
Mechanics in Development and Disease
- 1st Edition, Volume 160 - June 27, 2024
- Imprint: Academic Press
- Editors: Celeste M. Nelson, Lance Davidson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 0 3 2 - 8
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 0 3 3 - 5
Mechanics in Development and Disease, Volume 160 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting in… Read more

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Request a sales quoteMechanics in Development and Disease, Volume 160 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Gut developmental mechanics, Long bone developmental mechanics, Cranial plate fusion developmental mechanics, Mechanobiology and vasculogenesis, Morphogenesis and mechanics of the developing inner ear, Morphogenesis and mechanics of body wall closure in mammals, Salivary bud developmental mechanics, Lateral plate mesoderm developmental mechanics, Biomechanics of human embryo implantation, gastrulation, and organ formation, Mechanics of lung development across species, Mechanics early development in vertebrates.
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- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Chapter One: Salivary gland developmental mechanics
- Abstract
- 1 Introduction
- 2 Epithelial cell mechanics in salivary gland morphogenesis
- 3 Basement membrane mechanics in salivary gland morphogenesis
- 4 Mechanical contributions by the mesenchyme
- 5 Concluding remarks
- References
- Chapter Two: The fusion of physics and biology in early mammalian embryogenesis
- Abstract
- 1 Introduction to early mammalian embryogenesis: from blastulation to gastrulation
- 2 Blastulation
- 3 Implantation
- 4 Gastrulation
- 5 Outlook on the future of biomechanics in embryogenesis: a role for embryo models
- Acknowledgment
- References
- Chapter Three: Biophysics of morphogenesis in the vertebrate lung
- Abstract
- Abbreviations
- 1 Introduction to the functional anatomy of the vertebrate lung
- 2 Biophysics of branch initiation in the mammalian lung
- 3 Active folding during branch initiation in the avian lung
- 4 Pressure-driven expansion of the epithelium in the lizard lung
- 5 Conceptual framework—mesenchyme is the architect
- 6 Conclusions and outlook
- Acknowledgments
- References
- Chapter Four: Gears of life: A primer on the simple machines that shape the embryo
- Abstract
- 1 Self-assembly and morphogenesis
- 2 Mechanical principles of morphogenesis
- 3 Simple machines
- 4 Understanding morphogenesis through models
- 5 Lessons from embryonic and cell culture models
- 6 Supracellular movements
- 7 Conclusion
- Acknowledgments
- References
- Edition: 1
- Volume: 160
- Published: June 27, 2024
- Imprint: Academic Press
- No. of pages: 362
- Language: English
- Hardback ISBN: 9780128240328
- eBook ISBN: 9780128240335
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Celeste M. Nelson
Celeste M. Nelson is at Princeton University, Department of Chemical & Biological Engineering, Princeton, NJ, USA
Affiliations and expertise
Princeton University, Princeton, NJ, USALD
Lance Davidson
Lance Davidson, William Kepler Whiteford Professor, BioEngineering, Dev Biology, Comp. and Systems Biology, University of Pittsburgh,
Pittsburgh, PA, USA
Affiliations and expertise
University of Pittsburgh, Pittsburgh, PA, USARead Mechanics in Development and Disease on ScienceDirect