Muscle Biology
The Life History of a Muscle
- 1st Edition - November 28, 2021
- Imprint: Academic Press
- Author: Bruce M. Carlson
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 0 2 7 8 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 0 2 7 9 - 1
Muscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumsta… Read more
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Request a sales quoteMuscle Biology: The Life History of a Muscle looks at the story of a muscle from its embryonic beginnings, through its growth and ability to adapt to changing functional circumstances during adult life, to its eventual decline in both structure and function as old age progresses. Injury occurs to muscle during normal activity, after trauma, and during the source of certain diseases. Chapters on both muscle regeneration and muscle diseases emphasize the possibilities and limitsations of the healing capacity of muscle fibers.
Muscle Biology begins with a brief review about the structure and function of a normal mature muscle and then proceeds to follow the developmental history of a muscle from the embryo to old age in a manner that gives the reader a perspective about not only developmental controls but also how at any stage of development a muscle is able to adapt to its functional environment. The book discusses both normal and abnormal changes in the muscle, the mechanisms behind those changes and how to mitigate deleterious changes from disease, 'normal' aging, and disuse/lack of physical activity. This is a must-have reference for students, researchers and practitioners in need of a comprehensive overview of muscle biology.
- Provides an overview of muscle biology over the course of one’s entire lifespan
- Explains the important elements of each aspect of muscle biology without drowning the reader in excessive detail
- Contains over 300 illustrations and includes chapter summaries
Upper undergraduate, graduates, postdocs, professors and researchers studying biology, anatomy, physiology, developmental biology, pathophysiology, aging/gerontology, kinesiology/movement science and those across the life sciences interested in muscles/muscle biology as well as practitioners in physical therapy and occupational therapy
- Cover image
- Title page
- Table of Contents
- Copyright
- Sources of borrowed figures
- Preface
- Introduction
- Chapter 1. Mature skeletal muscle—An overview
- The many structural dimensions of muscle
- The neuromuscular junction
- Muscle fiber contraction
- Contractile properties of single muscle fibers and muscle fiber types
- Motor units
- The sensory apparatus of a muscle
- Contraction of an entire muscle
- The role of internal architecture in muscle function
- The role of connective tissue in whole muscle contraction
- Tendons and their connection to muscle and bone
- Muscle contractions and whole-body movements
- Chapter 2. Embryonic origins of skeletal muscle
- Origins and cellular migrations
- Morphogenesis of a muscle
- Myogenesis
- Chapter 3. Normal muscle growth
- Prenatal muscle fiber formation
- Development of muscle fiber types
- Satellite cells and postnatal muscle growth
- Myostatin and the control of muscle growth
- The intrauterine and early postnatal growth environment for muscle
- Systemic factors influencing intrauterine and early postnatal growth
- Chapter 4. Muscle adaptation to increased use
- Muscle adaptations to increased load (strength training) or increased duration of use (endurance training)
- Adaptations to increased duration of use (endurance exercise)
- Chapter 5. Muscle adaptation to decreased use
- Conditions leading to muscle atrophy
- The metabolic and molecular basis of muscular atrophy
- Chapter 6. Muscle injury and regeneration
- The epimorphic regeneration of skeletal muscle
- The tissue regeneration of skeletal muscle
- Chapter 7. Muscle disorders
- Disorders of muscle fibers
- Other disorders affecting muscles
- Chapter 8. The aging of muscle
- Broad measures of aging effects on skeletal muscle
- The structural basis for muscle loss during aging
- Performance measures of aging muscle
- Neuromuscular interactions in aging muscle
- Sarcopenia
- Satellite cells and muscle regeneration in old age
- Effects of exercise in old age
- Index
- Edition: 1
- Published: November 28, 2021
- No. of pages (Paperback): 212
- No. of pages (eBook): 212
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780128202784
- eBook ISBN: 9780128202791
BC
Bruce M. Carlson
Bruce M. Carlson, MD, PhD, is Professor Emeritus of Anatomy in the Department of Cell and Developmental Biology in the University of Michigan Medical School in Ann Arbor. He served as chair of that department from 1998-2000. He is also Research Professor Emeritus in the school’s Institute of Gerontology, of which he was the director from 2000 to 2003. Professor Carlson writes the majority of the book himself but he has suggested that he may bring in one or two contributors this time round to cover areas that he is not as up to date on as he once was. We have spoken about bringing in a co-author and he is open for this to happen for the 7th edition when he has had time to find someone suitable.
Affiliations and expertise
Professor, Department of Cell and Developmental Biology; Director, Institute of Gerontology, University of Michigan, Ann Arbor, MI, USARead Muscle Biology on ScienceDirect