Molecular Chaperones in Human Disorders
- 1st Edition, Volume 114 - January 9, 2019
- Latest edition
- Editor: Rossen Donev
- Language: English
Molecular Chaperones in Human Disorders, Volume 114 in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in… Read more
Molecular Chaperones in Human Disorders, Volume 114 in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair and their involvement in maintaining chromatin repair, the balance between chromosomal repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Chapters in this new release cover Functional principles and regulation of molecular chaperones, Chaperones and retinal disorders, Protein misfolding and degradation in genetic diseases, Chaperone dysfunction in hereditary myopathic diseases, Diseases caused by functional disorder of molecular chaperones residing in the endoplasmic reticulum, and many other timely topics.
- Describes advances in our understanding on DNA repair mechanisms and the involvement of their dysregulation in promoting diseases
- Provides an ideal resource for a very wide audience of specialists, researchers and students
- Contains timely chapters written by well-renown authorities in their field
- Presents information that is well supported by a number of high quality illustrations, figures and tables
Protein chemists, biochemists, molecular biologists, cell biologists, immunologists, neuroscientists, structural biologists, medical doctors, pharmacologists, computational biochemists and other researchers working in this field. Medical, biology and pharmacology students specializing in this field
1. Functional principles and regulation of molecular chaperones
Johannes Buchner
2. Chaperones and retinal disorders
Nikolai O. Artemyev
3. Protein misfolding and degradation in genetic diseases
Rasmus Hartmann-Petersen
4. Chaperone dysfunction in hereditary myopathic diseases
Andreas Roos
5. Diseases caused by functional disorder of molecular chaperones residing in the endoplasmic reticulum
Masafumi Sakono
6. Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I
Angel Luis Pey
7. Inflammatory response and its relation to sphingolipid metabolism proteins: Targeting inflammation with molecular chaperones
Elif Ozkirimli
8. When safeguarding goes wrong: impact of oxidative stress on proteins homeostasis in health and neurodegenerative disorders
Dana Reichmann
9. Computational approach to unravel the misfolding mechanism of Glucosylceramidase mutations in Gaucher Disease
George Priya Doss P. C
10. Cytosolic quality control proteins, SGTA and the Bag6 complex, in disease
Rivka L. Isaacson
- Edition: 1
- Latest edition
- Volume: 114
- Published: January 9, 2019
- Language: English
RD