Nanostructured Materials for Tissue Engineering

1st Edition - August 24, 2023
Editors: Arijit Mondal, Amit Kumar Nayak, Prithviraj Chakraborty
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 1 3 4 - 0
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 5 1 3 5 - 7

Nanostructured Materials for Tissue Engineering introduces the key properties and approaches involved in using nanostructured materials in tissue engineering, including functi… Read more

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Nanostructured Materials for Tissue Engineering introduces the key properties and approaches involved in using nanostructured materials in tissue engineering, including functionalization, nanotechnology-based regenerative techniques, toxicological and biocompatible aspects. A broad range of nanomaterial types are covered, from polymer scaffolds and nanocomposites to gold nanoparticles and quantum dots. This book aids the reader in materials selection, as well as matching to the best applications, including bone, skin, pulmonary or neurological tissue engineering. Users will find this book to be an up-to-date review on this fast-changing field that is ideal for materials scientists, tissue engineers, biomedical engineers, and pharmaceutical scientists.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Section 1: Properties and approaches
1. Nanomaterials regenerative medicine and tissue engineering
Abstract
1.1 Introduction
1.2 Nanomaterial types, preparation, characterization, functionalization, and toxicology
1.3 Applications of nanomaterials in regenerative medicine
1.4 Applications of nanomaterials in tissue engineering
1.5 Applications of nanomaterials in neural tissue engineering
1.6 Applications of nanomaterials in bone tissue engineering
1.7 Applications of nanomaterials in skin tissue engineering
1.8 Applications of nanomaterials in drug delivery
1.9 Future perspectives
References
2. Advancement of nanoparticles in tissue engineering
Abstract
2.1 Introduction
2.2 A brief review of nanoparticles
2.3 Nanostructures utilization for tissue engineering scaffolds
2.4 Applications of nanoparticles in tissue engineering
2.5 Challenges and future perspectives
2.6 Conclusion
References
3. Functionalization of nanoparticles in tissue engineering
Abstract
3.1 Introduction
3.2 Importance of functionalization of nanoparticles (Aravind et al., 2012; Thiruppathi et al., 2017)
3.3 Phyto-nanoparticles in tissue engineering
3.4 Metallic nanoparticles in tissue engineering
3.5 Marketed nanoparticle
3.6 Conclusion
References
4. Application of nanorange self-assembly in tissue engineering
Abstract
4.1 Introduction
4.2 Self-assembly
4.3 Design of self-assembled nanoparticles
4.4 Self-assembled nanoparticles as a biosensor platform
4.5 Nanoparticles self-assembly for bioimaging uses
4.6 Nanoassemblies based on proteins for biomedical uses
4.7 Tissue engineering by self-assembling
4.8 Application of nanofibres in tissue engineering
4.9 Alumina nanofibers: uses in tissue engineering
4.10 Conclusion
References
5. Nanotechnology-based regenerative approaches
Abstract
5.1 Nanotechnological approach in bone and cartilage regeneration
5.2 Nanotechnological approach in cardiac tissue regeneration
5.3 Application of nanotechnology in cardiac tissue regeneration
5.4 Nanotechnological approach in neuron regeneration
5.5 Application of nanotechnology in nerve tissue regeneration
5.6 Nanotechnological approach in liver regeneration
5.7 Stem cell delivery
5.8 Nanotechnological approach in kidney regeneration
5.9 Biomimicking nanostructures
5.10 Nanotechnological approach in vascular regeneration
5.11 Early tissue-engineered blood vessels
5.12 Fabrication techniques
5.13 Biomaterials sources
5.14 Clinical applications
5.15 Engineering of microvessels
5.16 Endothelial characterization
5.17 Future directions
5.18 Nanotechnological approach for skin tissue regeneration
5.19 Tissue engineering
References
6. Toxicology of nanoformulations and materials in tissue engineering
Abstract
6.1 Introduction
6.2 Gold nanoparticles
6.3 Ceramic nanoparticles
6.4 Magnetic nanoparticles
6.5 Polymeric nanoparticles
6.6 Delivery of bioactive substances
6.7 Imaging and contrast agents
6.8 Nanoparticles in bioinks for three-dimensional printing
6.9 Nanotoxicology
6.10 Conclusion
References
7. Biocompatibility of nanomaterials for tissue engineering
Abstract
7.1 Introduction
7.2 Biocompatibility of nanomaterials
7.3 Tissue engineering through the nanomaterials
7.4 Metallic nanoparticles in tissue engineering
7.5 Polymeric nanoparticle in tissue engineering
7.6 Application of nanomaterials in bone and cartilage tissue engineering
7.7 Application of nanomaterials in vascular and nerve tissue engineering
7.8 Future perspective of nanomaterials in tissue engineering
7.9 Conclusion
References
Section 2: Nanomaterials
8. Biopolymer nanocomposites and membranes in tissue engineering
Abstract
8.1 Introduction
8.2 Naturally derived biopolymer nanocomposite and membranes in tissue engineering
8.3 Synthetic biopolymer nanocomposites and membranes
8.4 Toxicity and safety regulations of nanocomposites and membranes
8.5 Conclusion
References
9. Boron nitride nanostructures in tissue engineering
Abstract
9.1 Introduction
9.2 Manufacturing method of boron nitride nanotubes
9.3 Properties of hexagonal boron nitride
9.4 Applications
9.5 Safety assessment of boron nitride nanotubes
9.6 Conclusion and future prospect
References
10. Quantum dots in tissue engineering
Abstract
10.1 Introduction
10.2 Synthesis
10.3 Structure of quantum dots
10.4 Optical properties of quantum dots
10.5 Applications of quantum dots
10.6 Conclusion and future prospect
References
11. Gold nanoparticles in tissue engineering
Abstract
11.1 Introduction
11.2 Various Synthetic method
11.3 Conventional chemical method of synthesis
11.4 Applications
11.5 Disadvantages of nanoparticles
11.6 Conclusion
References
Section 3: Applications
12. Nanoparticles in bone tissue engineering
Abstract
12.1 Introduction
12.2 Bone tissue engineering
12.3 Strategies to improve bone tissue engineering
12.4 Challenges in bone tissue engineering
12.5 Nanotechnology in tissue engineering
12.6 Biomaterials
12.7 Nanoparticles
12.8 Carbon nanotubes
12.9 Quantum dots
12.10 Nanofibers
12.11 Pros and cons
12.12 Applications
12.13 Conclusion
References
13. Nanostructured materials for dental tissue engineering
Abstract
13.1 Introduction
13.2 Stem cells in periodontal and dental tissues used in dentistry
13.3 Nanostructured materials use for tissue engineering in dentistry
13.4 Nanomaterials in experimental dentistry studies
13.5 Summary
13.6 Conclusions
Conflicts of interest
Abbreviations
References
14. Nanoparticles for triggering gene expression and osteoconductivity
Abstract
14.1 Introduction
14.2 Different varieties of nanoparticles
14.3 Nanoparticles in gene expression
14.4 Future standpoints on nanoparticles triggering gene expression
14.5 Conclusion
References
15. Nanomaterials for skin repair and regeneration
Abstract
15.1 Introduction
15.2 Components deliver for wound healing and skin regeneration
15.3 Physiology of wound healing
15.4 Distinguished classes and types of nanomaterials
15.5 Nanomaterials in skin repair and regeneration
15.6 Conclusion
References
16. Nanomaterial scaffolds for cardiovascular tissue engineering
Abstract
16.1 Introduction
16.2 Nanoengineered surfaces in cardiac regeneration
16.3 Approaches of nanoengineered scaffolds
16.4 Interaction of myocardium components with nanoengineered scaffolds
16.5 Future prospects and conclusion
Conflicts of interest
References
17. Nanotechnology in pulmonary tissue engineering
Abstract
17.1 Introduction
17.2 Tissue engineering for pulmonary disease
17.3 Conclusion
References
18. Nanotechnology in tissue engineering for diabetes management
Abstract
18.1 Introduction
18.2 Tissue engineering from nanotechnology
18.3 Electrospun nanofibers
18.4 Surfaces with nanotextures for tissue engineering
18.5 Application to tissue engineering
18.6 Diabetes mellitus
18.7 Conclusion
References
19. Nanoscale drug delivery and tissue engineering for neurodegenerative diseases
Abstract
19.1 Introduction
19.2 Tissue engineering and its objective in neurodegenerative diseases
19.3 Three-dimensional tissue models in neurodegenerative diseases
19.4 Immobilized drug delivery options
19.5 Nano-enabled drug delivery systems
19.6 Nanodelivery of drugs for Alzheimer’s disease
19.7 Nanodelivery of drugs for Parkinson’s disease
References
Index

