LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Holiday book sale: Save up to 30% on print and eBooks. No promo code needed.
Save up to 30% on print and eBooks.
1st Edition, Volume 52 - September 6, 2019
Editor: Kelly Chibale
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this… Read more
LIMITED OFFER
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic whole cell screening- approaches. Regarding the latter, mechanism of action studies through target identification are also illustrated.
Medicinal chemists, synthetic chemists, biologists, pharmacologists and clinicians
1. Tuberculosis
Steven J. Berthel, Christopher B. Cooper and Nader P. Fotouhi
2. Antituberculosis agents: Beyond medicinal chemistry rules
Marco Pieroni
3. Development of MmpL3 inhibitors for tuberculosis treatment
Giovanna Poce, Sara Consalvi, Giulia Venditti, Cristina Scarpecci and Mariangela Biava
4. Inhibitors of enzymes in the electron transport chain of Mycobacterium tuberculosis
Andrew M. Thompson and William A. Denny
5. Recent advances in the design of inhibitors of mycobacterial transcriptional regulators to boost thioamides anti-tubercular activity and circumvent acquired-resistance
Nicolas Willand, Marion Flipo, Baptiste Villemagne, Alain Baulard and Benoit Deprez
6. Sustainable anti-trypanosomatid drugs: An aspirational goal for medicinal chemistry
Maria Laura Bolognesi
KC