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Elsevier

Muscle Biopsy: A Practical Approach

Expert Consult; Online and Print

  • 4th Edition - February 8, 2013
  • Latest edition
  • Authors: Victor Dubowitz, Caroline A. Sewry, Anders Oldfors
  • Language: English

2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effective… Read more

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2014 BMA Medical Book Awards Highly Commended in Pathology category!

Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence

"Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology" Reviewed by The Bulletin of The Royal College of Pathologists, Jan 2015

Key features

  • Bridge the gap between clinical syndromes/disorders and their underlying
    •  pathologies with the guidance of muscle disease expert, Dr. Victor Dubowitz, who skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment.
  • Understand and apply expert techniques for obtaining a muscle biopsy, and familiarize yourself with the histochemical, histological, electron microscopical, and molecular appearance of normal muscle and the pathology of individual muscle disease.
  • Read the entire contents and download all of the images online at Expert Consult.

Readership

Neuropathologists, Neurologists, Pathologists, Residents, Fellows, and Health Science Libraries

Table of contents

Section 1 The Biopsy: Normal and Diseased Muscle1. The procedure of muscle biopsy2. Histological and histochemical stains and reactions3. Normal muscle4. Definition of pathological changes seen in muscle biopsies5. Ultrastructural changes in diseased muscle6. Immunohistochemistry 7. How to read a biopsySection 2 Pathological Muscle: Individual Diseases8. Classification of neuromuscular disorders9. Neurogenic disorders10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies13. Muscular dystrophies and allied disorders IV: Emeryƒ{Driefuss muscular dystrophies and Bethlem myopathy14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy15. Congenital myopathies16. Myofibrillar myopathies17. Metabolic myopathies I: glycogenoses18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies19. Endocrine disorders20. Ion channel disorders21. Myasthenic syndromes22. Inflammatory myopathies23. Toxic and drug-induced myopathies Russell Lane, Charing Cross HospitalAppendix 1. Glossary of commonly used termsReferencesIndex

Review quotes

"The third edition of this book...has surpassed my expectations. The quality of the book overall is excellent, from the production and layout to the illustrations, diagrams and index. The range of muscle diseases included spans both adults and children, with an integrated approach to diagnosis including clinical, genetic, biochemical and pathological features. Overall, this book has been a highlight of the past year for me. It deserves to do very well indeed and will be of immense value beyond its target readership." BMA Awards 2007

"The book is aimed at diagnostic pathologists and the authors have made a sensible and valid attempt to harmonise classical nomenclature with the new advances in genetics that threaten to overturn previous attempts at classifying muscle disease.Overall, this is a well written and comprehensive textbook of muscle pathology that will be of invaluable assistance to laboratories reporting muscle pathology."Reviewed by: Dr Ian S Scott Consultant Neuropathologist Queen’s Medical Centre Nottingham Date: Jan 2015

Product details

  • Edition: 4
  • Latest edition
  • Published: February 8, 2013
  • Language: English

About the authors

VD

Victor Dubowitz

Affiliations and expertise
Emeritus Professor of Paediatrics Dubowitz Neuromuscular Centre Institute of Child Health London, UK

CS

Caroline A. Sewry

Affiliations and expertise
Professor of Muscle Pathology Dubowitz Neuromuscular Centre Institute of Child Health/Great Ormond Street Hospital for Children London, UK; Wolfson Centre for Inherited Neuromuscular Diseases Department of Musculoskeletal Pathology Robert Jones and Agnes Hunt Orthopaedic Hospital Oswestry, UK

AO

Anders Oldfors

Affiliations and expertise
Professor of Pathology Sahlgrenska Academy University of Gothenburg Gothenburg, Sweden

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