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Melanoma, An Issue of Clinics in Plastic Surgery
- 1st Edition, Volume 48-4 - September 9, 2021
- Editors: Brian R. Gastman, Michael W. Neumeister
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 8 1 3 2 1 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 1 3 2 2 - 8
This issue of Clinics in Plastic Surgery, Guest Edited by Drs. Brian R. Gastman and Michael W. Neumeister, is dedicated to Melanoma. This issue is one of four selected each year.… Read more
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Request a sales quoteThis issue of Clinics in Plastic Surgery, Guest Edited by Drs. Brian R. Gastman and Michael W. Neumeister, is dedicated to Melanoma. This issue is one of four selected each year. Articles in this issue include, but are not limited to: Melanoma risk factors and prevention, Biology and signaling pathways of melanoma, Immunobiology of melanoma, Clinical diagnosis and classification, Histopathologic and molecular diagnosis of melanoma, AJCC staging and other platforms to assess prognosis and risk, Current treatment guidelines of primary melanoma including wide excision and use of sentinel node biopsy, Dermatologic follow-up and assessment of suspicious lesions, Immunotherapy of melanoma, Targeted therapies for melanoma, Non-operative intra-tumoral therapies, Role of radiation for locoregional and distant metastatic melanoma, Adjuvant and neoadjuvant therapy for melanoma, Surgery of the nodal basins for trunk and extremity melanoma, Extirpative considerations of melanoma of the head and neck, Treatment of lentigo melanoma of the head and neck, Reconstructive considerations of melanoma of the head and neck, Melanoma of the hands and feet, Rare variants of melanoma, and Emerging therapies for melanoma.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Preface
- Melanoma Risk Factors and Prevention
- Key points
- Introduction
- Summary
- Clinics care points
- Canonical Signaling Pathways in Melanoma
- Key points
- Introduction
- Summary
- Immunobiology of Melanoma
- Key points
- Introduction
- Cancer immunoediting and immunosurveillance
- Summary
- Clinics care points
- Clinical Diagnosis and Classification: Including Biopsy Techniques and Noninvasive Imaging
- Key points
- Introduction
- History
- Physical examination
- ABCDE’s of melanoma
- Classification
- In-transit metastases
- Lymph node examination
- Dermoscopy examination
- Reflectance confocal microscopy
- Computer-based technology
- Biopsy
- Laboratory testing
- Imaging
- Discussion
- Clinics care points
- Histopathologic and Molecular Diagnosis of Melanoma
- Key points
- Introduction
- Histopathology of melanoma
- The melanoma report
- Problem areas
- Immunohistochemistry
- Molecular testing
- Sentinel lymph node pathology
- Summary
- Clinics care points
- American Joint Committee on Cancer Staging and Other Platforms to Assess Prognosis and Risk
- Key points
- Introduction
- Eighth edition American Joint Committee on Cancer staging system
- T category
- N category
- M category
- Prognostic stage groups
- Approach to staging patients with multiple primary melanomas
- Approach to staging patients after neoadjuvant therapy
- Approach to staging patients after recurrence/retreatment
- Summary
- Clinics care points
- Sentinel Lymph Node Biopsy, Lymph Node Dissection, and Lymphedema Management Options in Melanoma
- Key points
- Introduction
- Sentinel lymph node biopsy
- Completion lymph node dissection
- Lymphedema
- Summary
- Clinics care points
- Dermatologic Follow-up and Assessment of Suspicious Lesions
- Key points
- Introduction
- Background
- Current guidelines for melanoma surveillance
- Discussion
- Summary
- Clinics care points
- Non-Operative Options for Loco-regional Melanoma
- Key points
- Introduction
- Summary
- Clinics care points
- Radiation Therapy for Local Cutaneous Melanoma
- Key points
- Introduction
- Summary
- Clinics care points
- Adjuvant and Neoadjuvant Therapeutics for the Treatment of Cutaneous Melanoma
- Key points
- Introduction
- Immune therapy
- Targeted therapy
- Oncolytic vaccines
- Summary
- Clinics care points
- Disclosure
- Extirpative Considerations of Melanoma of the Head and Neck
- Key points
- Introduction
- Demographics
- Risk factors
- Types of melanoma in the head and neck
- Prognostic factors and survival
- Biopsy
- Workup
- Current staging
- Surgical treatment
- Indications for sentinel lymph node investigation
- Unique problems of head and neck sentinel node techniques
- Treatment of lymph nodes based on sentinel lymph node biopsy
- Summary
- Clinics care points
- Lentigo Maligna
- Key points
- Introduction
- Cause
- Epidemiology
- Presentation and diagnosis
- Prognosis and staging
- Treatments
- Summary
- Clinics care points
- Disclosure
- Spitz Nevus: Review and Update
- Key points
- Introduction
- Epidemiology
- History
- Clinical presentation
- Differential diagnosis
- Diagnosis
- Dermoscopic features
- Pathology
- Atypical Spitz nevus pathology
- Pathologic subtypes of Spitz nevus
- Ancillary tests
- Molecular studies
- Treatment of Spitz nevus
- Sentinel lymph node biopsy
- Evolution of Spitz nevus
- Prognosis
- Summary
- Clinics care points
- Melanoma of the Hands and Feet (With Reconstruction)
- Key points
- Importance of hand and foot melanoma
- Major histologic subtypes of melanoma
- Topical distribution
- Acral lentiginous melanoma
- Subungual melanoma
- Amelanotic melanoma
- Prognosis of melanoma of the hands and feet
- Treatment (surgical management)
- Clinics care points
- Melanoma in Pregnancy and Pediatrics
- Key points
- Pregnancy-associated melanoma
- Pediatrics melanoma
- Clinics care points
- Mucosal Melanoma
- Key points
- Introduction
- Summary
- Clinics care points
- Emerging Therapies in the Treatment of Advanced Melanoma
- Key points
- Introduction
- Immunotherapy
- Targeted therapy
- Combined immunotherapy and targeted therapy
- Intratumoral therapy
- Cytokine therapy
- Adoptive Cell Therapy
- Vaccine therapy
- Summary
- Clinics care points
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 48-4
- Published: September 9, 2021
- Imprint: Elsevier
- Hardback ISBN: 9780323813211
- eBook ISBN: 9780323813228
BG
Brian R. Gastman
Affiliations and expertise
Associate Professor/Staff
Department of Plastic Surgery
Cleveland Clinic
Cleveland, OH, USAMN
Michael W. Neumeister
Affiliations and expertise
Southern Illinois University School of Medicine