Murray & Nadel's Textbook of Respiratory Medicine, 2-Volume Set
- 8th Edition - October 15, 2026
- Latest edition
- Editors: V. Courtney Broaddus, Nirav R. Bhakta, Joel D. Ernst, Talmadge E. King Jr, Kathleen F. Sarmiento, Lynn M. Schnapp, Renee D. Stapleton
- Language: English
Covering the entire spectrum of pulmonology in one authoritative point-of-care resource, Murray & Nadel's Textbook of Respiratory Medicine, 8th Edition, remains the go-t… Read more
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Description
Description
Covering the entire spectrum of pulmonology in one authoritative point-of-care resource, Murray & Nadel's Textbook of Respiratory Medicine, 8th Edition, remains the go-to clinical guide and training reference for pulmonary physicians, fellows, and other pulmonary practitioners. Edited and authored by pulmonary experts at the top of their field, it offers definitive, well written, full-color coverage of foundational content, basic science, diagnostic strategies, clinical decision-making, and evidence-based treatment, making it highly relevant for both trainees and seasoned clinicians. This edition includes important new chapters and updates, a streamlined and integrated approach to content, and new author teams that bring fresh perspectives to areas like asthma and COPD management, lung cancer molecular biology and targeted therapies, pleural effusions, interstitial lung disease, and outpatient/inpatient ventilator strategies—enhanced with digital tools and online resources for continuous learning and clinical reference.
Key features
Key features
- Provides detailed explanations of each disease entity and differential diagnoses with clinical decision-making guidance, evidence-based content, and diagnostic algorithms, authored by global leaders in the field
- Reflects the latest advances in respiratory medicine throughout, including diagnostic innovations, breakthrough therapies, and updated clinical guidelines, supporting real-world application and life-long learning
- Includes new chapters on medical education, pulse oximetry and capnography, obesity hypoventilation, and both noninvasive and invasive ventilation strategies for chronic respiratory failure, as well as extensively revised content on community-acquired pneumonia, sleep disorders, and critical illness—optimized for clinical practice
- Features more than 1,450 anatomic, algorithmic, and radiologic images, including CT/HRCT, MR, and PET, plus extensive online content: 200 procedural and conceptual videos, audio clips of lung sounds, and new instructional videos on bronchoscopy techniques for self-assessment and clinical training
- Includes succinct Key Point summaries for each chapter, useful for self-directed learning, self-study exam preparation, and clinical reference
- Integrates the scientific foundation and genetics into disease-specific chapters for comprehensive understanding and clinical application
- Brings you up to date with the latest respiratory drugs, mechanisms of action, indications, precautions, adverse effects, and clinical guidelines supported by online resources for ongoing education
- Sets pulmonary fellows up for success with comprehensive coverage aligned with fellowship curricula—the core knowledge you need to pass your licensing exam and understand the broad range of respiratory medicine for your future career
