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Neonatology Questions and Controversies: Renal, Fluid and Electrolyte Disorders
- 4th Edition - July 31, 2023
- Editors: John Lorenz, Michel G. Baum, Kathleen G. Brennan
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 7 8 7 7 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 7 9 4 3 - 9
Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering… Read more
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Request a sales quoteThe thoroughly updated, full-color, 4th Edition of Renal, Fluid, and Electrolyte Disorders:
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Provides a clear management strategy for common and rare neonatal renal, fluid, and electrolyte disorders, offering guidance based on the most up-to-date understanding of underlying pathophysiology.
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Places emphasis on controversial areas that can entail different approaches.
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Features the most current clinical information throughout, with many chapters written by new authors who offer a fresh perspective on key topics.
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Includes numerous new chapters, including assessment of neonatal kidney function, pulmonary hypoplasia in the fetus with oligohydramnios, genetic causes of congenital renal malformations, effect of preterm birth on renal outcomes, dialysis and kidney transplantation, renal tubular acidosis, and more.
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Highlights gaps in knowledge that should serve as a strong stimulus for future research.
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Utilizes a consistent chapter organization to help you find information quickly and easily, and contains numerous charts, graphs, radiographic images, and photographs throughout.
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Offers the most authoritative advice available from world-class neonatologists who share their knowledge of new trends and developments in neonatal care.
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An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Purchase each volume individually, or get the entire 7-volume Neonatology Questions and Controversies set, which includes online access that allows you to search across all titles!
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Gastroenterology and Nutrition
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Hematology and Transfusion Medicine
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Neonatal Hemodynamics
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Infectious Disease, Immunology, and Pharmacology
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Renal, Fluid, and Electrolyte Disorders
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Neurology
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The Newborn Lung
neonatologists, neonatal nurse practitioners, pediatricians
- Cover image
- Title page
- Table of Contents
- Other Volumes in the Neonatology Questions and Controversies Series
- Copyright
- Contributors
- Series Foreword
- Preface
- List of Illustrations
- List of Tables
- 1. Assessment of renal function in fetuses with lower urinary tract obstruction
- Introduction
- Prenatal diagnosis of lower urinary tract obstruction
- Antenatal predictors of postnatal renal function
- Prenatal procedural therapies
- Intrauterine renal failure concept
- Conclusion
- References
- 2. Assessment of neonatal kidney function
- Background
- Nephron development in utero
- Hereditary and in utero factors affecting nephron endowment
- Prematurity and nephrogenesis
- Adaptation of renal function in infancy in the first year of life
- Kidney function measurement in clinical practice
- Endogenous kidney function markers
- Small-molecular-weight proteins
- Exogenous methods
- Neonate-related issues of kidney function measurement
- Conclusions
- Acknowledgments
- References
- 3. Diagnosis and management of neonatal acute kidney injury
- Introduction
- Epidemiology and risk factors
- Clinical outcomes
- Assessment
- Preventative measures
- Management
- Long-term complications
- References
- 4. Pulmonary hypoplasia in the fetus with oligohydramnios: Causes, treatment, and prevention
- Introduction
- The link between kidney and lung development
- Amniotic fluid
- Pulmonary hypoplasia
- Treatment and prevention of pulmonary hypoplasia due to oligohydramnios
- Summary
- References
- 5. Pathophysiology and management of hyperkalemia in the neonate
- Intestinal potassium handling
- Extrarenal potassium regulation
- Renal potassium regulation
