Mitochondria-targeted Drug Delivery Strategies for Cancer Therapy
- 1st Edition - July 1, 2026
- Latest edition
- Editors: Arun Kumar Singh, Neeraj Mishra, Ashutosh Pareek, Anoop Kumar, Gautam Sethi
- Language: English
Mitochondria-targeted Drug Delivery Strategies for Cancer Therapy explores the innovative use of biocompatible, multifunctional nanoplatforms to target mitochondria for select… Read more
Mitochondria-targeted Drug Delivery Strategies for Cancer Therapy explores the innovative use of biocompatible, multifunctional nanoplatforms to target mitochondria for selective drug delivery, enhancing treatment efficacy while minimizing side effects. This book provides a comprehensive overview of the role of nanotechnology in cancer treatment, reviewing the basics of nanotechnology and cancer biology, advanced nanoengineering strategies, and the development of mitochondria-targeted drug delivery systems, such as liposomal therapies, photosensitizer nanoparticles, and peptides for cancer treatment, along with strategies to modulate mitochondrial functions using nanomaterials. This book is a valuable resource to researchers and scientists interested in the application of nanotechnology for improved cancer therapy as it provides a thorough overview of real-world applications and future research trends, as well as a discussion on overcoming challenges in mitochondrial targeting.
- Reviews the principles of mitochondria-targeted drug delivery, including the design of nanocarriers, mechanisms of mitochondrial targeting, and methods for evaluating delivery efficiency
- Includes case studies and examples from recent research to illustrate the application of nanotechnology in targeting mitochondria for cancer treatment
- Discusses future research directions in this field, including emerging trends and technologies that may further advance mitochondria-targeted drug delivery for cancer treatment
Researchers, scientists, academics, and advanced graduate students in the fields of nanotechnology, cancer biology, drug delivery, and related disciplines. nanotehcnology; nanoparticle; nanocarriers; cancer nanotechnology; cancer nanomedicine; cancer therapy; drug delivery; targeted cancer therapy
1. Introduction of nanotechnology: basic concept and properties
2. Basics of cancer biology, and role of nanotechnology in cancer treatment
3. Nanoparticle-Mediated Drug Delivery in Cancer Therapy: Addressing Drug Resistance Challenges
4. Advancing Targeted Drug Delivery in Malignancy: Nanoengineering Strategies for Enhanced Efficacy
5. Mitochondria in Cancer: Functions, Dysfunction, and Therapeutic Targets
6. Introduction to mitochondria-targeted Drug Delivery in cancer
7. Mitochondria-Targeted Drug Delivery Strategies for Cancer Treatment
8. Mitochondria-Targeted Liposomes in Cancer Therapy
9. Mitochondrial-Targeted Photosensitizers Nanoparticles in Photodynamic Therapy
10. Role of Mitochondria-Penetrating Peptides in Cancer Therapeutics
11. Modulating Mitochondrial Reactive Oxygen Species in Cancer Therapy through Nanomaterials
12. Polymeric Nanoparticles for Mitochondria Targeting Mediated Robust Cancer Therapy
13. Characterization of Mitochondria-Targeted, Nanoparticle-Based Drug-Delivery System
14. Nanoplatforms: Overcoming Challenges in Mitochondrial Targeting for Effective Cancer Treatment
15. Future directions and emerging trends of Mitochondria-Targeted Drug Delivery Strategies: Challenges and future prospects
16. Clinical trials, toxicity studies and real-world applications of mitochondria-targeted drug delivery strategies
2. Basics of cancer biology, and role of nanotechnology in cancer treatment
3. Nanoparticle-Mediated Drug Delivery in Cancer Therapy: Addressing Drug Resistance Challenges
4. Advancing Targeted Drug Delivery in Malignancy: Nanoengineering Strategies for Enhanced Efficacy
5. Mitochondria in Cancer: Functions, Dysfunction, and Therapeutic Targets
6. Introduction to mitochondria-targeted Drug Delivery in cancer
7. Mitochondria-Targeted Drug Delivery Strategies for Cancer Treatment
8. Mitochondria-Targeted Liposomes in Cancer Therapy
9. Mitochondrial-Targeted Photosensitizers Nanoparticles in Photodynamic Therapy
10. Role of Mitochondria-Penetrating Peptides in Cancer Therapeutics
11. Modulating Mitochondrial Reactive Oxygen Species in Cancer Therapy through Nanomaterials
12. Polymeric Nanoparticles for Mitochondria Targeting Mediated Robust Cancer Therapy
13. Characterization of Mitochondria-Targeted, Nanoparticle-Based Drug-Delivery System
14. Nanoplatforms: Overcoming Challenges in Mitochondrial Targeting for Effective Cancer Treatment
15. Future directions and emerging trends of Mitochondria-Targeted Drug Delivery Strategies: Challenges and future prospects
16. Clinical trials, toxicity studies and real-world applications of mitochondria-targeted drug delivery strategies
- Edition: 1
- Latest edition
- Published: July 1, 2026
- Language: English
AS
Arun Kumar Singh
Dr. Arun Kumar Singh is an assistant professor in the Department of Pharmacy at Vivekanand Global University, Jaipur. He completed both his MPharm in Pharmaceutics and his PhD at Galgotias University, Greater Noida. His research strengths lie in AI-driven cancer research, nano-formulation, and the intersection of blockchain, IoT, machine learning, big data, and neuroscience with pharmaceutical science. He has authored books and contributed chapters on big data and cancer, and his work includes reviews published in reputable journals. His research appears across publishers such as IOP, Elsevier, CRC Press, and Wiley, reflecting a broad publication record and ongoing contributions to AI-enabled oncology and advanced drug delivery.