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date
Readership
Readership
Pulmonologists, critical care specialists, and pulmonary fellows who require a comprehensive, evidence-based reference that aligns with fellowship curricula and supports both clinical practice and exam preparation
Table of contents
Table of contents
VOLUME 1
Part 1: Scientific Principles of Pulmonary Medicine
Section A: Anatomy and Development of the Respiratory Tract
Chapter 1: Anatomy: Structure and Cells
Chapter 2: Lung Growth and Development
Chapter 3: Alveolar Compartment
Chapter 4: Airway Biology
Chapter 5: The Lung Mesenchyme
Chapter 6: Vascular Biology
Chapter 7: Lymphatic Biology
Chapter 8: Stem Cells and Regeneration
Section B: Respiratory Physiology
Chapter 9: Ventilation, Blood Flow, and Gas Exchange
Chapter 10: Respiratory System Mechanics and Energetics
Chapter 11: Acid-Base Balance
Chapter 12: Aerosols and Drug Delivery
Chapter 13: Control of Breathing and Pathophysiology of Sleep Apnea
Chapter 14: Pleural Physiology and Pathophysiology
Section C: Defense Mechanisms and Immunology
Chapter 15: Innate and Adaptive Immunity
Chapter 16: Microbiome
Part 2: Diagnosis and Evaluation of Respiratory Disease
Section D: Diagnosis
Chapter 17: History and Physical Examination
Chapter 18: Microbiologic and Molecular Diagnosis of Lung Infection
Chapter 19: Thoracic Radiology: Noninvasive Diagnostic Imaging
Chapter 20: Thoracic Radiology: Invasive Diagnostic Imaging and Image-Guided Interventions
Chapter 21: Pathology: Neoplastic and Nonneoplastic Lung Disease
Chapter 22: Ultrasonography: Point-of-Care Principles, Vascular Imaging, and Thoracic Imaging
Chapter 23: Ultrasonography: Point of Care Evaluation of Cardiac Function and Shock
Chapter 24: Positron Emission Tomography
Chapter 25: Diagnostic Bronchoscopy: Basic Techniques
Chapter 26: Diagnostic Bronchoscopy: Advanced Techniques (EBUS and Navigational)
Chapter 27: Therapeutic Bronchoscopy
Chapter 28: Thoracoscopy
Chapter 29: Thoracic Surgery
Section E: Evaluation
Chapter 30: Pulmonary Function Testing: Principles
Chapter 31: Pulmonary Function Testing: Interpretation and Applications
Chapter 32: Pulse Oximetry and Capnography
Chapter 33: Exercise Testing
Chapter 34: Preoperative Evaluation
Chapter 35: Evaluation of Respiratory Impairment and Disability
Part 3: Clinical Respiratory Medicine
Section F: Evaluation of Common Presentations of Respiratory Disease
Chapter 36: Dyspnea
Chapter 37: Cough
Chapter 38: Chest Pain
Chapter 39: Wheezing and Stridor
Chapter 40: Hemoptysis
Chapter 41: Pulmonary Nodule
Chapter 42: Aspiration
Chapter 43: Pulmonary Edema
Chapter 44: Hypoxemia
Chapter 45: Hypercapnia
Section G: Infectious Diseases of the Lungs
Chapter 46: Community-Acquired Pneumonia: General Features
Chapter 47: Community-Acquired Pneumonia: Specific Pathogens (Including Severe Acute Respiratory Syndrome Coronavirus 2)
Chapter 48: Influenza
Chapter 49: Hospital-Acquired Pneumonia
Chapter 50: Ventilator-Associated Pneumonia
Chapter 51: Lung Abscess
Chapter 52: Tuberculosis: Epidemiology and Prevention
Chapter 53: Tuberculosis: Pathogenesis and Immunity
Chapter 54: Tuberculosis: Clinical Manifestations and Diagnosis
Chapter 55: Tuberculosis: Treatment of Drug-Susceptible and Drug-Resistant
