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Mosaic of Autoimmunity

The Novel Factors of Autoimmune Diseases

  • 1st Edition - February 8, 2019
  • Latest edition
  • Editors: Carlo Perricone, Yehuda Shoenfeld
  • Language: English

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term impl… Read more

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Description

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases.

An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

Key features

  • Highlights the concept of the mosaic of autoimmune manifestations
  • Includes new visions on unsuspected molecules
  • Provides updated knowledge to physicians helping patients with autoimmune diseases
  • Presents thorough, up-to-date information on specific diseases, along with clinical applications

Readership

Researchers and physicians in immunology, autoimmune diseases, genetics, virologists and molecular biologists. Researchers, clinicians, clinical investigators, pathologists, medical students, and graduate students in the biomedical sciences, as well as basic scientists in such fields as immunology, rheumatology, genetics, cell biology and molecular and microbiology

Table of contents

Introduction

1. The history of the mosaic of autoimmunity

2. The novel aspects on the mosaic of autoimmunity　

Cellular and molecular mechanisms

3. B cells

4. B-reg　

5. T cells

6. Th17 cells

7. NK cells

8. Dendritic cells

9. Complement

10. Autoantibodies

11. Anti-DSF70

12. Genetic

13. Epigenetic

14. Post-translational modifications

15. Cytokines and chemokines

16. Autophagy

17. Diagnostic: laboratory　

18. Diagnostic: imaging

The classical factors associated with autoimmunity

19. Hormones

20. Microbiota

21. Infections: Viruses and bacteria

The novel environmental factors associated with autoimmunity

22. Geo-epidemiology

23. Seasonality

24. UV

25. Vitamin D

26. Vitamin D pregnancy and autoimmunity

27. Smell

28. Breast feeding

29. Vaccines

30. Silicone

31. Diet: spicy food and fatty acids

32. Diet: gluten

33. Psychological stress

34. Coffee

35. Obesity

36. Physical activity

37. Smoke

38. Cannabis

39. Bisphenol

40. Prolactin

Peculiar aspects

41. Cancer

42. Paraneoplastic syndromes

Classical autoimmune diseases

43. SLE

44. APS

45. CAPS

46. RA and inflammatory arthritides

47. PsA and Spondyloarthropathies

48. MS, MG and other neurological disorders

49. Systemic slcerosis

50. Sjogren

51. ASIA syndrome

52. Reproductive failure

53. Accelerated atherosclerosis

54. New autoimmune diseases

Treatment of autoimmune diseases

55. Neuroimmunology

56. Vasculitis

57. Personalized Medicine

58. Biologics and Biosimilars

59. Small molecules

60. Helminthes

61. Novel therapies and IVIg

62. Autoimmune and allergic disease

63. EBV Molecular Diagnosis

64. Statin and myositis

65. Autoimmunity and primary immunodeficiency

Product details

  • Edition: 1
  • Latest edition
  • Published: February 8, 2019
  • Language: English

About the editors

CP

Carlo Perricone

Dr. Carlo Perricone, is a ECR in autoimmune diseases, Born in Rome on 19 April 1984. 'Surgeon Specialist in Rheumatology, has a Ph.D. in Immunological Sciences, hematology, and Rheumatics at Sapienza University of Rome. He received with honors the Master Degree in Medicine and Surgery in July 2007 at the University of Rome
Affiliations and expertise
Sapienza University of Rome | La Sapienza, Department of Internal and Specialized Medicine, Rome, Italy

YS

Yehuda Shoenfeld

Professor Yehuda Shoenfeld is the President of the Center for Autoimmune Diseases (present), incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases in Tel Aviv University (since 2002–Present), Emeritus Professor of the Sackler School of Medicine in Tel Aviv University and teaches medical studies and MSc and PhD students (since 1985). Prof. Shoenfeld has edited a series of textbooks entailing "The Mosaic of Autoimmunity," "Autoantibodies," "Infection and Autoimmunity," and "Diagnostic Criteria of Autoimmune Diseases" (Elsevier Pub.). He has served on 36 editorial boards and is the organizer of more than 25 international congresses on autoimmunity. He is the author of > 2000 peer-reviewed papers reported in the field of autoimmunity and internal medicine. More than 65,000 citations.
Affiliations and expertise
Zabludowitcz Center of Autoimmunity, Sheba Medical Center and Reichman University, Herzelya, Israel

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