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Netter's Atlas of Human Embryology
- 2nd Edition - September 22, 2023
- Authors: Larry R. Cochard, Angelique N. Dueñas
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 6 1 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 7 9 3 - 0
Illustrated by the world-renowned Frank H. Netter, MD and artists working in his tradition, Netter's Atlas of Human Embryology, 2nd Edition, provides a rich pictorial overvi… Read more
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Request a sales quoteIllustrated by the world-renowned Frank H. Netter, MD and artists working in his tradition, Netter's Atlas of Human Embryology, 2nd Edition, provides a rich pictorial overview of human prenatal development. For each stage of development and for each body system, you'll find a brief description of the developmental plan, with key concepts and terminology, followed by discussions of histological principles, the classification of congenital anomalies, and basic cellular, molecular, and genetic concepts. An emphasis on morphological patterns in the embryo and fetus makes it easy to understand the structure and function of the adult body and the embryonic basis of natural variation as well as birth anomalies.
- Uses vibrant, high-quality illustrations and concise text to teach key points quickly, effectively, and memorably.
- Includes new Inclusionary Consideration Points that detail key information such as differences between sex and gender—particularly for the embryology of sex determination; and perspectives on disability and disability advocacy—including person-first vs. identity-first language; plus new illustrations with more diversity and better representation of skin tones, sex, and body habitus.
- Discusses topics new to this edition, including Conjoined Twins, Early Detection of Pregnancy, Exstrophy of the Bladder, Genetic Sex Variations, Congenital Limb Anomalies, Holoprosencephaly, and more.
- Provides expanded coverage of clinical correlations and congenital anomalies and new Clinical Notes boxes throughout.
- Contains summary tables and terminology sections at the end of each chapter, plus an appendix with all major congenital anomalies and their embryonic basis, making it easy to review course material and prepare for the USMLE.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, make notes and highlights, and have content read aloud.
Evolve Instructor site with an image collection is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.
Medical students, anatomy/embryology students in health profession or undergrad courses.
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Preface
- About the Authors
- Acknowledgments
- About the Artists
- 1. Overview of Developmental Events, Processes, and Anomalies
- 1.1. Timeline
- 1.2. THE FIRST AND SECOND WEEKS
- 1.3. THE EARLY EMBRYONIC PERIOD
- 1.4. THE LATE EMBRYONIC PERIOD
- 1.5. THE FETAL PERIOD
- 1.6. SAMPLES OF EPITHELIA AND CONNECTIVE TISSUE
- 1.7. SKIN AND EMBRYONIC CONNECTIVE TISSUE
- 1.8. INDUCTION
- 1.9. APOPTOSIS
- 1.10. GENETIC DETERMINATION OF EMBRYONIC AXES AND SEGMENTS
- 1.11. SEGMENTATION AND SEGMENT FATES
- 1.12. CELL ADHESION AND CELL MIGRATION
- 1.13. CELL DIFFERENTIATION AND CELL FATES
- 1.14. GROWTH FACTORS
- 1.15. CLASSIFICATION OF NONNORMAL PROCESSES
- 1.16. CLASSIFICATION OF MULTIPLE ANOMALIES: SYNDROME VERSUS A SEQUENCE
- 1.17. NORMAL VERSUS MAJOR VERSUS MINOR MALFORMATIONS
- 1.18. MARFAN SYNDROME
- 1.19. APERT AND CORNELIA DE LANGE SYNDROMES
- 1.20. EXAMPLES OF DEFORMATIONS
- 1.21. EXAMPLE OF A DEFORMATION SEQUENCE
- 1.22. DRUG-INDUCED EMBRYOPATHIES
- 2. Early Embryonic Development and the Placenta
- 2.1. Timeline
- 2.2. Adult Uterus, Ovaries, and Uterine Tubes
- 2.3. Ovary, Ova, and Follicle Development
- 2.4. The Menstrual Cycle and Pregnancy
- 2.5. Ovulation, Fertilization, and Migration down the Uterine Tube
- 2.6. Ectopic Pregnancy
- 2.7. Tubal Pregnancy
- 2.8. Interstitial, Abdominal, and Ovarian Pregnancy
- 2.9. Implantation and Extraembryonic Membrane Formation
- 2.10. Gastrulation
- 2.11. Neurulation and Early Placenta and Coelom Development
- 2.12. Folding of the Gastrula