Affiliations and expertise
Assistant Professor, Department of Pharmacy, Vivekanand Global University Jaipur Rajasthan, IndiaNM
Neeraj Mishra
Dr. Neeraj Mishra is a Professor at the Amity Institute of Pharmacy, Gwalior, where he has served since July 2019. He has over 20 years of teaching and research experience and more than 150 international and national publications in novel, localized, targeted, and controlled drug delivery systems, including nano- and microparticles for the treatment of breast and colon cancer and neurodegenerative disorders. Dr. Mishra has authored 25 books and 45 book chapters with leading publishers such as Elsevier, Bentham, Springer, and Wiley, and holds five patents (three international and two Indian). His honors include the Distinguished Professor Awards (2019, 2021), Outstanding Scientist Award (2020), and Best Academician Award (2023). In 2025, he was recognized as one of the World’s Top 2% Scientists by Stanford University and Elsevier.
Affiliations and expertise
Professor and Head of Department, Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University Madhya Pradesh, Gwalior, IndiaAP
Ashutosh Pareek
Dr. Ashutosh Pareek, Associate Professor at Banasthali Vidyapith with over 15 years of experience in pharmaceutical sciences, holds gold medals for his Master's and Bachelor's degrees in Pharmacy. Dr. Pareek specializes in neuropharmacology and innovative drug delivery systems, focusing on neurodegenerative disorders, cancer, and autoimmune diseases. His research includes developing advanced drug delivery systems for immunomodulators like naringenin. Dr. Pareek leads a research team working on these critical health issues and has published over 45 research papers and authored five technical books. He holds an international formulation patent and has received numerous awards, including the Zee National Achievers Award 2023. His work is funded by national and international agencies such as ICMR, DST-SERB, DBT, the American Association of Pharmaceutical Scientists, and the International Brain Research Organization. He serves as a Review Editor for Frontiers in Pharmacology and Frontiers in Oncology and reviews for leading journals by Elsevier, Springer, and Bentham.
Affiliations and expertise
Senior Associate Professor, Department of Pharmacy, Banasthali Vidyapith Banasthali, IndiaAK
Anoop Kumar
Dr. Anoop Kumar is an Assistant Professor in the Department of Pharmacology at Delhi Pharmaceutical Sciences & Research University (DPSRU), India. With a distinguished career, he has previously served as an Assistant Professor and Head at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, and as Head and Associate Professor at ISF College of Pharmacy, Moga, Punjab. Dr. Kumar has also held research positions at Sun Pharmaceutical Industries Limited and Translational Health Science Institute (THSTI). He earned his Ph.D. from Birla Institute of Technology, Mesra, Ranchi, as a DST INSPIRE Fellow. He is an Associate Editor for Health Sciences Review and Acta Neurologica Scandinavica. His research focuses on drug repurposing, clinical trial meta-analysis, pharmacoeconomics, and pharmacovigilance.
Affiliations and expertise
Assistant Professor, Delhi Pharmaceutical Sciences and Research University (DPSRU), IndiaGS
Gautam Sethi
Dr. Gautam Sethi is a tenured Associate Professor in Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore. The focus of his research over the past few years has been to elucidate the mechanism(s) of activation of oncogenic transcription factors by carcinogens and inflammatory agents and the identification of novel inhibitors of these proteins for prevention of and therapy for cancer. The findings of his research work have so far resulted several publications in high impact factor peer reviewed journals and many international awards. He also serves as an editorial board member for over more than 15 international journals.
Affiliations and expertise
Associate Professor, Yong Loo Lin School of Medicine, National University of Singapore, Singapore