Multi-perspective Management of Sleep Disorders, An Issue of Sleep Medicine Clinics

1st Edition, Volume 19-3 - August 7, 2024
Editors: Brendon Yee, Stephen McNamara, Amanda Piper
Language: English
Hardback ISBN:
9 7 8 - 0 - 4 4 3 - 2 9 3 7 4 - 0
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 2 9 3 7 5 - 7

In this issue of Sleep Medicine Clinics, guest editors Drs. Brendon Yee, Stephen McNamara, and Amanda Piper bring their considerable expertise to the topic of Multi-… Read more

Multi-perspective Management of Sleep Disorders, An Issue of Sleep Medicine Clinics

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In this issue of Sleep Medicine Clinics, guest editors Drs. Brendon Yee, Stephen McNamara, and Amanda Piper bring their considerable expertise to the topic of Multi-Perspective Management of Sleep Disorders. Top experts discuss the pathophysiology of chronic respiratory failure (hypercapnic); assessment (including diagnostic tests) of chronic hypercapnic respiratory failure; overlap syndrome; managing heart failure in patients with chronic respiratory failure; the impact of new drugs in improving and maintaining respiratory function; and much more.

Cover image
Title page
Table of Contents
Copyright
Forthcoming Issues
Contributors
Preface
Pathophysiology of Chronic Hypercapnic Respiratory Failure
Key points
Introduction
The physiologic determinants of arterial carbon dioxide
Metabolic carbon dioxide production
Defending against hypercapnia and the vulnerabilities of respiration in sleep
Anatomy and physiology of ventilatory control
Sleep state-related vulnerabilities
The mechanism of oxygen-induced hypercapnia
Central disorders associated with hypoventilation
Neuromuscular diseases and the mechanisms promoting chronic hypercapnia
Restrictive chest wall disorders and the mechanisms promoting chronic hypercapnia
Obesity hypoventilation syndrome and the mechanisms promoting hypercapnia
Chronic obstructive pulmonary disease and the mechanisms producing hypercapnia
Summary
Clinics care points
Assessment of Chronic Hypercapnic Respiratory Failure
Key points
Introduction
The physiology of pulmonary ventilation
The pathophysiology of chronic hypercapnic respiratory failure
Initial clinic assessment of chronic hypercapnic respiratory failure
Clinical assessment of hypercapnic respiratory failure by disorders
Summary
Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea Overlap Syndrome: An Update on the Epidemiology, Pathophysiology, and Management
Key points
Introduction
Prevalence of overlap syndrome
Relationship between obstructive sleep apnea and chronic obstructive pulmonary disease
Pathophysiology
Overlap syndrome and cardiovascular disease
Overlap syndrome and risk of exacerbations
Diagnosis
Treatment
Summary
Initiation of Chronic Non-invasive Ventilation
Key points
Introduction
Initiation of chronic non-invasive ventilation in neuromuscular disease
Initiation of non-invasive ventilation in obesity hypoventilation syndrome
Initiation of non-invasive ventilation in chronic obstructive pulmonary disease
Monitoring during the initiation phase
Summary
Clinics care points
Interfaces for Home Noninvasive Ventilation
Key points
Introduction
Choosing an appropriate mask: clinical considerations
What masks are currently used in the home setting?
Securing the mask–the headgear
Are there physiologic or clinical differences between nasal and oronasal masks?
Technical considerations with different interface types
Potential mask-associated complications
Summary
Clinics care points
Telemonitoring in Non-invasive Ventilation
Key points
Introduction
The technical solutions
Coordination
Clinical application and evidence
Summary
Clinics care points
Disclosures
The Role of High Flow Nasal Therapy in Chronic Respiratory Failure
Key points
Introduction
Physiologic effects of high-flow nasal therapy and why high-flow nasal therapy may be beneficial in chronic hypercapnic respiratory failure
Short term effects of high-flow nasal therapy
Medium term effects of high-flow nasal therapy in chronic hypercapnic respiratory failure
Long term effects of high-flow nasal therapy in chronic hypercapnic respiratory failure
Discussion
Summary
Clinics care points
Impact of Disease-modifying Therapies on Respiratory Function in People with Neuromuscular Disorders
Key points
Introduction
Spinal muscular atrophy
Disease-modifying therapies for spinal muscular atrophy
Summary
Duchenne muscular dystrophy
Disease-modifying therapies for Duchenne muscular dystrophy
Future directions
Summary
Clinics care points
Airway Clearance in Neuromuscular Disease
Key points
Introduction
Cough assessment
Mechanical insufflation-exsufflation Titration
Hyperinflation therapies
Peripheral airway clearance techniques
Challenges
Summary
Palliative Care and Noninvasive Ventilation
Key points
Palliative care—definition and relation to noninvasive ventilation
Advance care planning—definition and relation to noninvasive ventilation
Neuromuscular disease: noninvasive ventilation and palliative care
Chronic obstructive pulmonary disease: noninvasive ventilation and palliative care
High-flow nasal prongs as an alternative to noninvasive ventilation
Breathlessness management
Weaning noninvasive ventilation at the end of life
Voluntary assisted dying and noninvasive ventilation
Self-care for clinicians
Clinics care points

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Multi-perspective Management of Sleep Disorders, An Issue of Sleep Medicine Clinics

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Brendon Yee

Stephen McNamara

Amanda Piper