Nanotechnology in Cancer Management
Precise Diagnostics toward Personalized Health Care
- 1st Edition - May 18, 2021
- Editors: Kamil Reza Khondakar, Ajeet Kumar Kaushik
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 8 1 5 4 - 6
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 8 1 5 5 - 3
Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early sta… Read more
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Request a sales quoteNanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions.
Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful.
- Includes smart sensing materials such as smart electro-active nanomaterials, sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical system, and device integration and interfacing for point-of-care applications
- Describes each component involved in the development of an efficient cancer diagnostics system
- Focuses on fundamental and applied concepts of the technologies, along with the related mechanisms proposed for diagnostics of cancer
- Enhances fundamental understandings of the concepts and development of nanotechnology based analytical tools and novel techniques for early stage cancer diagnostics and management
Post-graduates, researchers, and scientists in the field of chemistry, physics, biology, engineering, biomaterials, and medicine; medical professionals and others in interdisciplinary fields of science and technology as well as pharmaceutical materials synthesis and nanotechnology; industries involved in developing medical products and procedures
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- 1. Nanotechnology and its application: a review
- Abstract
- 1.1 Introduction
- 1.2 Application of nanotechnology
- 1.3 Conclusion
- 1.4 Future and challenges
- Acknowledgment
- References
- 2. Exploring biomarkers and diagnostics system for cancer management
- Abstract
- 2.1 Introduction
- 2.2 Efficient and miniaturized diagnostics system
- 2.3 Conclusion
- Acknowledgment
- Conflict of interest
- References
- 3. Electrochemical detection: Cyclic voltammetry/differential pulse voltammetry/impedance spectroscopy
- Abstract
- 3.1 Introduction
- 3.2 Matrix for immobilization of biorecognition molecule
- 3.3 Electrochemical transducers for cancer biomarker detection
- 3.4 Conclusions and outlooks
- Acknowledgments
- References
- 4. Fluorescence microscopy of organic dye, nanoparticles, quantum dots and spectroscopy
- Abstract
- 4.1 Introduction
- 4.2 Fluorescence spectroscopy
- 4.3 Fundamentals
- 4.4 Instrumentation
- 4.5 Fluorescence light sources
- 4.6 Nanoparticles and organic dyes for florescence sensors
- 4.7 Quantum dots for florescence imaging and cancer diagnostics
- 4.8 Cancer detection
- 4.9 Conclusion
- Acknowledgment
- Conflict of interest
- References
- 5. Raman spectroscopy/SERS based immunoassays for cancer diagnostics
- Abstract
- 5.1 Introduction
- 5.2 History and working principle
- 5.3 Application of Raman-active nanostructures
- 5.4 Surface-enhanced Raman spectroscopy platforms in cancer diagnostics
- 5.5 Other bioanalysis application: the notable application of Raman-based assays
- 5.6 Future challenges and conclusions
- Acknowledgment
- Conflict of interest
- References
- 6. Bioinformatics–computer programming
- Abstract
- 6.1 Introduction
- 6.2 Biological data
- 6.3 Cancer nanomedicine
- 6.4 Large-scale approaches to the study of cancer
- 6.5 Artificial intelligence
- 6.6 Programming language
- 6.7 Conclusion
- Acknowledgment
- Conflict of interest
- References
- 7. Magnetic-based sensing
- Abstract
- 7.1 Introduction
- 7.2 Magnetic sensors
- 7.3 Conclusions and outlook
- References
- 8. Microfluidics for early-stage cancer detection
- Abstract
- 8.1 Introduction
- 8.2 Blood-based cancer biomarkers and challenges in analysis
- 8.3 Fabrication of microfluidic biosensors
- 8.4 Microfluidics for cancer diagnosis
- 8.5 Conclusions
- References
- 9. Scale-up of rapid diagnostics for clinical applications: device development for clinical applications (oral cancer)
- Abstract
- 9.1 Introduction
- 9.2 Nanotechnology in cancer diagnosis
- 9.3 Nanotechnology in cancer therapy
- 9.4 Oral cancer challenges, limitations, safety issues, and ethical issues
- 9.5 Nanobiochip devices for clinical application
- 9.6 Future perspectives
- 9.7 Conclusions
- Acknowledgment
- Conflict of interest
- References
- 10. Challenges and future prospects of nano-enabled cancer management
- Abstract
- 10.1 Introduction
- 10.2 Immunotherapy approach
- 10.3 Detection of circulating tumor DNA/RNA
- 10.4 Extracellular vesicle analysis
- 10.5 Viewpoint
- Acknowledgment
- Conflict of interest
- References
- Index
- No. of pages: 252
- Language: English
- Edition: 1
- Published: May 18, 2021
- Imprint: Elsevier
- Paperback ISBN: 9780128181546
- eBook ISBN: 9780128181553
KR
Kamil Reza Khondakar
Dr. Kamil Reza Khondakar is a senior assistant Professor at Woxsen University, Hyderabad, India. He earned his Ph.D. from the Australian Institute for Bioengineering and Nanotechnology at The University of Queensland, Australia, where his research centered on developing microfluidic assays for detecting cancer biomarkers. He has edited 3 books and authored over 50 international research publications in the fields of lab-on-a-chip technology, electrochemical sensors, optical sensors, and machine learning assisted sensors for the advancement of personalized healthcare systems. He is also serving editorial roles for journal Frontiers in nanotechnology and Sensors (MDPI). He was awarded the Startup Research Grant (SRG-2023) by the Science & Engineering Research Board (SERB), Government of India, to develop microfluidic chip-based sensors for detecting water contamination. He also received International Postgraduate Research Scholarship (IPRS) from Government of Australia, and University of Queensland Centennial Scholarship (UQCent) from The University of Queensland, Australia. He was invited speaker at international conferences in USA, Australia and India. He has been affiliate member of the Royal Society of Chemistry since 2024 (invited).
Affiliations and expertise
School of Science,, Woxsen University, Kamkole, Telangana, IndiaAK
Ajeet Kumar Kaushik
Dr. Ajeet Kaushik is Associate Professor at the NanoBioTech Laboratory, Department of Environmental Engineering, Florida Polytechnic University, USA. He is the recipient of various reputed awards for his service in the area of nano-biotechnology for health care. He has edited seven books, written more than 100 international research peer reviewed publications, and has three patents in the area of nanomedicine and smart biosensors for personalized health care. In the course of his research, Dr. Kaushik has been engaged in the design and development of various electro-active nanostructures for electrochemical biosensor and nanomedicine for health care. His research interests include nanobiotechnology, analytical systems, design and develop nanostructures, nano-carries for drug delivery, nano-therapeutics for CNS diseases, on-demand site-specific release of therapeutic agents, exploring personalized nanomedicines, biosensors, point-of-care sensing devices, and related areas of health care monitoring.
Affiliations and expertise
Associate Professor of Chemistry, NanoBioTech Laboratory, Health System Engineering, Department of Environmental Engineering, Florida Polytechnic University, USARead Nanotechnology in Cancer Management on ScienceDirect