Skip to main content
Elsevier

Middleton's Allergy 2-Volume Set

Principles and Practice (Expert Consult Premium Edition - Enhanced Online Features and Print)

  • 8th Edition - October 18, 2013
  • Latest edition
  • Authors: A. Wesley Burks, N. Franklin Adkinson Jr., Bruce S Bochner, William W Busse, Stephen T Holgate, Robert F Lemanske, Robyn E. O'Hehir
  • Language: English

Boasting a worldwide reputation as the leading text in allergy and immunology, Middleton's Allergy continues its steadfast tradition of providing comprehensive coverage of st… Read more

Purchase options

Info / Buy

Description

Boasting a worldwide reputation as the leading text in allergy and immunology, Middleton's Allergy continues its steadfast tradition of providing comprehensive coverage of state-of-the-art basic science, as well as authoritative guidance on the clinical concepts of day-to-day diagnosis and management of allergic disorders. Offering timely information that’s suited for clinicians and researchers alike, Middleton’s is a user-friendly and versatile source for the knowledge you need to provide optimal care to your patients!

"A valuable source of reference and pre-sifted information ...the editors are to be commending in keeping the book up-to-date and clinically valuable." Reviewed by: Imnunology News, March 2015

Key features

  • Stay on top of continuous new developments in clinical allergy and immunology
    •  through online access to the Expert Consult site, which will feature regular updates as well as the fully searchable contents.
  • Find all of the information you need quickly and easily with a glossary of allergy and immunology terms; highlighted key points for each chapter; hundreds of crystal-clear images with a full-color format, and access to relevant websites.

Readership

Allergy, Immunology

Table of contents

Volume 1

SECTION A

Basic Sciences Underlying Allergy and

Immunology

1

Innate Immunity

2

Adaptive Immunity

3

Immunoglobulin Structure and Function

4

Immune Tolerance

5

Cytokines in Allergic Inflammation

6

Cellular Adhesion in Inflammation

7

Chemokines

8

The Complement System

9

Lipid Mediators of Hypersensitivity and Inflammation

10

Molecular Biology and Genetic Engineering

11

Signal Transduction

12

Biology of Lymphocytes

13

Antigen-Presenting Dendritic Cells

14

Biology of Mast Cells and Their Mediators

15

Biology of Basophils

16

Biology of Eosinophils

17

Biology of Neutrophils

18

Biology of Monocytes and Macrophages

19

Airway Epithelial Cells

20

Noncontractile Functions of Airway Smooth Muscle

21

Pathophysiology of Allergic Inflammation

22

Genetics and Epigenetics in Allergic Diseases and Asthma

23

Immunobiology of IgE and IgE Receptors

24

Neuronal Control of Airway Function in Allergy

25

Resolution of Allergic Inflammation

SECTION B

Aerobiology and Allergens

26

The Structure and Function of Allergens

27

Aerobiology of Outdoor Allergens

28

Indoor Allergens

29

Preparation and Standardization of Allergen Extracts

30 Air Pollution: Indoor and Outdoor

31

Particulate and Pollen Interactions

32

Effect of the Food Matrix and Processing on the Allergenic Activity of Foods

SECTION C

The Skin

33

Structure of the Skin and Cutaneous Immunology

34

Atopic Dermatitis

35

Contact Dermatitis

36

Urticaria and Angioedema

37

Hereditary Angioedema and Bradykinin- Mediated Angioedema

38

Immune Complex–Mediated Diseases

SECTION D

The Eye

39

Allergic and Immunologic Diseases of the Eye

SECTION E

Respiratory Tract

40

The Nose and Control of Nasal Airflow

41

Nasal Provocation Testing

42

Allergic and Nonallergic Rhinitis

43

Rhinosinusitis and Nasal Polyps

44

Development, Structure, and Physiology in Normal Lung and in Asthma

45 Respiratory Tract Mucosal Immunology

46

Airway Smooth Muscle Function in Asthma: Extracellular Matrix and Airway Remodeling

47

Airway Mucus and the Mucociliary System

48

Epidemiology of Asthma and Allergic Airway Diseases

49

Ontogeny of Immune Development and Its Relationship to Allergic Diseases and Asthma