- 2.13. The Vertebrate Body Plan
- 2.14. Formation of the Placenta
- 2.15. The Endometrium and Fetal Membranes
- 2.16. Placental Structure
- 2.17. External Placental Structure; Placental Membrane
- 2.18. Placental Variations
- 2.19. Placenta Previa
- 2.20. Early Detection of Pregnancy
- 2.21. Twinning
- 2.22. Summary of Ectodermal Derivatives
- 2.23. Summary of Endodermal Derivatives
- 2.24. Summary of Mesodermal Derivatives
- 3. The Nervous System
- 3.1. Timeline
- 3.2. Formation of the Neural Plate
- 3.3. Neurulation
- 3.4. Neural Tube and Neural Crest
- 3.5. Defects of the Spinal Cord and Vertebral Column
- 3.6. Defects of the Brain and Skull
- 3.7. Neuron Development
- 3.8. Development of the Cellular Sheath of Axons
- 3.9. Development of the Spinal Cord Layers
- 3.10. Alar and Basal Plates
- 3.11. Development of the Peripheral Nervous System
- 3.12. Somatic Versus Splanchnic Nerves
- 3.13. Growth of the Spinal Cord and Vertebral Column
- 3.14. Embryonic Dermatomes
- 3.15. Adult Dermatomes
- 3.16. Early Brain Development
- 3.17. Further Development of Forebrain, Midbrain, and Hindbrain
- 3.18. Development of Major Brain Structures
- 3.19. Growth of the Cerebral Hemispheres
- 3.20. Derivatives of the Forebrain, Midbrain, and Hindbrain
- 3.21. Forebrain wall and Ventricles
- 3.22. Relationship Between Telencephalon and Diencephalon
- 3.23. Cross Sections of the Midbrain and Hindbrain
- 3.24. Production of Cerebrospinal Fluid
- 3.25. Development of the Ventricles
- 3.26. Congenital Ventricular Defects
- 3.27. Development of Motor Nuclei in the Brain Stem
- 3.28. Segmentation of the Hindbrain
- 3.29. Development of the Pituitary Gland
- 4. The Cardiovascular System
- 4.1. Timeline
- 4.2. Early Vascular Systems
- 4.3. Early Development of the Cardinal SYSTEM OF VEINS
- 4.4. Transformation to the Postnatal Pattern
- 4.5. Vein Anomalies
- 4.6. Aortic Arch Arteries
- 4.7. Aortic Arch Anomalies
- 4.8. Anomalous Origins of the Pulmonary Arteries
- 4.9. Intersegmental Arteries and Coarctation of the Aorta
- 4.10. Summary of Embryonic Blood Vessel Derivatives
- 4.11. Formation of Blood Vessels
- 4.12. Formation of the Left and Right Heart Tubes
- 4.13. Formation of a Single Heart Tube
- 4.14. Chambers of the Heart Tube
- 4.15. OVERVIEW NEAR THE END OF THE FOURTH WEEK
- 4.16. Partitioning of the Heart Tube
- 4.17. Atrial Separation
- 4.18. Spiral (Aorticopulmonary) Septum
- 4.19. Completion of the Spiral (Aorticopulmonary) Septum
- 4.20. Ventricular Separation and Bulbus Cordis
- 4.21. Adult Derivatives of the Heart Tube Chambers
- 4.22. Fetal Circulation
- 4.23. Transition to Postnatal Circulation
- 4.24. Congenital Heart Defect Concepts
- 4.25. Ventricular Septal Defects
- 4.26. Atrial Septal Defects
- 4.27. Spiral Septum Defects
- 4.28. Patent Ductus Arteriosus
- 5. The Respiratory System
- 5.1. Timeline
- 5.2. Early Primordia
- 5.3. Formation of the Pleural Cavities
- 5.4. The relationship Between Lungs and Pleural Cavities
- 5.5. Visceral and Parietal Pleura
- 5.6. Development of the Diaphragm
- 5.7. Congenital Diaphragmatic Hernia
- 5.8. The Airway at 4 TO 7 Weeks
- 5.9. The Airway at 7 TO 10 Weeks
- 5.10. Development of Bronchioles and Alveoli
- 5.11. Bronchial Epithelium Maturation
- 5.12. Congenital Anomalies of the Lower Airway
- 5.13. Airway Branching Anomalies
- 5.14. Bronchopulmonary Sequestration
- 5.15. Palate Formation in the Upper Airway
- 6. The Gastrointestinal System and Abdominal Wall
- 6.1. Timeline
- 6.2. Early Primordia
- 6.3. Formation of the gut Tube and Mesenteries
- 6.4. Foregut, Midgut, and Hindgut
- 6.5. Abdominal Veins
- 6.6. Foregut and Midgut Rotations
- 6.7. Meckel’s Diverticulum
- 6.8. Lesser Peritoneal Sac
- 6.9. Introduction to the Retroperitoneal Concept
- 6.10. Midgut Loop
- 6.11. Abdominal Ligaments
- 6.12. Abdominal Foregut Organ Development
- 6.13. Development of Pancreatic Acini and Islets
- 6.14. Congenital Pancreatic Anomalies
- 6.15. Development of the Hindgut
- 6.16. Duplication, Atresia, and Situs Inversus
- 6.17. Megacolon (Hirschsprung’s Disease)
- 6.18. Summary of gut Organization
- 6.19. Development of the Abdominal Wall
- 6.20. Abdominal Hernias