Chapter 56: Nontuberculous Mycobacterial Infections
Chapter 57: Fungal Infections: Endemic
Chapter 58: Fungal Infections: Opportunistic
Chapter 59: Parasitic Infections
Chapter 60: Outbreaks, Pandemics, and Bioterrorism
Section H: Obstructive Diseases
Chapter 61: Asthma: Pathogenesis and Phenotypes
Chapter 62: Asthma and Obesity
Chapter 63: Asthma: Diagnosis and Management
Chapter 64: COPD: Pathogenesis and Natural History
Chapter 65: COPD: Diagnosis and Management
Chapter 66: Smoking Hazards: Cigarettes, Vaping, and Marijuana
Chapter 67: Tobacco Use Disorder: Treatment
Chapter 68: Cystic Fibrosis: Pathogenesis and Epidemiology
Chapter 69: Cystic Fibrosis: Diagnosis and Management
Chapter 70: Bronchiectasis
Chapter 71: Upper Airway Disorders
Chapter 72: Large Airway Disorders
Chapter 73: Bronchiolitis
VOLUME 2
Section I: Neoplasms of the Lungs
Chapter 74: Lung Cancer: Molecular Biology and Targets
Chapter 75: Lung Cancer: Epidemiology
Chapter 76: Lung Cancer: Screening
Chapter 77: Lung Cancer: Diagnosis and Staging
Chapter 78: Lung Cancer: Treatment
Chapter 79: Rare Primary Lung Tumors
Chapter 80: Metastatic Malignant Tumors
Chapter 81: Benign Lung Tumors
Section J: Disorders of Pulmonary Circulation
Chapter 82: Pulmonary Thromboembolism: Presentation and Diagnosis
Chapter 83: Pulmonary Thromboembolism: Prophylaxis and Treatment
Chapter 84: Pulmonary Hypertension: General Approach
Chapter 85: Pulmonary Arterial Hypertension: Group 1
Chapter 86: Pulmonary Hypertension Due to Lung Disease: Group 3
Chapter 87: Pulmonary Hypertension Due to Chronic Thromboembolic Disease: Group 4
Chapter 88: Pulmonary Vasculitis
Chapter 89: Pulmonary Vascular Anomalies
Section K: Infiltrative and Interstitial Lung Diseases
Chapter 90: Idiopathic Pulmonary Fibrosis
Chapter 91: Nonspecific Interstitial Pneumonitis and Other Idiopathic Interstitial Pneumonias
Chapter 92: Hypersensitivity Pneumonitis
Chapter 93: Connective Tissue Diseases
Chapter 94: Sarcoidosis
Chapter 95: Diffuse Alveolar Hemorrhage
Chapter 96: Pulmonary Langerhans Cell Histiocytosis and Rare Infiltrative Diseases
Chapter 97: Eosinophilic Lung Diseases
Chapter 98: Lymphangioleiomyomatosis and Other Cystic Lung Diseases
Chapter 99: Pulmonary Alveolar Proteinosis Syndrome
Chapter 100: Drug-Induced Pulmonary Disease
Section L: Environmental and Occupational Hazards
Chapter 101: Asthma in the Workplace
Chapter 102: Pneumoconioses
Chapter 103: Indoor and Outdoor Air Pollution
Chapter 104: Acute Pulmonary Responses to Toxic Exposures
Chapter 105: Trauma and Blast Injuries
Chapter 106: High Altitude
Chapter 107: Air Travel
Chapter 108: Diving Medicine
Section M: Disorders of the Pleura
Chapter 109: Pleural Effusion
Chapter 110: Pleural Infections
Chapter 111: Pneumothorax
Chapter 112: Chylothorax
Chapter 113: Pleural Fibrosis and Nonexpandable Lung
Chapter 114: Hemothorax
Chapter 115: Pleural Malignancy
Section N: Disorders of the Mediastinum
Chapter 116: Mediastinal Tumors and Cysts
Chapter 117: Mediastinitis and Fibrosing Mediastinitis
Section O: Respiratory Manifestations of Extrapulmonary Disorders
Chapter 118: Pulmonary Complications of HIV Infection
Chapter 119: Pulmonary Complications of Primary Immunodeficiencies
Chapter 120: Pulmonary Complications of Stem Cell and Solid Organ Transplantation
Chapter 121: Pulmonary Complications of Abdominal Diseases
Chapter 122: Pulmonary Complications of Hematologic Diseases
Chapter 123: Pulmonary Complications of Endocrine Diseases
Chapter 124: The Lungs in Obstetric and Gynecologic Diseases
Chapter 125: The Respiratory System and Neuromuscular Diseases
Chapter 126: The Respiratory System and Chest Wall Diseases
Section P: Disorders of Sleep and Control of Breathing
Chapter 127: Consequences of Sleep Disruption
Chapter 128: Sleep-Disordered Breathing: A General Approach
Chapter 129: Obstructive Sleep Apnea
Chapter 130: Central Sleep Apnea
Chapter 131: Obesity Hypoventilation Syndrome
Chapter 132: Sleep-Disordered Breathing: Treatment
Section Q: Management of Respiratory Failure
Chapter 133: Acute Ventilatory Failure
Chapter 134: Acute Respiratory Distress Syndrome
Chapter 135: Mechanical Ventilation
Chapter 136: Noninvasive Ventilation for Acute Respiratory Failure
Chapter 137: Noninvasive and Invasive Ventilation for Chronic Respiratory Failure
Chapter 138: Noninvasive Support of Oxygenation
Chapter 139: Extracorporeal Support of Gas Exchange
Chapter 140: Pulmonary Rehabilitation
Chapter 141: Lung Transplantation
Chapter 142: End-of-Life Care in Respiratory Failure
Chapter 143: Medical Education
Part 1: Scientific Principles of Pulmonary Medicine
Section A: Anatomy and Development of the Respiratory Tract
Chapter 1: Anatomy: Structure and Cells
Chapter 2: Lung Growth and Development
Chapter 3: Alveolar Compartment
Chapter 4: Airway Biology
Chapter 5: The Lung Mesenchyme
Chapter 6: Vascular Biology
Chapter 7: Lymphatic Biology
Chapter 8: Stem Cells and Regeneration
Section B: Respiratory Physiology
Chapter 9: Ventilation, Blood Flow, and Gas Exchange
Chapter 10: Respiratory System Mechanics and Energetics
Chapter 11: Acid-Base Balance
Chapter 12: Aerosols and Drug Delivery
Chapter 13: Control of Breathing and Pathophysiology of Sleep Apnea
Chapter 14: Pleural Physiology and Pathophysiology
Section C: Defense Mechanisms and Immunology
Chapter 15: Innate and Adaptive Immunity
Chapter 16: Microbiome
Part 2: Diagnosis and Evaluation of Respiratory Disease
Section D: Diagnosis
Chapter 17: History and Physical Examination
Chapter 18: Microbiologic and Molecular Diagnosis of Lung Infection
Chapter 19: Thoracic Radiology: Noninvasive Diagnostic Imaging
Chapter 20: Thoracic Radiology: Invasive Diagnostic Imaging and Image-Guided Interventions
Chapter 21: Pathology: Neoplastic and Nonneoplastic Lung Disease
Chapter 22: Ultrasonography: Point-of-Care Principles, Vascular Imaging, and Thoracic Imaging
Chapter 23: Ultrasonography: Point of Care Evaluation of Cardiac Function and Shock
Chapter 24: Positron Emission Tomography
Chapter 25: Diagnostic Bronchoscopy: Basic Techniques
Chapter 26: Diagnostic Bronchoscopy: Advanced Techniques (EBUS and Navigational)
Chapter 27: Therapeutic Bronchoscopy
Chapter 28: Thoracoscopy
Chapter 29: Thoracic Surgery
Section E: Evaluation
Chapter 30: Pulmonary Function Testing: Principles
Chapter 31: Pulmonary Function Testing: Interpretation and Applications
Chapter 32: Pulse Oximetry and Capnography
Chapter 33: Exercise Testing
Chapter 34: Preoperative Evaluation
Chapter 35: Evaluation of Respiratory Impairment and Disability
Part 3: Clinical Respiratory Medicine
Section F: Evaluation of Common Presentations of Respiratory Disease
