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Multiscale Modeling of Developmental Systems
- 1st Edition, Volume 81 - December 18, 2007
- Editors: Santiago Schnell, Gerald P. Schatten, Philip Maini, Stuart A. Newman, Timothy Newman
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 3 7 4 2 5 3 - 7
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 5 6 5 3 - 6
Mathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at… Read more
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Request a sales quoteMathematical and computational biology is playing an increasingly important role in the biological sciences. This science brings forward unique challenges, many of which are, at the moment, beyond the theoretical techniques available. Developmental biology, due to its complexity, has lagged somewhat behind its sister disciplines (such as molecular biology and population biology) in making use of quantitative modeling to further biological understanding. This volume comprises work that is among the best developmental modeling available and we feel it will do much to remedy this situation.This book is aimed at all those with an interest in the interdisciplinary field of computer and mathematical modeling of multi-cellular and developmental systems. It is also a goal of the Editors to attract more developmental biologists to consider integrating modeling components into their research. Most importantly, this book is intended to serve as a portal into this research area for younger scientists – especially graduate students and post-docs, from both biological and quantitative backgrounds.
* Articles written by leading exponents in the field
* Provides techniques to address multiscale modeling
* Coverage includes a wide spectrum of modeling approaches
* Includes descriptions of the most recent advances in the field
* Provides techniques to address multiscale modeling
* Coverage includes a wide spectrum of modeling approaches
* Includes descriptions of the most recent advances in the field
Graduate students and scientists in developmental biology, mathematical sciences, biomathematics, and general life sciences.
Chapter 1
Introduction
Philip K. Maini, Stuart A. Newman, Timothy J. Newman and Santiago Schnell
Chapter 2
Models of biological pattern formation: from elementary steps to the organization of embryonic axes
Hans Meinhardt
Chapter 3
Robustness of embryonic spatial patterning in Drosophila melanogaster
David Umulis, Michael B. O’Connor and Hans G. Othmer
Chapter 4
Integrating morphogenesis with underlying mechanics and cell biology.
Lance A. Davidson
Chapter 5
The mechanisms underlying primitive streak formation in the chick embryo
Manli Chuai, Cornelis J Weijer
Chapter 6
Grid-free models of multicellular systems, with an application to large-scale vortices accompanying primitive streak formation
T. J. Newman
Chapter 7
Mathematical models for somite formation
Ruth E. Baker, Santiago Schnell and Philip K. Maini
Chapter 8
Coordinated Action of N-CAM, N-cadherin, EphA4 and ephrinB2 Translates Genetic Prepatterns into Structure during Somitogenesis in Chick
James A. Glazier, Ying Zhang, Maciej Swat, Benjamin Zaitlen, Santiago Schnell
Chapter 9
Branched organs: Mechanics of morphogenesis by multiple mechanisms
Sharon R Lubkin
Chapter 10
Multicellular sprouting during vasculogenesis
Andras Czirok, Evan A. Zamir, Andras Szabo and Charles D. Little
Chapter 11
Modelling lung branching morphogenesis
Takashi Miura
Chapter 12
Multiscale Models for Vertebrate Limb Development
Stuart A. Newman, Scott Christley, Tilmann Glimm, H.G.E. Hentschel, Bogdan Kazmierczak, Yong-Tao Zhang, Jianfeng Zhu and Mark Alber
Chapter 13
Tooth morphogenesis in vivo, in vitro and in silico
Isaac Salazar-Ciudad
Chapter 14
Cell mechanics with a 3D kinetic and dynamic weighted Delaunay-triangulation
Michael Meyer-Hermann
Chapter 15
Cellular automata as microscopic models of cell migration in heterogeneous environments
H. Hatzikirou and A. Deutsch
Chapter 16
Multiscale modeling of biological pattern formation
Ramon Grima
Chapter 17
Relating Biophysical Properties Across Scales
Elijah Flenner, Francoise Marga, Adrian Neagu, Ioan Kosztin, Gabor Forgacs
Chapter 18
Complex Multicellular Systems and Immune Competition: New Paradigms Looking for a
Mathematical Theory
N. Bellomo, G. Forni
Introduction
Philip K. Maini, Stuart A. Newman, Timothy J. Newman and Santiago Schnell
Chapter 2
Models of biological pattern formation: from elementary steps to the organization of embryonic axes
Hans Meinhardt
Chapter 3
Robustness of embryonic spatial patterning in Drosophila melanogaster
David Umulis, Michael B. O’Connor and Hans G. Othmer
Chapter 4
Integrating morphogenesis with underlying mechanics and cell biology.
Lance A. Davidson
Chapter 5
The mechanisms underlying primitive streak formation in the chick embryo
Manli Chuai, Cornelis J Weijer
Chapter 6
Grid-free models of multicellular systems, with an application to large-scale vortices accompanying primitive streak formation
T. J. Newman
Chapter 7
Mathematical models for somite formation
Ruth E. Baker, Santiago Schnell and Philip K. Maini
Chapter 8
Coordinated Action of N-CAM, N-cadherin, EphA4 and ephrinB2 Translates Genetic Prepatterns into Structure during Somitogenesis in Chick
James A. Glazier, Ying Zhang, Maciej Swat, Benjamin Zaitlen, Santiago Schnell
Chapter 9
Branched organs: Mechanics of morphogenesis by multiple mechanisms
Sharon R Lubkin
Chapter 10
Multicellular sprouting during vasculogenesis
Andras Czirok, Evan A. Zamir, Andras Szabo and Charles D. Little
Chapter 11
Modelling lung branching morphogenesis
Takashi Miura
Chapter 12
Multiscale Models for Vertebrate Limb Development
Stuart A. Newman, Scott Christley, Tilmann Glimm, H.G.E. Hentschel, Bogdan Kazmierczak, Yong-Tao Zhang, Jianfeng Zhu and Mark Alber
Chapter 13
Tooth morphogenesis in vivo, in vitro and in silico
Isaac Salazar-Ciudad
Chapter 14
Cell mechanics with a 3D kinetic and dynamic weighted Delaunay-triangulation
Michael Meyer-Hermann
Chapter 15
Cellular automata as microscopic models of cell migration in heterogeneous environments
H. Hatzikirou and A. Deutsch
Chapter 16
Multiscale modeling of biological pattern formation
Ramon Grima
Chapter 17
Relating Biophysical Properties Across Scales
Elijah Flenner, Francoise Marga, Adrian Neagu, Ioan Kosztin, Gabor Forgacs
Chapter 18
Complex Multicellular Systems and Immune Competition: New Paradigms Looking for a
Mathematical Theory
N. Bellomo, G. Forni
- No. of pages: 604
- Language: English
- Edition: 1
- Volume: 81
- Published: December 18, 2007
- Imprint: Academic Press
- Hardback ISBN: 9780123742537
- eBook ISBN: 9780080556536
GS
Gerald P. Schatten
Affiliations and expertise
University of Pittsburgh School of Medicine, PA, U.S.A.Read Multiscale Modeling of Developmental Systems on ScienceDirect