- 6.21. Testes’ Descent Through the Deep Body Wall
- 6.22. Coverings of the Spermatic Cord
- 6.23. The Adult Inguinal Region
- 6.24. Anomalies of the Processus Vaginalis
- 7. The Urogenital System
- 7.1. Timeline
- 7.2. Early Primordia
- 7.3. Division of the Cloaca
- 7.4. Exstrophy of the Bladder and Cloaca
- 7.5. Congenital Cloacal Anomalies
- 7.6. Pronephros, Mesonephros, and Metanephros
- 7.7. Development of the Metanephros
- 7.8. Ascent and Rotation of the Metanephric Kidneys
- 7.9. Kidney Rotation Anomalies and Renal Fusion
- 7.10. Kidney Migration Anomalies and Blood Vessel Formation
- 7.11. Hypoplasia
- 7.12. Ureteric bud Duplication
- 7.13. Ectopic Ureters
- 7.14. Bladder Anomalies
- 7.15. Allantois/Urachus Anomalies
- 7.16. Primordia of the Genital System
- 7.17. 8-Week Undifferentiated (Indifferent) Stage
- 7.18. Anterior View of the Derivatives
- 7.19. Paramesonephric Duct Anomalies
- 7.20. Homologues of the External Genital Organs
- 7.21. Hypospadias and Epispadias
- 7.22. Gonadal Differentiation
- 7.23. Testis, Epididymis, and Ductus Deferens
- 7.24. Descent of Ovaries
- 7.25. Ova and Follicles
- 7.26. Summary of Urogenital Primordia and Derivatives
- 7.27. Summary of Genital Primordia and Derivatives
- 8. The Musculoskeletal System
- 8.1. Timeline
- 8.2. Myotomes, Dermatomes, and Sclerotomes
- 8.3. Muscle and Vertebral Column Segmentation
- 8.4. Mesenchymal Primordia at 5 and 6 Weeks
- 8.5. Ossification of the Vertebral Column
- 8.6. Vertebral Column Anomalies
- 8.7. Development of the Atlas, Axis, Ribs, and Sternum
- 8.8. Bone Cells and Bone Deposition
- 8.9. Histology of Bone
- 8.10. Membrane Bone and Skull Development
- 8.11. Bone Development in Mesenchyme
- 8.12. Osteon Formation
- 8.13. Compact Bone Development and Remodeling
- 8.14. Endochondral Ossification in a Long Bone
- 8.15. Epiphyseal Growth Plate
- 8.16. Structure and Function of the Growth Plate
- 8.17. Pathophysiology of the Growth Plate
- 8.18. Ossification in the Newborn Skeleton
- 8.19. Joint Development
- 8.20. Muscular System: Primordia
- 8.21. Segmentation and Division of Myotomes
- 8.22. Epimere, Hypomere, and Muscle Groups
- 8.23. Development and Organization of Limb Buds
- 8.24. Limb Anomalies
- 8.25. Rotation of the Limbs
- 8.26. Limb Rotation and Dermatomes
- 8.27. Embryonic Plan of the Brachial Plexus
- 8.28. Divisions of the Lumbosacral Plexus
- 8.29. Developing Skeletal Muscles
- 9. Head and Neck
- 9.1. Timeline
- 9.2. Ectoderm, Endoderm, and Mesoderm
- 9.3. Pharyngeal (Branchial) Arches
- 9.4. Ventral and Midsagittal Views
- 9.5. Fate of the Pharyngeal Pouches
- 9.6. Midsagittal View of the Pharynx
- 9.7. Fate of the Pharyngeal Grooves
- 9.8. Pharyngeal Cyst, Sinus, and Fistula Formation
- 9.9. Summary of Pharyngeal Groove and Pouch Anomalies
- 9.10. Cranial Nerve Primordia
- 9.11. Cranial Nerve Neuron Components
- 9.12. Parasympathetic Innervation and Unique Nerves
- 9.13. Sensory Innervation Territories
- 9.14. Early Development of Pharyngeal Arch Muscles
- 9.15. Later Development of Pharyngeal Arch Muscles
- 9.16. Pharyngeal Arch Cartilages
- 9.17. Ossification of the Skull
- 9.18. Ossification of the Skull (Continued)
- 9.19. Premature Suture Closure
- 9.20. Cervical Ossification
- 9.21. Torticollis
- 9.22. Cervical Plexus
- 9.23. Orbit
- 9.24. Ear Development
- 9.25. Adult Ear Organization
- 9.26. Summary of Ear Development
- 9.27. Development of the Face: 3 to 4 Weeks
- 9.28. Development of the Face: 4 to 6 Weeks
- 9.29. Development of the Face: 6 to 10 Weeks
- 9.30. Holoprosencephaly
- 9.31. Palate Formation
- 9.32. Inferior View of Palate Formation, Roof of the Oral Cavity
- 9.33. Congenital Anomalies of the Oral Cavity
- 9.34. Floor of the Oral Cavity
- 9.35. Developmental Coronal Sections
- 9.36. Tooth Structure and Development
- 9.37. Dental Eruption
- Appendix. Summary of Common Congenital Anomalies Throughout the Body and their Embryonic Causes
- Index
- No. of pages: 320
- Language: English
- Edition: 2
- Published: September 22, 2023
- Imprint: Elsevier
- Paperback ISBN: 9780443117619
- eBook ISBN: 9780443117930
LC
Larry R. Cochard
Affiliations and expertise
The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA