introduction
Historical background
Life cycle
Epidemiology
Clinical features
Diagnosis
Treatment
References
Chapter 17. Strongyloides stercoralis infection complicating the central nervous system
Introduction
Immune response
Risk factors
Clinical manifestations
Strongyloidiasis stercoralis and gram-negative meningitis
Diagnosis
Treatment
References
Chapter 18. Neurological manifestations of filarial infections
Introduction
Dracunculiasis
Onchocerciasis
Loa loa
Lymphatic filariasis
Mansonella perstans
Conclusions
References
Chapter 19. Neurotrichinellosis
Introduction
Epidemiology
Factors affecting the severity of the disease
Pathogenesis of neurotrichinellosis
Neurological complications
Differential diagnosis of neurotrichinellosis
Laboratory diagnosis
Treatment
Practical recommendations
References
Chapter 20. Baylisascaris larva migrans
Introduction
Epidemiology and life cycle
Clinical disease
Pathogenesis
Ocular disease
Diagnosis
Treatment
Prevention
Other baylisascaris species
References
Chapter 21. Other helminthic infections: Ascariasis, Dracontiasis, Lagochilascariasis, Micronemiasis
Introduction
Ascariasis
Dracontiasis
Human lagochilascariasis
Micronemiasis
References
Section 5: Trematoda
Chapter 22. Schistosomiasis of the nervous system
Introduction
Life cycle
Clinical schistosomiasis
Neuroschistosomiasis
Treatment for neuroschistosomiasis
Concluding remarks
References
Chapter 23. Paragonimiasis
Introduction
Morphology and taxonomy
Species infecting humans
Life cycle
Epidemiology
Pathogenesis and pathology
Clinical manifestations
Diagnosis
Treatment
References
Chapter 24. Direct and indirect affection of the central nervous system by Fasciola infection
Introduction
Human fascioliasis
Acute phase
Chronic phase
Fascioliasis affecting the central nervous system
Intracranial invasion by migrating flukes
Neurological impact of liver fascioliasis
Neurological symptoms described
Accompanying ophthalmological disorders
Paraclinical examinations
Ectopic localization of a migratory worm
Immuno-allergic and toxic effects on the central nervous system caused by flukes in the liver
Diagnosis of neurological fascioliasis
Coprological analyses
Serological tests
Treatment of neurological fascioliasis
Conclusion
Acknowledgments
References
Section 6: Cestoda
Chapter 25. Neurocysticercosis
Introduction
Epidemiology
Life cycle of taenia solium
Etiopathogenesis
Types of NCC
Clinical manifestations
Diagnosis
Treatment
Control measures
References
Chapter 26. Cystic and alveolar echinococcosis
Introduction
Biological and epidemiological background
Diagnosis and clinical management
Conclusions and outlook
References
Chapter 27. Other cestodes: sparganosis, coenurosis and Taenia crassiceps cysticercosis
Introduction
Sparganosis
Coenurosis
Taenia crassiceps cysticercosis
References
Section 7: Other tropical neurological disorders
Chapter 28. Neurological effects of venomous bites and stings: snakes, spiders, and scorpions
Snake bites
Spider bites
Scorpion stings
References
Chapter 29. Effects of geohelminth infections on neurological development
Introduction
The geohelminths themselves
Distribution in a population and across time
Pathways
Models of child development
The evidence
Summary of issues
Conclusions
References
Chapter 30. Nutritional disorders in tropical neurology
Introduction
Malnutrition
Specific deficiencies of micronutrients and vitamins
Neurological disorders associated with specific vitamins
Nutritional neuropathies and myeloneuropathies
References
Index
- No. of pages: 432
- Language: English
- Edition: 1
- Volume: 114
- Published: July 3, 2013
- Imprint: Elsevier
- Hardback ISBN: 9780444534903
- eBook ISBN: 9780444534996
HG
Hector H. Garcia
Affiliations and expertise
Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, PeruHT
Herbert B. Tanowitz
Affiliations and expertise
Albert Einstein College of Medicine, Bronx, NY, USAOD
Oscar H. Del Brutto
Affiliations and expertise
Hospital-Clinica Kennedy, Guayaquil, EcuadorRead Neuroparasitology and Tropical Neurology on ScienceDirect