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Mitochondrial Diseases
- 1st Edition, Volume 194 - February 20, 2023
- Editors: Rita Horvath, Michio Hirano, Patrick F. Chinnery
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 1 7 5 1 - 1
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 1 7 6 1 - 0
Mitochondrial Diseases, Volume 194 presents the most common clinical manifestations, providing an up-to-date summaries on the clinical presentations, diagnostic processes, geneti… Read more
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Request a sales quoteThis book is intended for neurologists to help them recognize and manage patients with mitochondrial diseases.
- Examines the pathophysiology of mitochondrial diseases and disorders
- Focuses on neurological symptoms of mitochondrial diseases
- Presents myopathies, neuropathies, epilepsy, ataxia, paraplegias, and more
- Covers histology, metabolism, genetic, and neuroimaging diagnostics
- Summarizes both available and emerging therapies
- Includes clinical trials, the use of biomarkers and reproductive options
Section I. Introduction to Mitochondrial Diseases
1. Mitochondrial disease in neurology – Past, present, and future
Section II. Most Common Neurological Manifestations of Mitochondrial Disease
2. Progressive external ophthalmoplegia
3. Mitochondrial optic neuropathies
4. Leigh syndrome
5. Stroke-like episodes in adult mitochondrial disease
6. Ataxia and spastic paraplegia in mitochondrial disease
7. Peripheral neuropathy in mitochondrial disease
8. Complex neurological and multisystem presentations in mitochondrial disease
Section III. Diagnosing Mitochondrial Disease
9. Investigation of oxidative phosphorylation activity and composition in mitochondrial disease
10. Genetics of mitochondrial diseases: Current approaches for the molecular diagnosis
11. Laboratory and metabolic investigations
12. Neuroimaging in mitochondrial disease
Section IV. Therapy and Future Challenges
13. Currently available therapies in mitochondrial disease
14. Reproductive options in mitochondrial disease
15. Clinical trials in mitochondrial disease
16. Blood biomarkers of mitochondrial disease – One for all or all for one?
17. Experimental therapy for mitochondrial diseases
- No. of pages: 302
- Language: English
- Edition: 1
- Volume: 194
- Published: February 20, 2023
- Imprint: Elsevier
- Hardback ISBN: 9780128217511
- eBook ISBN: 9780128217610
RH
Rita Horvath
MH
Michio Hirano
PC