Mechanotransduction
Cell Signaling to Cell Response
- 1st Edition - November 18, 2020
- Imprint: Academic Press
- Author: Paul A. Sundaram
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 7 8 8 2 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 7 8 8 3 - 6
Mechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an extern… Read more
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Request a sales quoteMechanotransduction: Cell Signaling to Cell Response covers the cell machinery responsible for the process of mechanotransduction and the manner in which cells respond to an external mechanical stimulus. The effect of mechanical stimulus on individual cells and entire tissues is discussed, with an emphasis on the practical results of this physiological process. Mechanotransduction of stem cells and cancerous cells are also covered, along with future directions in this yet nascent field. This book gives insights on basic processes that occur (or may occur) in the human body as a result of the application of mechanical stimulus.
It is ideal for both biomedical engineers and biologists, and is an ideal resource for teaching. It provides a current state of conceptual and practical aspects of the field and will enable students and professionals to venture further into this incipient area which is of fundamental importance to biomedical engineering and biology fields.
- Covers fundamental concepts of signaling in cells as a result of mechanical stimulus
- Includes the physiological results of mechanical stimulus on the human body
- Explores the advantages of mechanical loads on the human body
Advanced undergraduate and graduate students in the biomedical engineering and biology fields; professionals in biomedical engineering and medical fields who carry out research in the area of mechanical stimulus on cells and tissues
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Preface
- Acknowledgments
- Foreword
- Chapter 1. Introduction
- Abstract
- Chapter 2. Cell signaling: An overview
- Abstract
- 2.1 Introduction
- 2.2 Modes of cell communication
- 2.3 Phases in cell signaling
- 2.4 Response
- 2.5 Mechanical signaling in cells
- Chapter 3. Cell signaling under mechanical stimulus in specific cell types
- Abstract
- 3.1 Introduction
- 3.2 Forces acting on cells
- 3.3 Modes of mechanosensing
- 3.4 Factors affecting general cell response
- 3.5 Cell mechanotransduction in musculoskeletal tissue
- 3.6 Cell mechanotransduction in cartilage
- 3.7 Cellular mechanotransduction in pulmonary tissue
- 3.8 Cell mechanotransduction is the cardiovascular system
- 3.9 Cell mechanotransduction in nerve tissue
- Chapter 4. Cell characteristics resulting from mechanical stimulus
- Abstract
- 4.1 Introduction
- 4.2 Effect of mechanical stimuli on normal cells
- 4.3 Effect of mechanical stimuli on stem cells
- 4.4 Effect of mechanical stimuli on cancer cells
- 4.5 The role of cell adhesion molecules in mechanosensing
- 4.6 Cellular proliferation
- 4.7 Extracellular matrix remodeling
- Chapter 5. Tissue mechanotransduction
- Abstract
- 5.1 Introduction
- 5.2 Signal characteristics
- 5.3 Signal control: Structural and secretory factors
- 5.4 Musculoskeletal system
- 5.5 Pulmonary system
- 5.6 Cardiovascular system
- 5.7 Nervous system
- Chapter 6. Mechanotherapy
- Abstract
- 6.1 Introduction
- 6.2 Mechanotransduction and disease
- 6.3 Mechanotherapy: Molecular scale
- 6.4 Mechanotherapy: Tissue level
- 6.5 Emerging trends in mechanotherapy
- 6.6 Cancer therapy and mechanotransduction
- 6.7 Other therapeutic effects of mechanical stimulus
- Chapter 7. Future thrusts in the field of mechanotransduction
- Abstract
- Bibliography
- Index
- Edition: 1
- Published: November 18, 2020
- No. of pages (Paperback): 158
- No. of pages (eBook): 158
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780128178829
- eBook ISBN: 9780128178836
PS
Paul A. Sundaram
Paul Sundaram has been working in materials science for the last thirty years. Over the last twelve years, he has focused his research and teaching in the area of biomaterials and the effects of mechanical stimuli on cells. He has approximately 100 publications in journals and conferences.
Affiliations and expertise
Professor of Mechanical Engineering, University of Puerto RicoRead Mechanotransduction on ScienceDirect