- Hyperkalemia in the neonate
- Evaluation of neonatal hyperkalemia
- Management of neonatal hyperkalemia
- References
- 6. Physiological management of fluid and electrolyte therapy in newborns
- Introduction
- Neonatal management is uniquely difficult
- Monitoring and management
- Sodium balance disorders
- Potassium disorders
- References
- 7. Pathophysiology and mana gement of hyponatremia and hypernatremia in the neonate
- Development of renal function and tubular transport
- Development of proximal tubule sodium reabsorption
- Proximal tubule water permeability
- Thin descending and thin ascending loops of henle
- Thick ascending limb of henle
- Distal convoluted tubule
- Collecting duct
- Developmental changes in collecting duct sodium transport
- Developmental changes in collecting duct water transport
- Dysnatremias
- Hyponatremia
- Pathophysiology of hyponatremia
- Extrarenal sodium loss
- Renal sodium loss
- Aldosterone deficiency and resistance disorders
- Salt losing tubulopathies
- Syndrome of inappropriate antidiuretic hormone
- Nephrogenic syndrome of inappropriate antidiuresis
- Hypernatremia
- Renal free water loss: Central and nephrogenic diabetes insipidus
- Extrarenal free water loss
- Feeding insufficiency
- References
- 8. Genetic causes of congenital anomalies of the kidney and urinary tract
- Introduction
- Evidence for genetic basis
- Renal development
- Spectrum of congenital anomalies of the kidney and urinary tract
- Future directions
- Conclusion
- References
- 9. Evidence-based approach to diuretic therapy in the neonate
- Introduction
- Developmental renal physiology and function
- Sodium reabsorption in the kidney
- Diuretic classes based upon mechanisms of action
- Clinical uses/indications for loop and thiazide diuretics
- Adverse effects of furosemide
- Novel diuretics, uses, and strategies
- Summary
- References
- 10. Effect of preterm birth on renal outcomes
- Introduction
- Nephrogenesis interrupted by preterm birth and physiologic adaptations
- Developmental programming of kidney and cardiovascular disease
- Oligonephronia: Kidney size as a surrogate marker for nephron mass
- Early nephron loss and accelerated aging of the kidney after preterm birth
- Multiple hit pathways from prematurity to chronic kidney disease: Short- and long-term risk factors
- Follow-up guidelines after neonatal intensive care unit discharge for prematurity-related kidney disease
- Summary
- References
- 11. Diagnosis and management of prenatal urinary tract dilatation
- Definitions and scope of prenatal urinary tract dilation
- Antenatal diagnosis of urinary tract dilation
- Effects of urinary tract dilation on the fetal kidney
- Prediction of postnatal outcome
- In utero intervention
- Postnatal evaluation and management of urinary tract dilation
- Special considerations in the postnatal management of urinary tract dilation
- Conclusions
- References
- 12. Dialysis and kidney transplantation in infancy
- Introduction
- Indications for kidney replacement therapy
- Ethical considerations for kidney replacement therapy in infants with chronic kidney disease
- Dialysis modalities
- Comorbidities associated with end-stage kidney disease
- Outcomes associated with infant dialysis
- Kidney transplantation in infancy
- Conclusion
- References
- 13. Renal tubular acidosis
- Renal acid-base regulation
- Renal tubular acidosis
- Laboratory testing in suspected renal tubular acidosis
- Long-term consequences of metabolic acidosis in infants with renal tubular acidosis
- References
- 14. Renal near-infrared spectroscopy use in the neonate
- Review of near-infrared spectroscopy
- Renal near-infrared spectroscopy sensor placement and monitoring techniques
- Normal renal saturation ranges
- Acute kidney injury: At-risk populations and early detection
- Renal near-infrared spectroscopy monitoring in other neonatal populations
- Future considerations
- References
- 15. Urosepsis and uroprophylaxis
- Introduction
- Epidemiology
- Diagnostic considerations
- Treatment
- Uroprophylaxis
- Antibiotic regimens for uroprophylaxis
- Long-term considerations for antimicrobial exposure
- References
- 16. Neonatal hypertension
- Introduction
- Normative values for neonatal blood pressure
- Incidence
- Differential diagnosis
- Clinical presentation
- Diagnostic evaluation
- Treatment
- Outcome
- Conclusions
- References
- Index
- No. of pages: 420
- Language: English
- Edition: 4
- Published: July 31, 2023
- Imprint: Elsevier
- Paperback ISBN: 9780323878777
- eBook ISBN: 9780323879439
JL
John Lorenz
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Michel G. Baum
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