50

Asthma Pathogenesis

51

Mouse Models of Allergic Airways Disease

52

Diagnosis of Asthma in Infants and Children

53

Management of Asthma in Infants and Children

54

Diagnosis of Asthma in Adults

55

Management of Asthma in Adolescents and Adults

56

Emergency Treatment and Approach to the Patient with Acute Asthma

57

Approach to the Patient with Exercise- Induced Bronchoconstriction

58

Asthma and Allergic Diseases during Pregnancy

59

Occupational Allergy and Asthma

60

Pathology of Asthma

61

Allergic Bronchopulmonary Aspergillosis and Hypersensitivity Pneumonitis

62

Immunologic Nonasthmatic Diseases of the Lung

63

Approach to the Patient with Chronic Cough

64

Bronchial Challenge Testing

65

Lung Imaging

66

Aerosols and Aerosol Drug Delivery Systems

Volume 2

SECTION F

Gastrointestinal Tract

67

Gastrointestinal Mucosal Immunology

68

Eosinophilic Gastrointestinal Disorders

SECTION G

Systemic Disease

69

Clinical Significance of Immunoglobulin E

70

In Vivo Methods for the Study and Diagnosis of Allergy

71

Approach to the Patient with Recurrent Infections

72

Primary Immunodeficiency Diseases

73

 Human Immunodeficiency Virus and Allergic Disease

74

Laboratory Tests for Allergic and Immunodeficiency Diseases

75

Eosinophilia and Eosinophil-Related Disorders

76

Mastocytosis

77

Anaphylaxis

78

Insect Allergy

79

Drug Allergy

80

Hypersensitivity to Aspirin and Other Nonsteroidal Antiinflammatory Drugs

81

Reactions to Foods

82

Reactions to Food and Drug Additives

83

Oral Food Challenge Testing

84

Food Allergy Management

85

Adverse Reactions to Vaccines for Infectious Diseases

SECTION H

Therapeutics

86

Allergen Control for Prevention and

Management of Allergic Diseases

87

Injection Immunotherapy for Inhalant Allergens

88

Sublingual Immunotherapy for Inhalant Allergens

89

Principles of Pharmacotherapeutics

90

Pharmacogenomics of Asthma Therapies

91

Adherence

92

Anti-Immunoglobulin E Therapy

93

Cytokine-Specific Therapy in Asthma

94

Histamine and H1 Antihistamines

95

Inhaled β2-Agonists

96

Theophylline and Phosphodiesterase Inhibitors

97 Anticholinergic Therapies

98

The Chromones: Cromolyn Sodium and Nedocromil Sodium

99

Glucocorticosteroids

100

Antileukotriene Therapy in Asthma

101

Unconventional Theories and Unproven Methods in Allergy

102

Complementary and Alternative Medicine

Appendixes

APPENDIX A

CD Molecules

APPENDIX B

Internet Resources for Allergy and

Immunology Professionals

Review quotes

"The chapter on anaphylaxis is an excellent summary, particularly Box 77-7 covering the differential diagnosis. As usual, the chapter on unconventional theories is a masterpiece of debunking nonsense allergy, with a robust approach to looking for supportive scientific studies. This is a must-read chapter for all practicing allergists. Equally the following chapter on complementary and alternative medicine gives a useful summary of philosophies of the main complementary therapies." Reviewed by Imnunology News, Mar 2015

Product details

  • Edition: 8
  • Latest edition
  • Published: October 18, 2013
  • Language: English

About the authors

AB

A. Wesley Burks

Affiliations and expertise
Dean, UNC School of Medicine; CEO of UNC Health, The University of North Carolina at Chapel Hill, USA

NA

N. Franklin Adkinson Jr.

Affiliations and expertise
Professor of Medicine, Division of Allergy and Clinical Immunology, Department of Medicine, John Hopkins University School of Medicine, Baltimore, Maryland, USA

BB

Bruce S Bochner

Affiliations and expertise
Professor of Medicine and Director, Division of Allergy and Clinical Immunology, Department of Medicine, John Hopkins University of Medicine, Baltimore, Maryland, USA

WB

William W Busse

Affiliations and expertise
Professor of Medicine, Department of Medicine, Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

SH

Stephen T Holgate

Affiliations and expertise
Clinical Professor of Immunopharmacology Medical Faculty in Clinical and Experimental Sciences

RL

Robert F Lemanske

Affiliations and expertise
Professor of Pediatrics & Medicine, Head, Division of Pediatric Allergy, Immunology & Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin USA

RO

Robyn E. O'Hehir

Affiliations and expertise
Alfred Hospital and Monash University, Department of Allergy, Immunology, and Respiratory Medicine, Australia

View book on ScienceDirect

Read Middleton's Allergy 2-Volume Set on ScienceDirect