Arijit Mondal

Dr Arijit Mondal has received his PhD in Pharmacy from Jadavpur University, Kolkata, India, in the year 2012. He has completed his Postdoctoral research training from CSIR-Indian Institute of Chemical Biology, Kolkata, India. His major areas of research interest include cancer therapeutics, drug development and characterization and mechanism of action of optimized drug delivery systems. Till date he has authored more than 37 publications in various high impact peer-reviewed journals, and 2 book chapters to his credit. He is also serving as an Editorial Board member of several reputed journals in the field of Pharmaceutical Sciences. Dr Mondal has also participated and presented his research work in different national and international conferences in India, USA, and Thailand, and received grants from different agencies like CSIR, ICMR, DST to present his research work in conferences.

Affiliations and expertise

Professor, Department of Pharmaceutical Chemistry, Bengal College of Pharmaceutical Technology, Dubrajpur, West Bengal, India

Amit Kumar Nayak

Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.

Affiliations and expertise

Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India

Prithviraj Chakraborty

Dr. Chakraborty has received his Ph.D in the year 2014 and has more than 13 years of experience in pharmacy education at Post graduate, degree and diploma level institutions. He has more than 22 papers to his credit in International journals of repute. He has presented his research findings as 17 posters in National and International conferences, attended many National and International Seminars, Symposia & workshops. He is a life member of Association of Pharmaceutical Teachers of India (APTI). He serves as the reviewer of several reputed journals also. He has also contributed chapters in edited volumes of books published by different international publishers of repute like John Wiley Publishing LLC, CRC Press, Elsevier, and Basera Verlag.

Affiliations and expertise

Professor, Royal School of Pharmacy, The Assam Royal Global University, Assam, India