Chapter 36: Dyspnea
Chapter 37: Cough
Chapter 38: Chest Pain
Chapter 39: Wheezing and Stridor
Chapter 40: Hemoptysis
Chapter 41: Pulmonary Nodule
Chapter 42: Aspiration
Chapter 43: Pulmonary Edema
Chapter 44: Hypoxemia
Chapter 45: Hypercapnia
Section G: Infectious Diseases of the Lungs
Chapter 46: Community-Acquired Pneumonia: General Features
Chapter 47: Community-Acquired Pneumonia: Specific Pathogens (Including Severe Acute Respiratory Syndrome Coronavirus 2)
Chapter 48: Influenza
Chapter 49: Hospital-Acquired Pneumonia
Chapter 50: Ventilator-Associated Pneumonia
Chapter 51: Lung Abscess
Chapter 52: Tuberculosis: Epidemiology and Prevention
Chapter 53: Tuberculosis: Pathogenesis and Immunity
Chapter 54: Tuberculosis: Clinical Manifestations and Diagnosis
Chapter 55: Tuberculosis: Treatment of Drug-Susceptible and Drug-Resistant
Chapter 56: Nontuberculous Mycobacterial Infections
Chapter 57: Fungal Infections: Endemic
Chapter 58: Fungal Infections: Opportunistic
Chapter 59: Parasitic Infections
Chapter 60: Outbreaks, Pandemics, and Bioterrorism
Section H: Obstructive Diseases
Chapter 61: Asthma: Pathogenesis and Phenotypes
Chapter 62: Asthma and Obesity
Chapter 63: Asthma: Diagnosis and Management
Chapter 64: COPD: Pathogenesis and Natural History
Chapter 65: COPD: Diagnosis and Management
Chapter 66: Smoking Hazards: Cigarettes, Vaping, and Marijuana
Chapter 67: Tobacco Use Disorder: Treatment
Chapter 68: Cystic Fibrosis: Pathogenesis and Epidemiology
Chapter 69: Cystic Fibrosis: Diagnosis and Management
Chapter 70: Bronchiectasis
Chapter 71: Upper Airway Disorders
Chapter 72: Large Airway Disorders
Chapter 73: Bronchiolitis
VOLUME 2
Section I: Neoplasms of the Lungs
Chapter 74: Lung Cancer: Molecular Biology and Targets
Chapter 75: Lung Cancer: Epidemiology
Chapter 76: Lung Cancer: Screening
Chapter 77: Lung Cancer: Diagnosis and Staging
Chapter 78: Lung Cancer: Treatment
Chapter 79: Rare Primary Lung Tumors
Chapter 80: Metastatic Malignant Tumors
Chapter 81: Benign Lung Tumors
Section J: Disorders of Pulmonary Circulation
Chapter 82: Pulmonary Thromboembolism: Presentation and Diagnosis
Chapter 83: Pulmonary Thromboembolism: Prophylaxis and Treatment
Chapter 84: Pulmonary Hypertension: General Approach
Chapter 85: Pulmonary Arterial Hypertension: Group 1
Chapter 86: Pulmonary Hypertension Due to Lung Disease: Group 3
Chapter 87: Pulmonary Hypertension Due to Chronic Thromboembolic Disease: Group 4
Chapter 88: Pulmonary Vasculitis
Chapter 89: Pulmonary Vascular Anomalies
Section K: Infiltrative and Interstitial Lung Diseases
Chapter 90: Idiopathic Pulmonary Fibrosis
Chapter 91: Nonspecific Interstitial Pneumonitis and Other Idiopathic Interstitial Pneumonias
Chapter 92: Hypersensitivity Pneumonitis
Chapter 93: Connective Tissue Diseases
Chapter 94: Sarcoidosis
Chapter 95: Diffuse Alveolar Hemorrhage
Chapter 96: Pulmonary Langerhans Cell Histiocytosis and Rare Infiltrative Diseases
Chapter 97: Eosinophilic Lung Diseases
Chapter 98: Lymphangioleiomyomatosis and Other Cystic Lung Diseases
Chapter 99: Pulmonary Alveolar Proteinosis Syndrome
Chapter 100: Drug-Induced Pulmonary Disease
Section L: Environmental and Occupational Hazards
Chapter 101: Asthma in the Workplace
Chapter 102: Pneumoconioses
Chapter 103: Indoor and Outdoor Air Pollution
Chapter 104: Acute Pulmonary Responses to Toxic Exposures
Chapter 105: Trauma and Blast Injuries
Chapter 106: High Altitude
Chapter 107: Air Travel
Chapter 108: Diving Medicine
Section M: Disorders of the Pleura
Chapter 109: Pleural Effusion
Chapter 110: Pleural Infections
Chapter 111: Pneumothorax
Chapter 112: Chylothorax
Chapter 113: Pleural Fibrosis and Nonexpandable Lung
Chapter 114: Hemothorax
Chapter 115: Pleural Malignancy
Section N: Disorders of the Mediastinum
Chapter 116: Mediastinal Tumors and Cysts
Chapter 117: Mediastinitis and Fibrosing Mediastinitis
Section O: Respiratory Manifestations of Extrapulmonary Disorders
Chapter 118: Pulmonary Complications of HIV Infection
Chapter 119: Pulmonary Complications of Primary Immunodeficiencies
Chapter 120: Pulmonary Complications of Stem Cell and Solid Organ Transplantation
Chapter 121: Pulmonary Complications of Abdominal Diseases
Chapter 122: Pulmonary Complications of Hematologic Diseases
Chapter 123: Pulmonary Complications of Endocrine Diseases
Chapter 124: The Lungs in Obstetric and Gynecologic Diseases
Chapter 125: The Respiratory System and Neuromuscular Diseases
Chapter 126: The Respiratory System and Chest Wall Diseases
Section P: Disorders of Sleep and Control of Breathing
Chapter 127: Consequences of Sleep Disruption
Chapter 128: Sleep-Disordered Breathing: A General Approach
Chapter 129: Obstructive Sleep Apnea
Chapter 130: Central Sleep Apnea
Chapter 131: Obesity Hypoventilation Syndrome
Chapter 132: Sleep-Disordered Breathing: Treatment
Section Q: Management of Respiratory Failure
Chapter 133: Acute Ventilatory Failure
Chapter 134: Acute Respiratory Distress Syndrome
Chapter 135: Mechanical Ventilation
Chapter 136: Noninvasive Ventilation for Acute Respiratory Failure
Chapter 137: Noninvasive and Invasive Ventilation for Chronic Respiratory Failure
Chapter 138: Noninvasive Support of Oxygenation
Chapter 139: Extracorporeal Support of Gas Exchange
Chapter 140: Pulmonary Rehabilitation
Chapter 141: Lung Transplantation
Chapter 142: End-of-Life Care in Respiratory Failure
Chapter 143: Medical Education
Product details
Product details
- Edition: 8
- Latest edition
- Published: October 15, 2026
- Language: English
About the editors
About the editors
VB
V. Courtney Broaddus
Affiliations and expertise
Professor Emeritus, Division of Pulmonary and Critical Care, University of California, San Francisco, USANB
Nirav R. Bhakta
Affiliations and expertise
Associate Professor, Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, USAJE
Joel D. Ernst
Affiliations and expertise
Professor and Chief, Division of Experimental Medicine, University of California, San Francisco, USATK
Talmadge E. King Jr
Affiliations and expertise
Dean, UCSF School of Medicine, Vice Chancellor, Medical Affairs, University of California, San Francisco, USAKS
Kathleen F. Sarmiento
Affiliations and expertise
Professor, Department of Medicine, University of California, San Francisco, San Francisco, CA, USALS
Lynn M. Schnapp
Affiliations and expertise
George R. and Elaine Love Professor Chair of the Department of Medicine University of Wisconsin School of Medicine and Public Health Madison, WI, USARS
Renee D. Stapleton
Affiliations and expertise
Professor of Medicine, Pulmonary and Critical Care Medicine, Larner College of Medicine, University of Vermont, USA