Meningioma, An Issue of Neurosurgery Clinics of North America

1st Edition, Volume 34-3 - May 24, 2023
Editors: Randy L. Jensen, Gabriel Zada
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 3 8 4 9 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 3 8 5 0 - 1

In this issue of Neurosurgery Clinics, guest editors Drs. Randy L. Jensen and Gabriel Zada bring their considerable expertise to the topic of Meningioma. Top experts in the field… Read more

Meningioma, An Issue of Neurosurgery Clinics of North America

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In this issue of Neurosurgery Clinics, guest editors Drs. Randy L. Jensen and Gabriel Zada bring their considerable expertise to the topic of Meningioma. Top experts in the field cover key topics such as genomic and epigenomic landscape of meningioma; current pathology of meningiomas; medical management of meningiomas; endoscope endonasal and keyhole surgery for skull base meningiomas; open craniotomy for meningiomas; and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Histopathologic and Molecular Evaluation of Meningioma
Key points
Common histologic features and frozen section
World Health Organization CNS tumor grading criteria
CNS World Health Organization Grade 2 meningioma
CNS World Health Organization Grade 3 meningioma
Diagnostic and prognostic immunohistochemistry
Histopathologic differential diagnoses
DNA methylation profiling in meningioma
Summary
Clinics care points
Disclosure
Medical Management of Meningiomas
Key points
Introduction
Genomic studies in meningioma
Meningioma mutations
Meningioma immunomodulation
Emerging approaches/clinical trials
Summary
Disclosure
Declaration of Interests
Advanced Meningioma Imaging
Key points
Introduction
Imaging features of meningiomas
Appearance on computed tomography
Appearance on magnetic resonance imaging
Positron emission tomography
Differential diagnosis
Grading of meningioma
Treatment planning
Response prediction and response assessment
Future directions
Summary
Clinics care points
Disclosure
Incidental Meningiomas: Potential Predictors of Growth and Current State of Management
Key points
Introduction
Epidemiology
Radiographic studies
Management
Clinical implications
Summary
Clinics care points
Declarations
Conflicts of interest
Endovascular Embolization of Intracranial Meningiomas
Key points
Introduction
Discussion
Summary
Clinics care points
Disclosures
Open Surgical Approaches for Meningiomas
Key points
Introduction
Frontotemporal craniotomy and its variants
Bicoronal craniotomy
Transpetrosal approach
Retrosigmoid craniotomy
Transcondylar craniotomy
Craniotomies in falcotentorial meningiomas
Summary
Clinics care points
Disclosures
Financial support
Endoscopic Endonasal and Keyhole Surgery for Skull Base Meningiomas
Key points
Introduction
Supraorbital keyhole approach
Surgical technique
Endoscopic endonasal approach
Surgical technique
Discussion
Conflicts of interest
Prior presentations
Clinics care points
Management of Intraventricular Meningiomas
Key points
Introduction
Epidemiology
Patient evaluation and preoperative considerations
Surgical management of intraventricular meningiomas
Intraventricular locations
Meningiomas of the lateral ventricles
Port-based approaches for intraventricular meningioma? Indications?
Meningiomas of the third ventricle
Meningiomas of the fourth ventricle
Functional and neurologic outcomes
Tumor recurrence
Summary
Clinics care points
Disclosure
Spheno-Orbital Meningiomas
Key points
Introduction
Summary
Clinics care points
Authors’ contributions
Funding
Conflicts of interest/competing interests
Data availability
Code availability
Ethical approval
Consent to participate
Consent for publication
Spinal Meningiomas: Diagnosis, Surgical Management, and Adjuvant Therapies
Key points
Introduction
Patient evaluation
Surgical approach
Functional and neurological outcome
Spinal meningioma recurrence
Pharmacologic treatment options
Adjuvant radiotherapy and radiosurgery
Summary
Clinics care points
Disclosure
Management of Atypical and Anaplastic Meningiomas
Key points
Introduction
Patient evaluation overview
Surgical treatment options
Brachytherapy
Radiotherapy treatment options
Pharmacologic treatment options
Treatment resistance/complications
Experimental therapies
Evaluation of outcome and long-term recommendations
Summary
Clinics care points
Funding
Novel Systemic Approaches for the Management of Meningiomas: Immunotherapy and Targeted Therapies
Key points
Introduction
New molecularly driven grading of the World Health Organization classification of meningiomas
Exploring the tumor microenvironment and potential vulnerabilities
Summary
Disclosures
Stereotactic Radiosurgery for Intracranial Meningiomas
Key points
Introduction
Stereotactic radiosurgery for WHO Grade I meningiomas
Summary
Conflict of interest
The Role of Radiotherapy in the Treatment of Higher-Grade Meningioma
Key points
Background
Discussion
Summary
Clinics care points
Disclosure
Modeling Meningiomas: Optimizing Treatment Approach
Key points
Introduction
Methods
Results
Discussion
Summary
Clinics care points
Disclosures
Funding
High-Value Care Outcomes of Meningiomas
Key points
Introduction
Major research findings
Summary
Clinics care points
Financial disclosure
Conflict of interest

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Meningioma, An Issue of Neurosurgery Clinics of North America

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Randy L. Jensen

Gabriel Zada