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Elsevier

Molecular Biology

Molecular Biology: Academic Cell Update provides an introduction to the fundamental concepts of molecular biology and its applications. It deliberately covers a broad range of… Read more

Description

Molecular Biology: Academic Cell Update provides an introduction to the fundamental concepts of molecular biology and its applications. It deliberately covers a broad range of topics to show that molecular biology is applicable to human medicine and health, as well as veterinary medicine, evolution, agriculture, and other areas. The present Update includes journal specific images and test bank. It also offers vocabulary flashcards.

The book begins by defining some basic concepts in genetics such as biochemical pathways, phenotypes and genotypes, chromosomes, and alleles. It explains the characteristics of cells and organisms, DNA, RNA, and proteins. It also describes genetic processes such as transcription, recombination and repair, regulation, and mutations. The chapters on viruses and bacteria discuss their life cycle, diversity, reproduction, and gene transfer. Later chapters cover topics such as molecular evolution; the isolation, purification, detection, and hybridization of DNA; basic molecular cloning techniques; proteomics; and processes such as the polymerase chain reaction, DNA sequencing, and gene expression screening.

Key features

  • Up to date description of genetic engineering, genomics, and related areas
  • Basic concepts followed by more detailed, specific applications
  • Hundreds of color illustrations enhance key topics and concepts
  • Covers medical, agricultural, and social aspects of molecular biology
  • Organized pedagogy includes running glossaries and keynotes (mini-summaries) to hasten comprehension

Readership

Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture

Table of contents

Chapter 1 Basic GeneticsChapter 2 Cells and OrganismsChapter 3 DNA, RNA and ProteinChapter 4 Genes, Genomes and DNAChapter 5 Cell Division and DNA ReplicationChapter 6 Transcription of GenesChapter 7 Protein Structure and FunctionChapter 8 Protein SynthesisChapter 9 Regulation of Transcription in ProkaryotesChapter 10 Regulation of Transcription in EukaryotesChapter 11 Regulation at the RNA LevelChapter 12 Processing of RNAChapter 13 MutationsChapter 14 Recombination and RepairChapter 15 Mobile DNAChapter 16 PlasmidsChapter 17 VirusesChapter 18 Bacterial GeneticsChapter 19 Diversity of Lower EukaryotesChapter 20 Molecular EvolutionChapter 21 Nucleic Acids: Isolation, Purification, Detection, and HybridizationChapter 22 Recombinant DNA TechnologyChapter 23 The Polymerase Chain ReactionChapter 24 Genomics and DNA SequencingChapter 25 Analysis of Gene ExpressionChapter 26 Proteomics: The Global Analysis of ProteinsGlossaryIndex

Review quotes

"This is an excellent book. It is very lucidly written. Clark covers a suitable set of topics, and treats each topic very thoroughly...He is very up-to-date in his coverage of the material."—John G. Burr, University of Texas at Dallas

"This textbook is very comprehensive, covering nearly all aspects of molecular biology and genetics. The textbook excels in defining key terms in a clear and understable way...The sprinkling of little side stories...keeps the reader interested, and kept me glued throughout the text."—B. Franklin Pugh, Penn State University

"The author did a very good job covering this vast subject and offered many insightful perspectives."—John F. Cannon, University of Missouri

Product details

About the author

DC

David P. Clark

David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave.

Affiliations and expertise
Southern Illinois University